Tobias Freitag

Dr. Tobias Freitag

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Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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2 February 2017 in Archives of orthopaedic and trauma surgery
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Journal Article
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KKKarl Philipp Kutzner
Karl Philipp Kutzner
TFTobias Freitag
Tobias Freitag
SDStefanie Donner
Stefanie Donner
MKMark Predrag Kovacevic
Mark Predrag Kovacevic
RBRalf Bieger
Ralf Bieger
Introduction The principle of implanting a calcar-guided short stem consists of an individual alignment alongside the medial calcar providing the ability of reconstructing varus and valgus anatomy in a great variety. However, still, there are broad concerns about the safety of extensive varus and valgus positioning in regard to stability, bony alterations, and periprosthetic fractures. Materials and methods 216 total hip arthroplasties using a calcar-guided short stem (optimys, Mathys Ltd.) in 162 patients were included. Depending on postoperative CCD angle, hips were divided into five groups (A–E). Varus- and valgus tilt and axial subsidence were assessed by “Einzel-Bild-Roentgen-Analyse”(EBRA-FCA, femoral component analysis) over a 2-year follow-up. The incidence of stress-shielding and cortical hypertrophy as well as clinical outcome [Harris Hip Score (HHS)] were reported. Results Postoperative CCD angles ranged from 117.9° to 145.6° and mean postoperative CCD angles in group A–E were 123.3°, 128.0°, 132.4°, 137.5°, and 142.5°, respectively. After 2 years, the mean varus/valgus tilt was −0.16°, 0.37°, 0.48°, 0.01°, and 0.86°, respectively (p = 0.502). Axial subsidence after 2 years was 1.20, 1.02, 1.44, 1.50, and 2.62 mm, respectively (p = 0.043). No periprosthetic fractures occurred and none of the stems had to be revised. Rates of stress-shielding and cortical hypertrophy as well as HHS showed no significant difference between the groups. Conclusions Valgus alignment results in increased subsidence but does not affect the clinical outcome. There is no difference in stress shielding and cortical hypertrophy between the groups. The authors recommend long term monitoring of valgus aligned stems.

7 March 2016 in Journal of Orthopaedic Surgery and Research
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KKKarl Philipp Kutzner
Karl Philipp Kutzner
MKMark Predrag Kovacevic
Mark Predrag Kovacevic
TFTobias Freitag
Tobias Freitag
AFAndreas Fuchs
Andreas Fuchs
HRHeiko Reichel
Heiko Reichel
RBRalf Bieger
Ralf Bieger
Short stems have gained popularity in recent years. Because of encouraging clinical results, indications have been expended from young to elderly and obese patients. However, long-term results are lacking. The purpose of this study was to evaluate the influence of gender, age, body weight, body mass index (BMI), and offset version on short-stem migration in correlation to the clinical outcome. The implant migration of 202 metaphyseal-anchoring, calcar-guided short stems in 151 patients was assessed by “Einzel-Bild-Roentgen-Analyse” femoral component analysis (EBRA-FCA, femoral component analysis) in a 2-year follow-up. Full weight bearing was allowed directly after surgery. Patients were divided into groups regarding gender, age, body weight, BMI, and offset version. The Harris hip score (HHS) and satisfaction on visual analogue scale (VAS) were analyzed. After 2 years, mean axial subsidence of all 202 implants was 1.43 mm (standard deviation, SD 1.45 mm). A continuous reduction of initially pronounced subsidence over time could be observed. None of the stems had to be revised. Statistically significant increased rates of subsidence were seen in male (1.68 mm; SD 1.56 mm; p = 0.005) and heavy patients (1.54 mm; SD 1.48 mm; p = 0.022). No differences in implant migration were found regarding age, BMI, and different offset versions. HHS improved markedly from 45.8 (SD 15.9) to 98.1 (SD 4.7) while satisfaction on VAS improved from 1.8 (SD 2.2) to 9.7 (SD 0.9) after 2 years. The results suggest a migration pattern with initially pronounced subsidence followed by subsequent stabilization. Male and obese patients show a slightly increased initial subsidence without any signs of sustained micromovement. No correlation was found concerning clinical results and pronounced initial subsidence above the threshold of 1.5 mm. No aseptic loosening or other signs of implant failure were seen within the observation period of 2 years. German Clinical Trials Register, DRKS00009834 .

1 November 2020 in Journal of Orthopaedic Science
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Journal Article
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KKKarl Philipp Kutzner
Karl Philipp Kutzner
EREmanuel Ried
Emanuel Ried
SDStefanie Donner
Stefanie Donner
RBRalf Bieger
Ralf Bieger
JPJoachim Pfeil
Joachim Pfeil
TFTobias Freitag
Tobias Freitag
Short-term results of several short-stem designs have indicated early axial migration. Mid- and long-term results for most designs are lacking. The objective of this study was to evaluate the mid-term migration pattern of a calcar-guided short stem five years postoperative. Implant migration of 191 calcar-guided short stems was assessed by Ein-Bild-Roentgen-Analysis Femoral-Component- Analysis (EBRA-FCA) 5 years after surgery. Migration pattern of the whole group was analyzed and compared to the migration pattern of implants potentially being "at hazard" with a subsidence of more than 1.5 mm at 2 years postoperatively. Influence of preoperative Dorr types (A vs. B vs. C), age (70 years), gender (female vs. male), weight (90 kg), BMI (30) and uni-vs. bilateral procedures on mid-term migration pattern was analyzed. Additionally outcome of varus- and valgus stem alignment was assessed. Mean axial subsidence was 1.5 mm (SD 1.48 mm) at final follow-up. Two years after surgery 73 short stems were classified "at hazard". Of these stems, 69 cases showed secondary stabilisation in the following period, whereas 4 cases presented unstable with more than 1 mm of further subsidence. Stem revision was not required neither in the group of implants with early stabilisation nor the group with pronounced early onset migration. Male gender and heavy-weight patients had a significant higher risk for axial migration, as well as extensive valgus stem alignment, whereas for Dorr type B, compared to A, no statistical difference could be observed. In most cases, even in the group of stems being "at hazard", settling could be documented. While different Dorr types did not show a statistically significant impact on axial migration, particularly in male and heavy-weight patients the risk of continuous subsidence is increased. In those 4 cases with further migration, undersizing of the stem could be recognized. At present, clinical consequences are still uncertain.

1 February 2018 in Clinical Biomechanics
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Journal Article
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KKKarl Philipp Kutzner
Karl Philipp Kutzner
TFTobias Freitag
Tobias Freitag
RBRalf Bieger
Ralf Bieger
HRHeiko Reichel
Heiko Reichel
JPJoachim Pfeil
Joachim Pfeil
LDLutz Dürselen
Lutz Dürselen
Short-stem total hip arthroplasty (THA) potentially offers advantages compared to conventional THA, including sparing bone and soft tissue and being a facilitated and less traumatic implantation. However, the indication is limited to patients with sufficient bone quality. Cemented short-stem THA might provide an alternative to conventional cemented THA. To date, no cemented short stem is available on the market. In the present in vitro study, primary stability of a new cemented short stem was evaluated, comparing standard (undersized stem) versus line-to-line (same-sized stem) cementing techniques, using six pairs of human cadaver femurs. Primary stability, including reversible micromotion and irreversible migration, was assessed in a dynamic material-testing machine. Fracture load was tested and fracture pattern analyzed. Both cementation techniques (standard vs. line-to-line) displayed comparable results with respect to primary stability without any statistical differences (micromotion: 17.5 μm vs. 9.6 μm (p = 0.063); migration: 9.5 μm vs. 38.2 μm (p = 0.188)). Regarding fracture load, again, no difference was observed (3670 N vs. 3687 N (p = 0.063)). In all cases, proximal fractures of Vancouver type B3 occurred. The present in vitro study demonstrates that the line-to-line cementation technique, which is favourable regarding the philosophy of short stem THA, can be further pursued in the course of the development of a cemented short stem. Further investigations should address how well the cemented short stem compares to well-established cemented straight-stem designs.

5 July 2016 in Journal of Orthopaedic Surgery and Research
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Journal Article
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RBRalf Bieger
Ralf Bieger
TFTobias Freitag
Tobias Freitag
AIAnita Ignatius
Anita Ignatius
HRHeiko Reichel
Heiko Reichel
LDLutz Dürselen
Lutz Dürselen
The Zweymüller stem design has proven long-term stability with a 20-year survival rate of over 90 %. Primary stability necessitates implant-bone micromotions below 150 μm, otherwise bony ingrowth is negatively influenced. Using fresh paired human femurs, we investigated a modification of the Zweymüller-type stem design with reduced proximal lateral shoulder in reference to primary stability. Relative motion between the implant and the cortical bone as well as the irreversible implant migration was investigated under dynamic loading (100–1600 N) over 100,000 cycles using miniature displacement transducers. Micromotions were below the critical threshold for both implants at all measurement points. Axial reversible and irreversible micromotions were not influenced by reducing the shoulder of the prosthesis. Resistance against rotational moments was less pronounced after reduction of the shoulder without statistical significant results. Reducing the proximal shoulder of the Zweymüller-type stem design does not negatively influence axial stability but might negatively influence rotational stability. Even though, comparable results still suggest a reasonable resistance against rotational forces.

23 March 2021 in Archives of orthopaedic and trauma surgery
Verified
Journal Article
Open access
PDF file
TFTobias Freitag
Tobias Freitag
KKKarl Philipp Kutzner
Karl Philipp Kutzner
RBRalf Bieger
Ralf Bieger
HRHeiko Reichel
Heiko Reichel
AIAnita Ignatius
Anita Ignatius
LDLutz Dürselen
Lutz Dürselen
Purpose: In total hip arthroplasty, uncemented short stems have been used more and more frequently in recent years. Especially for short and curved femoral implants, bone-preserving and soft tissue-sparing properties are postulated. However, indication is limited to sufficient bone quality. At present, there are no curved short stems available which are based on cemented fixation. Methods: In this in vitro study, primary stability and maximum fracture load of a newly developed cemented short-stem implant was evaluated in comparison to an already well-established cemented conventional straight stem using six pairs of human cadaver femurs with minor bone quality. Primary stability, including reversible micromotion and irreversible migration, was assessed in a dynamic material-testing machine. Furthermore, a subsequent load-to-failure test revealed the periprosthetic fracture characteristics. Results: Reversible and irreversible micromotions showed no statistical difference between the two investigated stems. All short stems fractured under maximum load according to Vancouver type B3, whereas 4 out of 6 conventional stems suffered a periprosthetic fracture according to Vancouver type C. Mean fracture load of the short stems was 3062 N versus 3160 N for the conventional stems (p = 0.84). Conclusion: Primary stability of the cemented short stem was not negatively influenced compared to the cemented conventional stem and no significant difference in fracture load was observed. However, a clear difference in the fracture pattern has been identified.