Existing research suggests that regions can develop their long-term competitive advantage through well-functioning interregional innovation cooperation. In this article, we use the example of innovation in small and medium-sized agri-food enterprises (SMEs) to scrutinise and compare regional innovation approaches on each side of the Dutch-German border and explore how they can converge into a cross-border innovation space. Particular attention is paid to the role of academic institutions and innovation brokers in creating a common innovation space. We explore how differences between two cross-border regions can be harnessed to enhance the impact of innovation, and how this may lead to what we describe as hybridisation effects. In the empirical analysis, we apply the concept of hybridisation to a cross-border innovation space, something that, as far as we are aware, has not been done before. We empirically ground the concepts of a cross-border innovation space and hybridisation and illustrate how relative regional strengths can lead to hybridisation effects. We conclude that differences in economic structures, institutional set-ups, visions and identities inherent in cross-border spaces are not only hindrances, but also opportunities, and we highlight the importance of these complementary strengths and the potential for their strategic use by regional innovation actors. Our findings are highly relevant for the further development of the Interreg Europe programme and the implementation of the EU’s Territorial Agenda 2030.

The European Union fosters cooperation in cross-border regions through the European Cohesion Policy (ECP). The implementation of ECP instruments requires a participatory approach, in which stakeholders’ views are acknowledged. However, the multiple of views among and between stakeholders of cross-border initiatives complicate their involvement in a participatory approach. A prerequisite for a meaningful involvement of all stakeholders is an in-depth understanding of their viewpoints on what facilitates cross-border cooperation. However, to date, these viewpoints are poorly understood. This study aims to identify and analyse stakeholders’ viewpoints on the facilitation of cross-border cooperation. The viewpoints of a sample of entrepreneurs, members of education institutes, and members from local institutions (policymakers and industry representatives) in the Dutch-German cross-border region Rhine-Waal were collected via Q methodology and complemented through interviews. Four viewpoints emerged: cooperation through pro-active engagement, cooperation through targeted policies, cooperation through an aligned institutional setup, and cooperation through socio-cultural proximity. Results can inform policy-making aimed to increase stakeholder involvement in participatory approaches in cross-border regions.

Business interaction is important for innovation performance but may be challenging in cross-border regions. The objective of this research was to investigate the relation between factors that define cross-border business interaction and innovativeness. From the cross-border regional innovation systems literature, we operationalized thirty-five factors which potentially influence cross-border business interaction; these factors concern availability of science and knowledge bases, socio-cultural proximity, accessibility, institutional set-up, and governance. We conducted a survey focusing on these factors and analyzed the data using Cronbach’s alpha and linear regression. The cross-border interaction factors identified in the survey results served as independent variables and the differences in innovativeness levels in different European cross-border regions served as our dependent variable. This study confirmed that differences in innovativeness levels between countries can be related to factors hindering cross-border business interaction.

To reduce nutrient losses from the food system, it is necessary to improve biomass management and foster change. Such a change is often hindered by a lack of stakeholder interaction. Therefore, a qualitative case study and a practical application of the innovation platform approach in the Dutch-German border region Rhine-Waal were carried out to determine challenges and opportunities in the agro-food-waste system towards circular nutrient management in a nutrient-saturated and intensive animal production-dominated localized area. Twenty-one actors participated in a half-day workshop. A bottom-up approach was chosen as it increases trust between stakeholders and supports the acceptance of research processes. This study identified opportunities and challenges perceived by stakeholders participating in the innovation platform approach to facilitate a transition towards local circular nutrient management. We observed that challenges and opportunities exist at three levels: the individual actor’s level, the system level and the interconnection of the system with its wider environment. With a variety of stakeholders from animal and crop production to the food processing industry being present in the study area, the current demand and supply of biomass is very diverse. This diversity has been identified as a distinct opportunity for the establishment of a biomass exchange network in the area. However, information on demand and supply of nutrients between actors is currently scattered and information sharing hindered by the lack of direct monetary benefits. The lessons learned using the innovation platform approach are a first step towards improving nutrient circularity at a localized scale in nutrient-saturated areas.