Tabussam Tufail

Dr. Tabussam Tufail

Diet and Nutritional Sciences, The University of Lahore, Lahore, Punjab, Pakistan
orcid

Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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16 October 2024 in Food Science & Nutrition
Verified
Journal Article
Open access
TTTabussam Tufail
Tabussam Tufail
HAHuma Bader Ul Ain
Huma Bader Ul Ain
SNSana Noreen
Sana Noreen
AIali ikram
ali ikram
Muhammad Tayyab ArshadMuhammad Tayyab Arshad
Muhammad Tayyab Arshad
MAMuhammed Adem Abdullahi
Muhammed Adem Abdullahi
Certain carotene components, such as lycopene and beta‐carotene, are found in tomatoes, carrots, sweet potatoes, etc. and are good for human health. It gives plants their distinctive red color. A class of lipid‐soluble natural pigments known as carotenoids is the precursor of vitamin A and is vital for antioxidant defense against peroxides in cells and tissues. This review provides an overview of the current state of knowledge and research on the sources, structures, physiochemical properties, absorption and metabolism, functional advantages, and prevention of many diseases associated with lycopene and beta‐carotene. These antioxidants have been linked to a lower risk of cardiovascular disease and cancer, and they also help draw pollinators to flowers. Carrots and sweet potatoes are also rich sources of beta‐carotene, which strengthens the immune system and improves eye health. The vivid color of many plants reproductive organs, including flowers and fruits, is caused by carotenoid, a secondary metabolite that is produced in plastids. The distinctive red color and many other health advantages are attributed to lycopene. When ingested through food or supplements, lycopene and beta‐carotene help manage and prevent a number of diseases, including cancer, metabolic, inflammatory, cardiovascular, hepatic, ophthalmic, skeletal, and infertility disorders. The main point is that toxicity is uncommon, and these carotenoids are generally accepted to be safe at different doses. Including these nutrients in your diet can improve your general health and provide illness prevention.

23 June 2021 in Food Science & Nutrition
Verified
Journal Article
Open access
PDF file
AIAli Ikram
Ali Ikram
FSFarhan Saeed
Farhan Saeed
MAMuhammad Afzaal
Muhammad Afzaal
AIAli Imran
Ali Imran
BNBushra Niaz
Bushra Niaz
FAFaqir Muhammad Anjum
Faqir Muhammad Anjum
Scientific literature is evident that the germinated seeds possess a promising potential for essential nutrients, flavors, and textural attributes over nongerminated grain. In recent decades, sprouting has also been investigated as a potential green food engineering technique to boost the nutritive profile of grains. Sprouting grains have multifold applications in different fields such as baking, pharmaceutical, and cosmetic industries. During sprouting, shifting of molecular structures to macroscopic takes place. Sprouting reactivates the grain metabolism which leads to the catabolism and degradation of antinutrient and macronutrient compounds. These modifications have an effect on human health and on the nutritional content of the foodstuffs. Sprouting grains have high bioactivity against diabetes and cancer. Germination is also an outstanding green food development technique to increase the seed nutritive profile in terms of quality. The present review focuses on the sprouting of grains, changes in nutritional profile, and the technological exploration of sprouted grains.

16 February 2024 in Nutrients
Verified
Journal Article
Open access
PDF file
MVMuhammad Safiullah Virk
Muhammad Safiullah Virk
MVMuhammad Abdulrehman Virk
Muhammad Abdulrehman Virk
YHYufeng He
Yufeng He
TTTabussam Tufail
Tabussam Tufail
MGMehak Gul
Mehak Gul
XRXiaofeng Ren
Xiaofeng Ren
Several billion microorganisms reside in the gastrointestinal lumen, including viruses, bacteria, fungi, and yeast. Among them, probiotics were primarily used to cure digestive disorders such as intestinal infections and diarrhea; however, with a paradigm shift towards alleviating health through food, their importance is large. Moreover, recent studies have changed the perspective that probiotics prevent numerous ailments in the major organs. Probiotics primarily produce biologically active compounds targeting discommodious pathogens. This review demonstrates the implications of using probiotics from different genres to prevent and alleviate ailments in the primary human organs. The findings reveal that probiotics immediately activate anti-inflammatory mechanisms by producing anti-inflammatory cytokines such as interleukin (IL)-4, IL-10, IL-11, and IL-13, and hindering pro-inflammatory cytokines such as IL-1, IL-6, and TNF-α by involving regulatory T cells (Tregs) and T helper cells (Th cells). Several strains of Lactobacillus plantarum, Lactobacillus rhamnosus, Lactobacillus casei, Lactobacillus reuteri, Bifidobacterium longum, and Bifidobacterium breve have been listed among the probiotics that are excellent in alleviating various simple to complex ailments. Therefore, the importance of probiotics necessitates robust research to unveil the implications of probiotics, including the potency of strains, the optimal dosages, the combination of probiotics, their habitat in the host, the host response, and other pertinent factors.

25 November 2020 in Food Science & Nutrition
Verified
Journal Article
Open access
PDF file
MIMuhammad Imran
Muhammad Imran
FSFarhan Saeed
Farhan Saeed
SGSyed Amir Gilani
Syed Amir Gilani
MSMohammad Ali Shariati
Mohammad Ali Shariati
AIAli Imran
Ali Imran
FAFaqir M. Anjum
Faqir M. Anjum
Despite the provision of safe and cost‐effective chemopreventive cancer approaches, still there are requirements to enhance their efficiency. The use of dietary agents as phytochemicals plays an imperative role against different human cancer cell lines. Among these novel dietary agents, fisetin (3,3′,4′,7‐tetrahydroxyflavone) is present in different fruits and vegetables such as apple, persimmon, grape, strawberry, cucumber, and onion. Being a potent anticancer agent, fisetin has been used to inhibit stages in the cancer cells (proliferation, invasion), prevent cell cycle progression, inhibit cell growth, induce apoptosis, cause polymerase (PARP) cleavage, and modulate the expressions of Bcl‐2 family proteins in different cancer cell lines (HT‐29, U266, MDA‐MB‐231, BT549, and PC‐3M‐luc‐6), respectively. Further, fisetin also suppresses the activation of the PKCα/ROS/ERK1/2 and p38 MAPK signaling pathways, reduces the NF‐κB activation, and down‐regulates the level of the oncoprotein securin. Fisetin also inhibited cell division and proliferation and invasion as well as lowered the TET1 expression levels. The current review article highlights and discusses the anticancer role of fisetin in cell cultures and animal and human studies. Conclusively, fisetin as a polyphenol with pleiotropic pharmacological properties showed promising anticancer activity in a wide range of cancers. Fisetin suppresses the cancer cell stages, prevents progression in cell cycle and cell growth, and induces apoptosis.

20 July 2023 in International Journal of Food Properties
Verified
Journal Article
Open access
ZMZarina Mushtaq
Zarina Mushtaq
NSNabeelah Bibi Sadeer
Nabeelah Bibi Sadeer
Muzzamal HussainMuzzamal Hussain
Muzzamal Hussain
MAMahwish
Mahwish
SASuliman Alsagaby
Suliman Alsagaby
MMMohamad Fawzi Mahomoodally
Mohamad Fawzi Mahomoodally

27 February 2021 in Food Science & Nutrition
Verified
Journal Article
Open access
PDF file
TTTabussam Tufail
Tabussam Tufail
FSFarhan Saeed
Farhan Saeed
MAMuhammad Afzaal
Muhammad Afzaal
HAHuma Bader Ul Ain
Huma Bader Ul Ain
SGSyed Amir Gilani
Syed Amir Gilani
FAFaqir M. Anjum
Faqir M. Anjum
In millennia, much attention has been paid toward agro‐industrial waste which consists of lignin and cellulosic biomass. In this perspective, biomass waste which consists of lignocellulosic mass is an inexpensive, renewable, abundant that provides a unique natural resource for large‐scale and cost‐effective bioenergy collection. In this current scenario, efforts are directed to briefly review the agro‐industrial lignocellulosic biomass as a broad spectrum of numerous functional ingredients, its utilization, and respective health benefits with special to wheat straw. Wheat straw is lignocellulosic mass owing to the presence of cellulose, hemicellulose, and lignin. Its microbial culture is the most important and well adjusted, for a variety of applications in the fermentation substrate, feed, food, medicine, industry, and agriculture in order to increase soil fertility. In industrial fermentation, wheat straw can be used as substrates for the production of a wide range of hydrolytic enzymes, drugs, metabolites, and other biofuels as a low‐cost substrate or a natural source. Conclusively, wheat straw is the best source to produce bioethanol, biogas, and biohydrogen in biorefineries because it is a renewable, widely distributed, and easily available with very low cost, and its consumption is protected and environment friendly. Wheat straw is a moiety which has health benefits including anti‐inflammatory, antimicrobial, anti‐artherogenic, anti‐allergenic, antioxidant, antithrombotic, etc.