Cornel Sieber

Prof. Dr. Cornel Sieber

1. Institute for Biomedicine of Aging, Friedrich-Alexander-Universität Erlangen Nürnberg, Erlangen, Germany
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Research Focus & Metrics

Academic Career Length

39Years (1988-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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24 September 2018 in Age and Ageing
Verified
Journal Article
Open access
PDF file
ACAlfonso J. Cruz-Jentoft
Alfonso J. Cruz-Jentoft
GBGülistan Bahat
Gülistan Bahat
JBJürgen Bauer
Jürgen Bauer
YBYves Boirie
Yves Boirie
OBOlivier Bruyère
Olivier Bruyère
JSJos Schols
Jos Schols
In 2010, the European Working Group on Sarcopenia in Older People (EWGSOP) published a sarcopenia definition that aimed to foster advances in identifying and caring for people with sarcopenia. In early 2018, the Working Group met again (EWGSOP2) to update the original definition in order to reflect scientific and clinical evidence that has built over the last decade. This paper presents our updated findings. to increase consistency of research design, clinical diagnoses and ultimately, care for people with sarcopenia. sarcopenia is a muscle disease (muscle failure) rooted in adverse muscle changes that accrue across a lifetime; sarcopenia is common among adults of older age but can also occur earlier in life. In this updated consensus paper on sarcopenia, EWGSOP2: (1) focuses on low muscle strength as a key characteristic of sarcopenia, uses detection of low muscle quantity and quality to confirm the sarcopenia diagnosis, and identifies poor physical performance as indicative of severe sarcopenia; (2) updates the clinical algorithm that can be used for sarcopenia case-finding, diagnosis and confirmation, and severity determination and (3) provides clear cut-off points for measurements of variables that identify and characterise sarcopenia. EWGSOP2's updated recommendations aim to increase awareness of sarcopenia and its risk. With these new recommendations, EWGSOP2 calls for healthcare professionals who treat patients at risk for sarcopenia to take actions that will promote early detection and treatment. We also encourage more research in the field of sarcopenia in order to prevent or delay adverse health outcomes that incur a heavy burden for patients and healthcare systems.

1 May 2011 in Journal of the American Medical Directors Association
Verified
Journal Article
Closed access
RFRoger Fielding
Roger Fielding
BVBruno Vellas
Bruno Vellas
WEWilliam J. Evans
William J. Evans
SBShalender Bhasin
Shalender Bhasin
JMJohn E. Morley
John E. Morley
MZMauro Zamboni
Mauro Zamboni

13 May 2019 in Age and Ageing
Verified
Journal Article
Open access
PDF file
ACAlfonso J. Cruz-Jentoft
Alfonso J. Cruz-Jentoft
GBGϋlistan Bahat
Gϋlistan Bahat
JBJϋrgen Bauer
Jϋrgen Bauer
YBYves Boirie
Yves Boirie
OBOlivier Bruyère
Olivier Bruyère
MZMauro Zamboni
Mauro Zamboni

1 August 2013 in Journal of the American Medical Directors Association
Verified
Journal Article
Open access
JBJürgen Bauer
Jürgen Bauer
GBGianni Biolo
Gianni Biolo
TCTommy Cederholm
Tommy Cederholm
Matteo  CesariMatteo Cesari
Matteo Cesari
ACAlfonso J. Cruz-Jentoft
Alfonso J. Cruz-Jentoft
YBYves Boirie
Yves Boirie
New evidence shows that older adults need more dietary protein than do younger adults to support good health, promote recovery from illness, and maintain functionality. Older people need to make up for age-related changes in protein metabolism, such as high splanchnic extraction and declining anabolic responses to ingested protein. They also need more protein to offset inflammatory and catabolic conditions associated with chronic and acute diseases that occur commonly with aging. With the goal of developing updated, evidence-based recommendations for optimal protein intake by older people, the European Union Geriatric Medicine Society (EUGMS), in cooperation with other scientific organizations, appointed an international study group to review dietary protein needs with aging (PROT-AGE Study Group). To help older people (>65 years) maintain and regain lean body mass and function, the PROT-AGE study group recommends average daily intake at least in the range of 1.0 to 1.2 g protein per kilogram of body weight per day. Both endurance- and resistance-type exercises are recommended at individualized levels that are safe and tolerated, and higher protein intake (ie, ≥ 1.2 g/kg body weight/d) is advised for those who are exercising and otherwise active. Most older adults who have acute or chronic diseases need even more dietary protein (ie, 1.2-1.5 g/kg body weight/d). Older people with severe kidney disease (ie, estimated GFR <30 mL/min/1.73 m(2)), but who are not on dialysis, are an exception to this rule; these individuals may need to limit protein intake. Protein quality, timing of ingestion, and intake of other nutritional supplements may be relevant, but evidence is not yet sufficient to support specific recommendations. Older people are vulnerable to losses in physical function capacity, and such losses predict loss of independence, falls, and even mortality. Thus, future studies aimed at pinpointing optimal protein intake in specific populations of older people need to include measures of physical function.

1 February 2017 in Clinical Nutrition
Verified
Journal Article
Closed access
TCT. Cederholm
T. Cederholm
RBRocco Barazzoni
Rocco Barazzoni
PAP. Austin
P. Austin
PBP. Ballmer
P. Ballmer
GBGianni Biolo
Gianni Biolo
PSPierre Singer
Pierre Singer

30 October 2009 in The Journal of nutrition, health and aging
Verified
Journal Article
Open access
PDF file
MKM. J. Kaiser
M. J. Kaiser
JBJ. M. Bauer
J. M. Bauer
CRC. Ramsch
C. Ramsch
WUW. Uter
W. Uter
YGY. Guigoz
Y. Guigoz
MGMNA-International Group
MNA-International Group
To validate a revision of the Mini Nutritional Assessment short-form (MNA®-SF) against the full MNA, a standard tool for nutritional evaluation.