Lucas Mösch

Mr. Lucas Mösch

Universitätsklinikum Aachen, Aachen, North Rhine-Westphalia, Germany
orcid

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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16 November 2022 in Sensors
Verified
Journal Article
Open access
PDF file
Janosch KunczikJanosch Kunczik
Janosch Kunczik
KHKerstin Hubbermann
Kerstin Hubbermann
Lucas MöschLucas Mösch
Lucas Mösch
AFAndreas Follmann
Andreas Follmann
MCMichael Czaplik
Michael Czaplik
Carina Barbosa PereiraCarina Barbosa Pereira
Carina Barbosa Pereira
The ability to continuously and unobtrusively monitor and classify breathing patterns can be very valuable for automated health assessments because respiration is tightly coupled to many physiological processes. Pathophysiological changes in these processes often manifest in altered breathing patterns and can thus be immediately detected. In order to develop a breathing pattern monitoring system, a study was conducted in which volunteer subjects were asked to breathe according to a predefined breathing protocol containing multiple breathing patterns while being recorded with color and thermal cameras. The recordings were used to develop and compare several respiratory signal extraction algorithms. An algorithm for the robust extraction of multiple respiratory features was developed and evaluated, capable of differentiating a wide range of respiratory patterns. These features were used to train a one vs. one multiclass support vector machine, which can distinguish between breathing patterns with an accuracy of 95.79 %. The recorded dataset was published to enable further improvement of contactless breathing pattern classification, especially for complex breathing patterns.

7 September 2023 in PLOS ONE
Verified
Journal Article
Open access
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Lucas MöschLucas Mösch
Lucas Mösch
JKJanosch Kunczik
Janosch Kunczik
LBLukas Breuer
Lukas Breuer
DMDorit Merhof
Dorit Merhof
PGPeter Gass
Peter Gass
CPCarina Barbosa Pereira
Carina Barbosa Pereira
This study presents a novel concept for a smart home cage design, tools, and software used to monitor the physiological parameters of mice and rats in animal-based experiments. The proposed system focuses on monitoring key clinical parameters, including heart rate, respiratory rate, and body temperature, and can also assess activity and circadian rhythm. As the basis of the smart home cage system, an in-depth analysis of the requirements was performed, including camera positioning, imaging system types, resolution, frame rates, external illumination, video acquisition, data storage, and synchronization. Two different camera perspectives were considered, and specific camera models, including two near-infrared and two thermal cameras, were selected to meet the requirements. The developed specifications, hardware models, and software are freely available via GitHub. During the first testing phase, the system demonstrated the potential of extracting vital parameters such as respiratory and heart rate. This technology has the potential to reduce the need for implantable sensors while providing reliable and accurate physiological data, leading to refinement and improvement in laboratory animal care.

7 March 2023 in Bioengineering
Verified
Journal Article
Open access
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Lucas MöschLucas Mösch
Lucas Mösch
IBIsabelle Barz
Isabelle Barz
AMAnna Mueller
Anna Mueller
Carina Barbosa PereiraCarina Barbosa Pereira
Carina Barbosa Pereira
DMDieter Moormann
Dieter Moormann
AFAndreas Follmann
Andreas Follmann
The ability to use drones to obtain important vital signs could be very valuable for emergency personnel during mass-casualty incidents. The rapid and robust remote assessment of heart rates could serve as a life-saving decision aid for first-responders. With the flight sensor data of a specialized drone, a pipeline was developed to achieve a robust, non-contact assessment of heart rates through remote photoplethysmography (rPPG). This robust assessment was achieved through adaptive face-aware exposure and comprehensive de-noising of a large number of predicted noise sources. In addition, we performed a proof-of-concept study that involved 18 stationary subjects with clean skin and 36 recordings of their vital signs, using the developed pipeline in outdoor conditions. In this study, we could achieve a single-value heart-rate assessment with an overall root-mean-squared error of 14.3 beats-per-minute, demonstrating the basic feasibility of our approach. However, further research is needed to verify the applicability of our approach in actual disaster situations, where remote photoplethysmography readings could be impacted by other factors, such as blood, dirt, and body positioning.

12 July 2024 in International Journal of Neural Systems
Verified
Journal Article
Closed access
ERErik Roecher
Erik Roecher
Lucas MöschLucas Mösch
Lucas Mösch
JZJana Zweerings
Jana Zweerings
FTFrank Thiele
Frank Thiele
SCSvenja Caspers
Svenja Caspers
KMKlaus Mathiak
Klaus Mathiak

7 June 2023 in Animals
Verified
Journal Article
Open access
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LBLukas Breuer
Lukas Breuer
Lucas MöschLucas Mösch
Lucas Mösch
Janosch KunczikJanosch Kunczik
Janosch Kunczik
VBVerena Buchecker
Verena Buchecker
HPHeidrun Potschka
Heidrun Potschka
Carina Barbosa PereiraCarina Barbosa Pereira
Carina Barbosa Pereira
Animal research has always been crucial for various medical and scientific breakthroughs, providing information on disease mechanisms, genetic predisposition to diseases, and pharmacological treatment. However, the use of animals in medical research is a source of great controversy and ongoing debate in modern science. To ensure a high level of bioethics, new guidelines have been adopted by the EU, implementing the 3R principles to replace animal testing wherever possible, reduce the number of animals per experiment, and refine procedures to minimize stress and pain. Supporting these guidelines, this article proposes an improved approach for unobtrusive, continuous, and automated monitoring of the respiratory rate of laboratory rats. It uses the cyclical expansion and contraction of the rats’ thorax/abdominal region to determine this physiological parameter. In contrast to previous work, the focus is on unconstrained animals, which requires the algorithms to be especially robust to motion artifacts. To test the feasibility of the proposed approach, video material of multiple rats was recorded and evaluated. High agreement was obtained between RGB imaging and the reference method (respiratory rate derived from electrocardiography), which was reflected in a relative error of 5.46%. The current work shows that camera-based technologies are promising and relevant alternatives for monitoring the respiratory rate of unconstrained rats, contributing to the development of new alternatives for a continuous and objective assessment of animal welfare, and hereby guiding the way to modern and bioethical research.

18 December 2021 in Sensors
Verified
Journal Article
Open access
PDF file
DPDiana Queiros Pokee
Diana Queiros Pokee
Carina Barbosa PereiraCarina Barbosa Pereira
Carina Barbosa Pereira
Lucas MöschLucas Mösch
Lucas Mösch
AFAndreas Follmann
Andreas Follmann
MCMichael Czaplik
Michael Czaplik
In a disaster scene, triage is a key principle for effectively rescuing injured people according to severity level. One main parameter of the used triage algorithm is the patient’s consciousness. Unmanned aerial vehicles (UAV) have been investigated toward (semi-)automatic triage. In addition to vital parameters, such as heart and respiratory rate, UAVs should detect victims’ mobility and consciousness from the video data. This paper presents an algorithm combining deep learning with image processing techniques to detect human bodies for further (un)consciousness classification. The algorithm was tested in a 20-subject group in an outside environment with static (RGB and thermal) cameras where participants performed different limb movements in different body positions and angles between the cameras and the bodies’ longitudinal axis. The results verified that the algorithm performed better in RGB. For the most probable case of 0 degrees, RGB data obtained the following results: Mathews correlation coefficient (MMC) of 0.943, F1-score of 0.951, and precision-recall area under curve AUC (PRC) score of 0.968. For the thermal data, the MMC was 0.913, F1-score averaged 0.923, and AUC (PRC) was 0.960. Overall, the algorithm may be promising along with others for a complete contactless triage assessment in disaster events during day and night.