Currently, there is no comprehensive bibliometric study in the literature on Crohn’s disease (CD). The aim of this study was to analyze articles published on CD using bibliometric and statistical methods. The aim was to identify current research trends, show global productivity, and determine important players such as countries, journals, institutions, and authors. A total of 16,216 articles published on CD between 1980 and 2022 were analyzed using various statistical and bibliometric methods. Bibliometric network visualization maps were used to perform trend topic analysis, citation analysis, and international collaboration analysis. Spearman’s correlation coefficient was used for correlation analysis. The top 3 contributing countries to the literature were the United States of America (USA) (n = 4344, 26.7%), the United Kingdom (UK) (n = 2036, 12.5%) and Germany (n = 1334, 8.2%). The most active institutions were Udice French Research Universities (n = 696), Assistance Publique Hopitaux Paris (n = 570), and Institut National de la Sante et de la Recherche Medicale Inserm (n = 479). The most productive journals were Inflammatory Bowel Diseases (n = 1100), Journal of Crohn’s & Colitis (n = 579), and Gut (n = 510). The most prolific author was Colombel JF. (n = 290). The most frequently researched topics from past to present included infliximab, ulcerative colitis, surgery, pediatrics, adalimumab, magnetic resonance imaging, inflammation, perianal CD/perianal fistula, azathioprine, magnetic resonance enterography, small bowel, stricture/strictureplasty, recurrence, therapy/treatment, ustekinumab, mucosal healing, biomarkers, fistula, quality of life, ultrasonography, epidemiology, capsule endoscopy, laparoscopic surgery/laparoscopy, endoscopy, disease activity, postoperative recurrence, and the Nucleotide Binding Oligomerization Domain Containing 2 gene. We have seen an exponential increase in worldwide publications on CD. In recent years, the major research topics related to CD have been ustekinumab, vedolizumab, fecal calprotectin, therapeutic drug monitoring, biologics, biomarkers, exclusive enteral nutrition, microbiome/microbiota, magnetic resonance enterography, anti-TNF, postoperative complications, and mucosal healing. We determined that countries with large economies, particularly the United States, United Kingdom, Germany, France, Canada, Italy, Japan and China, have taken the lead in research contributions to the development of CD literature.

Aim: With the Coronavirus Disease 2019 (COVID-19) pandemic starting in late 2019 and continuing into 2020, permanent or periodic quarantine processes and curfews have been implemented. The objective of the study was to investigate the impact of extended quarantine processes during the pandemic on the development of metabolic syndrome (MET-S) due to physical inactivity. Material and Method: This retrospective study consists of two groups. The first group consists of patients who applied to our hospital in the 12 months preceding the pandemic. The second group consists of the same patients who applied to the same hospital within 12 months of the onset of the pandemic. A total of 44,024 participants who had lab data prior to and during the pandemic were included in the study. Fasting plasma glucose (FPG), Triglyceride (TRIG), Total Cholesterol (T-Chol), High Density Lipoprotein-Cholesterol (HDL-C), Low Density Lipoprotein-Cholesterol (LDL-C) levels and demographic characteristics of the patients were recorded. The test averages were compared between the two groups and their effects on the development of MET-S were subjected to statistical analysis. Results: When we compared our patients' HDL-C, FPG and TRIG levels measured during the pandemic and the pre-pandemic period, we found a statistically significant increase (p100 mg/dL and TRIG>150 mg/dL during the pandemic was statistically significantly higher than during the pre-pandemic period (51.7% vs 45.8%, p

Amaç: Aromaterapi bitkilerin kök, yaprak veya çiçeğini damıtarak elde edilen yağların hastalıkları önlemek ve oluşmuş olan hastalıkları da tedavi etmek amacı ile kullanılmasıdır. Literatür taramasında bu konuda bibliyometrik bir araştırmaya rastlanmamıştır. Bu nedenle, bilimsel makaleleri bütünsel olarak analiz etmeyi ve küresel verimlilik ve trend konularını ortaya çıkarmayı amaçladık. Gereç ve Yöntem: Bu çalışmada, Web of Science veri tabanından aromaterapi ile ilgili yayınlanmış 1428 makale (1985-2019) istatistiksel olarak analiz edilmiştir. Trend konularını, atıf analizlerini ve ülkeler arası işbirliklerini ortaya çıkarmak için bibliyometrik ağ görselleştirme haritaları oluşturulmuştur. Bulgular : Amerika Birleşik Devletleri 316 yayın (%22,1) ile aromaterapi literatüründe birinci oldu. İngiltere, Japonya, İran ve Avustralya yayın sayıları ile ABD takip etti (sırasıyla 143,136, 126, 74). Complementary Therapies in Medicine (50 makale), Journal Of Alternative And Complementary Medicine (47 makale) ve Evidence-Based Complementary And Alternative Medicine (36 makale) en üretken ilk 3 dergidir. Hur Mh (18 makale) en aktif yazar, Unıversity Of London (32 makale) en aktif kurumdur. Aromaterapi literatüründe en çok alıntı yapılan makale Edris tarafından yayımlanan “Pharmaceutical and therapeutic potentials of essential oils and their individual volatile constituents: A review” oldu. Aromaterapi çalışmalarında kullanılan en trend bitkilerin 111 çalışmada kullanılan Lavanta bitkisi, daha sonra sırayla, Lanalol 16, Bergamot 16, ve 12 yayında da peppermint bitkisinin olduğu gösterilmiştir. Sonuç : Aramoterapi tıbbın birçok alanında kullanım alanı olduğunu ve küresel olarak uluslararası önemli işbirlikler sayesinde bir çok dünya ülkesinde tedavi amaçlı kullanıldığı gösterilmiştir.

Purpose: Many noninvasive tests have been studied for the diagnosis and determining the liver fibrosis score. In this study, we aimed to research the correlation of platelet parameters and stage of liver fibrosis in patients with chronic hepatitis B (CHB).Materials and Methods: A total of 140 biopsy-proven naive CHB cases were included in the study. HBV-DNA level, liver enzymes and function tests, white blood cell count, platelet parametres, hemoglobin, histological activity index (HAI) and other routine biochemical parameters were tested. Patients were divided into two groups as F0-2 and F3-6 with Ishak scoring system according to the severity of liver fibrosis.Results: There was no significant difference between the groups F0-2 and F3-6 in terms of, platelet (PLT), mean platelet volume (MPV), platelet distribution width (PDW) and plateletcrit (PCT). There was a significant difference between these two groups for HAI, aspartate aminotransferase (AST), gamma glutamyl transpeptidase (GGT), age and lymphocyte (LYM) parameters. The formulation of (AST x Age x LYM) / √PLT)which was formed from many different combinations, was investigated in order to be used in predicting the liver fibrosis stage. Conclusion: Although our new index is more sensitivitythan other noninvasive scoring systems, it is needed to have a larger sample size in patients with severe stage liver fibrosis in order to be used safely as a noninvasive marker.