Background and Objectives: This study aimed to examine the function of various inflammation parameters and their interactions in the pathology of Bipolar disorder (BD) and to assess whether they could be biomarkers in the relationship between criminal behavior and BD. Materials and Methods: Overall, 1029 participants, including 343 patients with BD who have committed offenses, 343 nonoffending patients with BD, and 343 healthy controls, were included in this retrospective study. Neutrophil, lymphocyte, monocyte, and platelet counts; high-density lipoprotein (HDL-c) levels; systemic immune-inflammatory index (SII), systemic inflammatory response index (SIRI), neutrophil to high-density lipoprotein ratio (NHR), lymphocyte to high-density lipoprotein ratio (LHR), monocyte to high-density lipoprotein ratio (MHR), platelet to high-density lipoprotein ratio (PHR) were measured. Results: Significant differences were observed between the groups in terms of SII, SIRI, NHR, LHR, MHR, PHR, neutrophil, and monocyte values (p < 0.001). The lymphocyte counts were significantly higher in the patients with BD who committed offenses (p = 0.04). The platelet counts were significantly lower in the patients with BD who committed offenses compared to nonoffending patients with BD (p = 0.015). The HDL-c levels were significantly lower in the patients with BD who have committed offenses than those of nonoffending patients with BD (p < 0.001). Bipolar disorder, not receiving active psychiatric treatment, having a diagnosis of bipolar manic episodes, and having low platelet and HDL values constitute a risk of involvement in crime. Conclusions: The present study emphasizes the role of systemic inflammation in the pathophysiology of patients with BD with and without criminal offenses and the relationship between inflammation and criminal behavior.

Cancer is a devastating disease that has significant psychological and biological impacts. Generally, lung cancer primarily affects men while breast cancer primarily affects women. Thus, this study aimed to investigate the levels of anxiety and depression in patients with these prevalent cancer types, as well as their perceptions of the illness and any potential connections between them. The study included a total of 252 participants, consisting of 110 breast cancer patients, 112 lung cancer patients, and 30 healthy individuals as controls. The Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI) were administered to assess mood, while the Illness Perception Questionnaire (IPQ) was used to evaluate cancer perceptions. Results revealed that both breast cancer and lung cancer patients had significantly higher BDI and BAI scores compared to the control group. Furthermore, the BDI and BAI scores were lower in breast cancer patients compared to lung cancer patients. The IPQ causal representation–immunity score was significantly higher in lung cancer patients than in breast cancer patients (p = 0.01). Positive correlations were found between BDI scores and BAI scores, as well as between BDI scores and certain subscale scores of the IPQ related to illness representation and causal representation. Additionally, a positive correlation was observed between BAI scores and the IPQ illness representation–timeline acute/chronic subscale, while a negative correlation was found between BAI scores and the IPQ causal representation–accident or chance scores. Overall, the study findings demonstrated that breast and lung cancer patients possess negative perceptions of their disease and experience high levels of anxiety and depression. To enhance the quality of life and promote resilience in these patients, it is recommended to incorporate psychological interventions that consider anxiety, depression, and disease perception.

Depression,arterial stiffness,cardiovascular risk,elastic modulus,intimamedia thickness

Aim: In the study, it is aimed to analyze the sociodemographic characteristics of the convicted patients, who were treated in the High-Security Forensic Psychiatry Services (HSFPS) of Elazig Fethi Sekin City Hospital within a period of one year. Material and Methods: 409 convicted psychiatric patients, who applied to Elazig Fethi Sekin City Hospital High-Security Forensic Psychiatry Service were included in this study between March 2020 and March 2021. Personal data pertaining to these patients were obtained from hospital archive records. A general information questionnaire including sociodemographic data prepared by the authors, was used in the study. The sociodemography data form consists of 20 questions in total.Results: The analysis of the collected data revealed that the convicted psychiatric patients were mostly single or divorced, that they lived mostly in the city, that 51.1% of them have not worked at any job, that 40.7% of them had a psychiatric disorder with psychotic features, that 84.4% of them committed a crime for the first time and that these crimes were mostly directed at other individuals.Conclusion: In our study, it was observed that the diagnosis of schizophrenia or other psychotic disorders was more common in the convicted group. The high unemployment rate shows the importance of vocational rehabilitation, and the high number of untreated patients shows that closer follow-up will be beneficial. This study shows that applications to high-security forensic psychiatry services are high and it may be beneficial to increase their number throughout the country.

Natural disasters, such as earthquakes, have significant psychological consequences, particularly for vulnerable populations like postpartum women. This study aimed to determine the relationship between perceived social support and mental health among postpartum women who had experienced an earthquake. In this comparative cross-sectional study, the case group ( n = 62) consisted of women who were in their third trimester at the time of the earthquake and gave birth after the disaster, while the control group ( n = 62) comprised women who were also in their third trimester during the earthquake and had given birth but were not residing in the earthquake-affected region and had no prior experience of an earthquake. The study did not include individuals with intellectual disabilities, illiteracy. Data were collected using the Sociodemographic data form, the Edinburgh Postnatal Depression Scale, the Multidimensional Scale of Perceived Social Support (MSPSS), the Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5), and the Post-Traumatic Growth Inventory (PTGI). The incidence rates of Posttraumatic Stress Disorder (40.3%) and Postpartum depression (43.5%) in postpartum women who experienced the earthquake were significantly higher than those in women who did not (Posttraumatic stress disorder: 6.5%, Postpartum depression: 16.1%) (respectively, p <.001; p  =.001). The mean total MSPSS score of postpartum women who experienced the earthquake (61.7 ± 16.9) was significantly higher than that of those who did not (51.9 ± 13.2) ( p <.001). The mean PTGI total score in postpartum women who experienced the earthquake (69.0 ± 19.2) was significantly higher than in the control group (57.3 ± 20.0) ( p  =.001). In postpartum women who experienced the earthquake, there was a significant positive correlation between PTGI and MSPSS scores, and between PCL-5 and Edinburgh Postnatal Depression Scale scores ( p <.001). Pregnant women who experienced the earthquake had significantly higher posttraumatic stress disorder and postpartum depression scores compared to those who did not. It was concluded that perceived social support may promote posttraumatic growth in women who have experienced a postpartum earthquake.

Aslı Kazgan Kılıçaslan, Burcu Sırlıer Emir, Sevler Yıldız, Gülhan Kılıçaslan, Osman Kurt. Clin Psychopharmacol Neurosci 2023;21:516-25. https://doi.org/10.9758/cpn.22.1009