Mihai Grigoroscuta

Dr. Mihai Grigoroscuta

National Institute of Materials Physics
orcid

Research Focus & Metrics

Academic Career Length

7Years (2020-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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27 November 2024 in Materials
Verified
Journal Article
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Doina- Antonia MercanDoina- Antonia Mercan
Doina- Antonia Mercan
Adelina-Gabriela NiculescuAdelina-Gabriela Niculescu
Adelina-Gabriela Niculescu
ABAda Birca
Ada Birca
Cristea Diana-ElenaCristea Diana-Elena
Cristea Diana-Elena
AMAlina Moroșan
Alina Moroșan
Alexandru Mihai GrumezescuAlexandru Mihai Grumezescu
Alexandru Mihai Grumezescu
Iron oxide nanoparticles were synthesized using a vortex microfluidic system and subsequently functionalized with a primary shell of salicylic acid, recognized for its ability to increase the stability and biocompatibility of coated materials. In the second stage, the vortex platform was placed in a magnetic field to facilitate the growth and development of a porous silica shell. The selected drug for this study was micafungin, an antifungal agent well regarded for its effectiveness in combating fungal infections and identified as a priority compound by the World Health Organization (WHO). The resulting nanocomposite system was characterized using various techniques, including Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), transmission electron microscopy (TEM), dynamic light scattering (DLS), Brunauer–Emmett–Teller (BET) analysis, UV-Vis spectroscopy, and Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS). The synthesis method produced nanoparticles with dimensions of 5–7 nm, highlighting the advantages of the chosen approach. A desorption profile was established using a continuous-flow, UV-Vis analysis system, indicating that the bioactive compound was released slowly; after two hours, approximately 50% of the loaded micafungin was detected in the release medium. Furthermore, the results obtained from the FT-ICR MS analysis provided molecular-level confirmation, thereby supporting the release mechanism of micafungin from the nanosystem.

8 October 2023 in Metals
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Journal Article
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ISIevgen Solodkyi
Ievgen Solodkyi
VPVadym Petrusha
Vadym Petrusha
MGMihai Grigoroscuta
Mihai Grigoroscuta
JSJanett Schmelzer
Janett Schmelzer
GHGeorg Hasemann
Georg Hasemann
MKManja Krüger
Manja Krüger
Mo matrix composites (MMC) with Mo-9Si-8B inclusions were fabricated by pressure-less sintering (PLS) and spark plasma sintering (SPS) techniques at temperatures between 1200–1500 °C using 1 wt.% Ni sinter additive. The positive impact of the addition Ni addition on the sinterability and formation of a continuous Mo matrix of MMC with randomly distributed Mo3Si and Mo5SiB2 inclusions was determined. The Ni addition increased the shrinkage of MMC during PLS by almost a third. The continuous Mo matrix of MMC and a relative density of more than 98% was obtained after SPS at 1400–1500 °C. The composite with the maximum relative density of 98% showed a Vickers hardness of 482 ± 9 (HV20). The potential of using Ni-activated PLS and SPS to produce high-density MMC is shown.

17 August 2021 in Molecules
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SANTANU KUMAR PADHISANTANU KUMAR PADHI
SANTANU KUMAR PADHI
Nicoletta BaglieriNicoletta Baglieri
Nicoletta Baglieri
VBValentina Bonino
Valentina Bonino
AAAngelo Agostino
Angelo Agostino
LOLorenza Operti
Lorenza Operti
MTMarco Truccato
Marco Truccato
We report for the first time on the antimicrobial activity of MgB2 powders produced via the Reactive Liquid Infiltration (RLI) process. Samples with MgB2 wt.% ranging from 2% to 99% were obtained and characterized, observing different levels of grain aggregation and of impurity phases. Their antimicrobial activity was tested against Staphylococcus aureus ATCC BAA 1026, Enterococcus faecalis ATCC 29212, Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, and Candida albicans ATCC 10231. A general correlation is observed between the antibacterial activity and the MgB2 wt.%, but the sample microstructure also appears to be very important. RLI-MgB2 powders show better performances compared to commercial powders against microbial strains in the planktonic form, and their activity against biofilms is also very similar.

1 June 2020 in Journal of Physics: Conference Series
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KYK Yokoyama
K Yokoyama
TOTetsuo Oka
Tetsuo Oka
Kévin BergerKévin Berger
Kévin Berger
RDRémi Dorget
Rémi Dorget
MKMichael Rudolf Koblischka
Michael Rudolf Koblischka
MMM Murakami
M Murakami
MgB2 bulk superconductors are expected to be utilized as rare-earth-free and lightweight trapped field magnets. However, the flux jumps frequently happen during the magnetizing processes, and heavily degrade the field-trapping performances. We have investigated the effect of additives to the MgB2 bulk samples prepared by spark plasma sintering process, and observed various flux jumps during the pulsed field magnetizing processes, which were carried out at 14 K which was obtained by the 2-stage GM cryocooler. The authors classified the flux motions as three categories as “no flux flow”, “fast flux flow”, and “flux jump” regions, and investigated the conditions where the flux jumps happen. We observed some drastic flux jumps in the pristine and clarified the effect of graphene addition to the flux jumps. The experimental results showed us a possible expansion of no flux jump region, and suggested us the improvement of field trapping capability.

6 October 2021 in Molecules
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Journal Article
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PBPetre Badica
Petre Badica
DBDan Batalu
Dan Batalu
Carmen ChifiriucCarmen Chifiriuc
Carmen Chifiriuc
MBMihail Burdusel
Mihail Burdusel
MGMihai Grigoroscuta
Mihai Grigoroscuta
MTMarco Truccato
Marco Truccato
Pristine high-density bulk disks of MgB2 with added hexagonal BN (10 wt.%) were prepared using spark plasma sintering. The BN-added samples are machinable by chipping them into desired geometries. Complex shapes of different sizes can also be obtained by the 3D printing of polylactic acid filaments embedded with MgB2 powder particles (10 wt.%). Our present work aims to assess antimicrobial activity quantified as viable cells (CFU/mL) vs. time of sintered and 3D-printed materials. In vitro antimicrobial tests were performed against the bacterial strains Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, Staphylococcus aureus ATCC 25923, Enterococcus faecium DSM 13590, and Enterococcus faecalis ATCC 29212; and the yeast strain Candida parapsilosis ATCC 22019. The antimicrobial effects were found to depend on the tested samples and microbes, with E. faecium being the most resistant and E. coli the most susceptible.

1 August 2022 in Journal of Magnesium and Alloys
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Journal Article
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MGMihai Grigoroscuta
Mihai Grigoroscuta
GAG.V. Aldica
G.V. Aldica
MBM. Burdusel
M. Burdusel
Viorel SanduViorel Sandu
Viorel Sandu
AKA. Kuncser
A. Kuncser
PBP. Badica
P. Badica