Cellular immune responses, particularly those associated with CD3⁺CD8⁺ cytotoxic T lymphocytes (CTL), are critical factors in controlling viral infection. Nasopharyngeal carcinoma (NPC) is closely associated with persistent Epstein-Barr virus (EBV) infection. NPC vaccine studies have focused on enhancing specific antiviral CTL responses. In this study, three vaccines capable of expressing the EBV-latent membrane protein 2 (LMP2) (a DNA vector, an adeno-associated virus (AAV) vector, and a replication-defective adenovirus serotype 5 (Ad5) vector) were respectively used to immunize female Balb/c mice (4–6 weeks old) at weeks 0, 2 and 4, either alone or in combination. Our results suggest that combined immunization with DNA, AAV, and adenovirus vector vaccines induced specific cellular immunity more effectively than any of these vectors alone or a combination of two of the three, constituting a sound vaccine strategy for the prevention and treatment of NPC.

Predicting flight delays plays a critical role in reducing financial losses and increasing passenger satisfaction. Due to their ability to combine multiple algorithms, ensemble methods have demonstrated strong predictive performance in many research fields. In this paper, ensemble methods are adopted to predict flight delays. First, based on the current studies, two novel explanatory variables, named arrival/departure pressure and cruise pressure, are proposed as factors affecting flight delays. Second, we introduce the ensemble methods and select representative algorithms for the prediction problem. In addition to the ensemble methods, classical algorithms are also used to predict flight delays. Finally, the actual operational data of Beijing Capital International Airport were utilized to conduct a case study. The results show that the stacking method has better prediction performance than other baseline methods. The mean absolute error (MAE) of the stacking method was about 12.58 min on the test dataset. Furthermore, we tested the effect of the two explanatory variables proposed in this paper, and the results show that the MAE was reduced by about 20% by using the stacking method.

Airport environmental carrying capacity (AECC) provides the fundamental conditions for airport development and operation activities. The prediction of AECC is a necessary condition for planning an appropriate development mode for the airport. This paper studies the dynamic prediction method of the AECC to explore the development characteristics of AECC in different airports. Based on the driving force-pressure-state-response (DPSR) framework, the method selects 17 main variables from economic, social, environmental and operational dimensions, and then combines the drawing of causal loop diagrams and the establishment of system flow diagrams to construct the system dynamics (SD) model of AECC. The predicted values of AECC are obtained through SD model simulation and accelerated genetic algorithm projection pursuit (AGA-PP) model calculation. Considering sustainable development needs, different scenarios are set to analyze the appropriate development mode of the airport. The case study of the Pearl River Delta airports resulted in two main conclusions. First, in the same economic zone, different airports with similar aircraft movements have similar development characteristics of AECC. Second, the appropriate development modes for different airports are different, and the appropriate development modes for the airport in different periods are also different. The case study also proves that the AECC prediction based on SD model and AGA-PP model can realize short-term policy formulation and long-term planning for the airport development mode, and provide decision-making support for relevant departments of airport.

Since existing studies primarily explore green development measures from the static perspective of a single airport stakeholder, this paper constructs an evolutionary game model to analyze the strategic choices of three key stakeholders: airport authorities, third-party organizations, and government departments, based on evolutionary game theory. By solving the stable strategy of the tripartite evolution using the Jacobian matrix, the green transition of airport development can be divided into three stages: “initiation”, “development”, and “maturity”, allowing for the exploration of key factors influencing the green transition of airport development. A simulation analysis is conducted based on real Guangzhou Baiyun International Airport data. The results indicate that the tripartite evolutionary game strategy is stable at $E_4(0,0,1)$ and the green transition of Baiyun Airport remains in the development stage. By improving the reward and punishment mechanisms of government departments, the evolutionary game strategy can be stabilized at $E_8(1,1,1)$, promoting the green transition of airport development toward the mature stage. By adjusting the game parameters, the dynamic process of green transition in airports at different levels of development and under varying regulatory environments can be effectively captured, supporting the precise formulation of corresponding policies.

In order to clarify the comprehensive operational capabilities of the airport and better plan the sustainable development mode of the airport, this paper studies the evaluation method of airport environmental carrying capacity. First, this paper proposes the concept of airport environmental carrying capacity by taking into account the complex characteristics of airports affected by multiple factors and then selects 16 representative evaluation indicators to construct an indicator system based on the Driving Force-Pressure-State-Response (DPSR) framework. Finally, the accelerated genetic algorithm-projection pursuit model is established to model a comprehensive evaluation index, which is used to calculate the airport environmental carrying capacity (AECC). The results of the case study show that the AECC of Guangzhou Baiyun International Airport (CAN) decreased year by year from 2008 to 2017, which is in line with the coordinated development level of CAN. By analysing the changing mechanism of AECC and indicators, we get 6 key influencing indicators that led to the continuous decline of AECC and put forward some political suggestions to improve the AECC.

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