A systematic review and meta-analysis was performed to analyze the survival of onlay restorations in the posterior region, their clinical behavior according to the material used (ceramic reinforced with lithium disilicate, conventional feldspathic ceramic or reinforced with leucite; hybrid materials and composite), possible complications, and the factors influencing restoration success. The systematic review was based on the preferred reporting items for systematic reviews and meta-analyses (PRISMA) statement, without publication date or language restrictions. An electronic search was made in the PubMed, Scopus, Embase, and Cochrane databases. After discarding duplicate publications and studies that failed to meet the inclusion criteria, the articles were selected based on the population, intervention, comparison, outcome (PICO) question. The following variables were considered in the qualitative and quantitative analyses: restoration survival rate (determined by several clinical parameters), the influence of the material used upon the clinical behavior of the restorations, and the complications recorded over follow-up. A total of 29 articles were selected for the qualitative analysis and 27 for the quantitative analysis. The estimated restoration survival rate was 94.2%. The predictors of survival were the duration of follow-up (beta = −0.001; p = 0.001) and the onlay material used (beta = −0.064; p = 0.028). Composite onlays were associated with a lower survival rate over time. Onlays are a good, conservative, and predictable option for restoring dental defects in the posterior region, with a survival rate of over 90%. The survival rate decreases over time and with the use of composite as onlay material.

Background: The aim of this systematic review and meta-analysis was to determine the fracture resistance and survival rate of partial indirect restorations inlays, onlays, and overlays fabricated using computer-aided design and computer-aided manufacturing (CAD-CAM) technology from ceramics, composite resin, resin nanoceramic, or hybrid ceramic and to analyze the influence of proximal box elevation on fracture resistance. Materials and methods: This systematic review was based on guidelines proposed by the preferred reporting items for systematic reviews and meta-analyses (PRISMA). An electronic search was conducted in databases US National Library of Medicine National Institutes of Health (PubMed), Scopus, Web of Science (WOS), and Embase. In vitro trials published during the last 10 years were included in the review. Results: Applying inclusion criteria based on the review’s population, intervention, comparison, outcome (PICO) question, 13 articles were selected. Meta-analysis by restoration type estimated the fracture resistance of inlays to be 1923.45 Newtons (N); of onlays 1644 N and of overlays 1383.6 N. Meta-analysis by restoration material obtained an estimated fracture resistance for ceramic of 1529.5 N, for composite resin of 1600 Ne, for resin nanoceramic 2478.7 N, and hybrid ceramic 2108 N. Conclusions: Resin nanoceramic inlays present significantly higher fracture resistance values. Proximal box elevation does not exert any influence on the fracture resistance of indirect restorations.

To evaluate the clinicaland biological behavior of full coverage restorations on teeth prepared without finish line during a 4-year follow-up. This prospective study included 149 teeth treated using biologically oriented preparation technique (BOPT). The sample (149 teeth) was divided into two groups: Seventy four teeth restored with crowns, and 75 teeth supporting fixed partial dentures (FPD). Restorations were fabricated with zirconium oxide cores and ceramic coverings. Patients attended regular annual check-ups when probe depth, presence of inflammation with bleeding on probing, presence of plaque, gingival thickness, marginal stability, biological or mechanical complications, and the patient's level of satisfaction were registered over a 4-year follow-up. After the 4-year follow-up, 2.1% of teeth underwent increases in probing depth; 12% of the sample presented inflammation and bleeding on probing; 20% of the restored teeth presented plaque; gingival thickening increased a 32.5%; 98.6% of teeth presented marginal stability; the restoration survival rate was 96.6%, with 2% of biological complications and 1.4% of mechanical complications. General satisfaction score was 80.73. Restorations placed on teeth prepared using BOPT present good periodontal behavior, increase of gingival thickening, and marginal stability over a 4-year follow-up. High survival rates after 4 years show that the technique produces predictable outcomes. The BOPT technique is a good treatment option in cases where replacement of an old restoration is required; presenting good periodontal behavior, gingival thickening, and marginal stability.

M. Fernanda Sol?-Ruiz, DDS, PhD, MD/Elena Lagos-Flores, DDS/Juan Luis Rom?n-Rodriguez, DDS, PhD/Jaime Del Rio Highsmith, DDS, PhD, MD/Antonio Fons-Font, DDS, PhD, MD/Maria Granell-Ruiz, DDS, PhD: Purpose: The aim of this prospective study was to evaluate the clinical efficacy and long-term survival rate of three-unit fixed partial dentures (FPDs) made from lithium disilicate?based core ceramic. Materials and Methods: Twenty-one threeunit FPDs were placed in 19 patients to replace single lost teeth in the esthetic area, following a study protocol that took clinical, esthetic, and radiologic aspects into consideration. Each case was reviewed at 1 week following placement, at 6 months, and then annually for 10 years. Statistical analysis was performed using Kaplan- Meier survival analysis. Results: Out of the 19 patients, 14.3% presented reversible postoperative sensitivity. Recession was observed in 24% of dental posts, and 7.1% presented marginal discoloration. Treatment did not increase either Bleeding or Plaque Index scores at prepared teeth; secondary caries did not appear either. The restorations? survival rate at the 10-year follow-up was 71.4%; six FPDs had fractured and one debonded. Conclusions: Fracture failure rate was 28.6% after 10 years; a high percentage corresponded to connector fractures and occurred during the first 5 years. Lithium disilicate glass-ceramic FPDs present a higher risk of fracture than standard therapies (metal-ceramic) or other more recently developed ceramic materials. The prognosis for survival improves for Class I occlusion and nonparafunctional patients. Int J Prosthodont 2013;26:175?180. doi: 10.11607/ijp.3045