Skin cancer is among the most prevalent cancers globally, emphasizing the need for early detection and accurate diagnosis to improve outcomes. Traditional diagnostic methods, based on visual examination, are subjective, time-intensive, and require specialized expertise. Current artificial intelligence (AI) approaches for skin cancer detection face challenges such as computational inefficiency, lack of interpretability, and reliance on standalone CNN architectures. To address these limitations, this study proposes a comprehensive pipeline combining transfer learning, feature selection, and machine-learning algorithms to improve detection accuracy. Multiple pretrained CNN models were evaluated, with Xception emerging as the optimal choice for its balance of computational efficiency and performance. An ablation study further validated the effectiveness of freezing task-specific layers within the Xception architecture. Feature dimensionality was optimized using Particle Swarm Optimization, reducing dimensions from 1024 to 508, significantly enhancing computational efficiency. Machine-learning classifiers, including Subspace KNN and Medium Gaussian SVM, further improved classification accuracy. Evaluated on the ISIC 2018 and HAM10000 datasets, the proposed pipeline achieved impressive accuracies of 98.5% and 86.1%, respectively. Moreover, Explainable-AI (XAI) techniques, such as Grad-CAM, LIME, and Occlusion Sensitivity, enhanced interpretability. This approach provides a robust, efficient, and interpretable solution for automated skin cancer diagnosis in clinical applications.

Breast cancer stands as a predominant health concern for women globally. As mammography is the primary screening tool for breast cancer detection, improving the detection of breast cancer at screening could save more lives. This mammography review paper comprehensively reviews computer-aided techniques during a specific time frame for the segmentation and classification of microcalcification, evaluating image processing, machine learning, and deep learning techniques. The review is meticulously carried out, adhering closely to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. This article focuses on mammographic breast cancer detection approaches based on automated systems, discussed chronologically from 1970 through 2023. This article encompasses the breadth of artificial intelligence-based methods from the most primitive to the most sophisticated models. Image processing and machine learning-based methods are comprehensively reviewed. Evaluating a deep learning architecture based on self-extracted features for classification tasks demonstrated outstanding performance. Large-scale datasets required for a broader and in-depth analysis of novel methods for breast cancer detection are also discussed in this article. This research work is aligned with the United Nations’ sustainability development goals.

Detecting lung diseases in medical images can be quite challenging for radiologists. In some cases, even experienced experts may struggle with accurately diagnosing chest diseases, leading to potential inaccuracies due to complex or unseen biomarkers. This review paper delves into various datasets and machine learning techniques employed in recent research for lung disease classification, focusing on pneumonia analysis using chest X-ray images. We explore conventional machine learning methods, pretrained deep learning models, customized convolutional neural networks (CNNs), and ensemble methods. A comprehensive comparison of different classification approaches is presented, encompassing data acquisition, preprocessing, feature extraction, and classification using machine vision, machine and deep learning, and explainable-AI (XAI). Our analysis highlights the superior performance of transfer learning-based methods using CNNs and ensemble models/features for lung disease classification. In addition, our comprehensive review offers insights for researchers in other medical domains too who utilize radiological images. By providing a thorough overview of various techniques, our work enables the establishment of effective strategies and identification of suitable methods for a wide range of challenges. Currently, beyond traditional evaluation metrics, researchers emphasize the importance of XAI techniques in machine and deep learning models and their applications in classification tasks. This incorporation helps in gaining a deeper understanding of their decision-making processes, leading to improved trust, transparency, and overall clinical decision-making. Our comprehensive review serves as a valuable resource for researchers and practitioners seeking not only to advance the field of lung disease detection using machine learning and XAI but also from other diverse domains.

A new methodology, the hybrid learning system (HLS), based upon semi-supervised learning is proposed. HLS categorizes hyperspectral images into segmented regions with discriminative features using reduced training size. The technique utilizes the modified breaking ties (MBT) algorithm for active learning and unsupervised learning-based regressors, viz. multinomial logistic regression, for hyperspectral image categorization. The probabilities estimated by multinomial logistic regression for each sample helps towards improved segregation. The high dimensionality leads to a curse of dimensionality, which ultimately deteriorates the performance of remote sensing data classification, and the problem aggravates further if labeled training samples are limited. Many studies have tried to address the problem and have employed different methodologies for remote sensing data classification, such as kernelized methods, because of insensitiveness towards the utilization of large dataset information and active learning (AL) approaches (breaking ties as a representative) to choose only prominent samples for training data. The HLS methodology proposed in the current study is a combination of supervised and unsupervised training with generalized composite kernels generating posterior class probabilities for classification. In order to retrieve the best segmentation labels, we employed Markov random fields, which make use of prior labels from the output of the multinomial logistic regression. The comparison of HLS was carried out with known methodologies, using benchmark hyperspectral imaging (HI) datasets, namely “Indian Pines” and “Pavia University”. Findings of this study show that the HLS yields the overall accuracy of {99.93% and 99.98%}_{Indian Pines} and {99.14% and 99.42%}_{Pavia University} for classification and segmentation, respectively.

Intravascular optical coherence tomography (IVOCT) is emerging as an effective imaging technique for accurately characterizing coronary atherosclerotic plaques. This technique provides detailed information on plaque morphology and composition, enabling the identification of high-risk features associated with coronary artery disease and adverse cardiovascular events. However, despite advancements in imaging technology and image assessment, the adoption of IVOCT in clinical practice remains limited. Manual plaque assessment by experts is time-consuming, prone to errors, and affected by high inter-observer variability. To increase productivity, precision, and reproducibility, researchers are increasingly integrating artificial intelligence (AI)-based techniques into IVOCT analysis pipelines. Machine learning algorithms, trained on labelled datasets, have demonstrated robust classification of various plaque types. Deep learning models, particularly convolutional neural networks, further improve performance by enabling automatic feature extraction. This reduces the reliance on predefined criteria, which often require domain-specific expertise, and allow for more flexible and comprehensive plaque characterization. AI-driven approaches aim to facilitate the integration of IVOCT into routine clinical practice, potentially transforming this technique from a research tool into a powerful aid for clinical decision-making. This narrative review aims to (i) provide a comprehensive overview of AI-based methods for analyzing IVOCT images of coronary arteries, with a focus on plaque characterization, and (ii) explore the clinical translation of AI to IVOCT, highlighting AI-powered tools for plaque characterization currently intended for commercial and/or clinical use. While these technologies represent significant progress, current solutions remain limited in the range of plaque features these methods can assess. Additionally, many of these solutions are confined to specific regulatory or research settings. Therefore, this review highlights the need for further advancements in AI-based IVOCT analysis, emphasizing the importance of additional validation and improved integration with clinical systems to enhance plaque characterization, support clinical decision-making, and advance risk prediction.