With big data growth in biomedical and healthcare communities, accurate analysis of medical data benefits early disease detection, patient care, and community services. However, the analysis accuracy is reduced when the quality of medical data is incomplete. Moreover, different regions exhibit unique characteristics of certain regional diseases, which may weaken the prediction of disease outbreaks. In this paper, we streamline machine learning algorithms for effective prediction of chronic disease outbreak in disease-frequent communities. We experiment the modified prediction models over real-life hospital data collected from central China in 2013-2015. To overcome the difficulty of incomplete data, we use a latent factor model to reconstruct the missing data. We experiment on a regional chronic disease of cerebral infarction. We propose a new convolutional neural network (CNN)-based multimodal disease risk prediction algorithm using structured and unstructured data from hospital. To the best of our knowledge, none of the existing work focused on both data types in the area of medical big data analytics. Compared with several typical prediction algorithms, the prediction accuracy of our proposed algorithm reaches 94.8% with a convergence speed, which is faster than that of the CNN-based unimodal disease risk prediction algorithm.

Nowadays, skin disease among humans has been a common disease, especially in America millions of people are suffering from various kinds of skin disease. Usually, these diseases have hidden dangers which lead to human not only lack of self-confidence and psychological depression but also a risk of skin cancer. Diagnosis of these kinds of diseases usually required medical experts with high-level instruments due to a lack of visual resolution in skin disease images. Moreover, manual diagnosis of skin disease is often subjective, time-consuming, and required more human effort. Thus, there is a need to develop a computer-aided system that automatically diagnoses the skin disease problem. Moreover, most of the existing works in skin disease used convolutional neural networks (CNN) with classical loss functions, which limit the model to learn discriminative features from skin images. Thus to address the above mention problem we proposed a new framework by fine-tuning layers of ResNet152 and InceptionResNet-V2 models with a triplet loss function. In the proposed framework, first, we learning the embedding from input images into Euclidean space by using deep CNN ResNet152 and InceptionResNet-V2 model. Second, we compute L-2 distance among corresponding images from euclidean space to learn discriminative features of skin disease images by using triplet loss function. Finally, classify the input images using these L-2 distances. Human face skin disease images used in the proposed framework are acquired from the Hospital in Wuhan China. Experiment results and their analysis shows the effectiveness of the proposed framework which achieve better accuracy than many existing works in skin disease tasks.

Developments and new advances in medical technology and the improvement of people’s living standards have helped to make many people healthier. However, there are still large design deficiencies due to the imbalanced distribution of medical resources, especially in developing countries. To address this issue, a video conference-based telemedicine system is deployed to break the limitations of medical resources in terms of time and space. By outsourcing medical resources from big hospitals to rural and remote ones, centralized and high quality medical resources can be shared to achieve a higher salvage rate while improving the utilization of medical resources. Though effective, existing telemedicine systems only treat patients’ physiological diseases, leaving another challenging problem unsolved: How to remotely detect patients’ emotional state to diagnose psychological diseases. In this paper, we propose a novel healthcare system based on a 5G Cognitive System (5G-Csys). The 5G-Csys consists of a resource cognitive engine and a data cognitive engine. Resource cognitive intelligence, based on the learning of network contexts, aims at ultra-low latency and ultra-high reliability for cognitive applications. Data cognitive intelligence, based on the analysis of healthcare big data, is used to handle a patient’s health status physiologically and psychologically. In this paper, the architecture of 5G-Csys is first presented, and then the key technologies and application scenarios are discussed. To verify our proposal, we develop a prototype platform of 5G-Csys, incorporating speech emotion recognition. We present our experimental results to demonstrate the effectiveness of the proposed system. We hope this paper will attract further research in the field of healthcare based on 5G cognitive systems.

As a foundation of large language models, fine-tuning drives rapid progress, broad applicability, and profound impacts on human–AI collaboration, surpassing earlier technological advancements. This paper provides a comprehensive overview of large language model (LLM) fine-tuning by integrating hermeneutic theories of human comprehension, with a focus on the essential cognitive conditions that underpin this process. Drawing on Gadamer’s concepts of Vorverständnis, Distanciation, and the Hermeneutic Circle, the paper explores how LLM fine-tuning evolves from initial learning to deeper comprehension, ultimately advancing toward self-awareness. It examines the core principles, development, and applications of fine-tuning techniques, emphasizing its growing significance across diverse field and industries. The paper introduces a new term, “Tutorial Fine-Tuning (TFT)”, which annotates a process of intensive tuition given by a “tutor” to a small number of “students”, to define the latest round of LLM fine-tuning advancements. By addressing key challenges associated with fine-tuning, including ensuring adaptability, precision, credibility and reliability, this paper explores potential future directions for the co-evolution of humans and AI. By bridging theoretical perspectives with practical implications, this work provides valuable insights into the ongoing development of LLMs, emphasizing their potential to achieve higher levels of cognitive and operational intelligence.

Dynamic complexity in brain functional connectivity has hindered the effective use of signal processing or machine learning methods to diagnose neurological disorders such as epilepsy. This paper proposed a new graph-generative neural network (GGN) model for the dynamic discovery of brain functional connectivity via deep analysis of scalp electroencephalogram (EEG) signals recorded from various regions of a patient’s scalp. Brain functional connectivity graphs are generated for the extraction of spatial–temporal resolution of various onset epilepsy seizure patterns. Our supervised GGN model was substantiated by seizure detection and classification experiments. We train the GGN model using a clinically proven dataset of over 3047 epileptic seizure cases. The GGN model achieved a 91% accuracy in classifying seven types of epileptic seizure attacks, which outperformed the 65%, 74%, and 82% accuracy in using the convolutional neural network (CNN), graph neural networks (GNN), and transformer models, respectively. We present the GGN model architecture and operational steps to assist neuroscientists or brain specialists in using dynamic functional connectivity information to detect neurological disorders. Furthermore, we suggest to merge our spatial–temporal graph generator design in upgrading the conventional CNN and GNN models with dynamic convolutional kernels for accuracy enhancement.