This paper presents a review on design issues and solutions found in active lower limb prostheses. This review is based on a systematic literature search with a methodical search strategy. The search was carried out across four major technical databases and the retrieved records were screened for their relevance. A total of 21 different active prostheses, including 8 above-knee, 9 below-knee and 4 combined knee-ankle prostheses were identified. While an active prosthesis may help to restore the functional performance of an amputee, the requirements regarding the actuation unit as well as for the control system are high and the development becomes a challenging task. Regarding mechanical design and the actuation unit high force/torque delivery, high efficiency, low size and low weight are conflicting goals. The actuation principle and variable impedance actuators are discussed. The control system is paramount for a “natural functioning” of the prosthesis. The control system has to enable locomotion and should react to the amputee’s intent. For this, multi-level control approaches are reviewed.

Assistive and rehabilitation devices are a promising and challenging field of recent robotics research. Motivated by societal needs such as aging populations, such devices can support motor functionality and subject training. The design, control, sensing and assessment of the devices become more sophisticated due to a human in the loop. This paper gives a human-robot interaction perspective on current issues and opportunities in the field. On the topic of control and machine learning, approaches that support but do not distract subjects are reviewed. Options to provide sensory user-feedback that are currently missing from robotic devices are outlined. Parallels between device acceptance and affective computing are made. Furthermore, requirements for functional assessment protocols that relate to real-world tasks are discussed. In all topic areas, the design of human-oriented frameworks and methods is dominated by challenges related to the close interaction between the human and robotic device. This paper discusses the aforementioned aspects in order to open up new perspectives for future robotic solutions.

This review paper aims to develop a knowledge base and identify promising research pathways toward designing lower limb prostheses for optimal biomechanical and clinical outcomes. It is based on a literature search representing the state-of-the-art in lower limb prosthesis joint design and biomechanical analysis. Current design solutions are organized in terms of fulfilling four key functional roles body — support, propulsion, task flexibility, and loading relief. Biomechanical analyses of these designs reveal that the hypothesized outcomes are not consistently observed. We suggest that these outcomes may be improved by incorporating tools that can predict user performance metrics to optimize the device during the initial design process. We also note that the scope of the solution space of most current designs is limited by focusing on anthropomorphic design approaches that do not account for the person’s altered anatomy post-amputation. The effects of prosthetic joint behavior on whole-body gait biomechanics and user experience are likewise under-explored. Two research paths to support the goal of better predicting user outcomes are proposed: experimental parameterization of designs and model-based simulations. However, while work in these areas has introduced promising new possibilities, connecting both to improve real-world performance remains a challenge.

This article presents a systematic review on wearable robotic devices that use human-in-the-loop optimization (HILO) strategies to improve human–robot interaction. A total of 46 HILO studies were identified and divided into upper and lower limb robotic devices. The main aspects from HILO were identified, reviewed, and classified in four areas: 1) human–machine systems; 2) optimization methods; 3) control strategies; and 4) experimental protocols. A variety of objective functions (physiological, biomechanical, and subjective), optimization strategies, and optimized control parameters configurations used in different control strategies are presented and analyzed. An overview of experimental protocols is provided, including metrics, tasks, and conditions tested. Moreover, the relevance given to training or adaptation periods was explored. We outline an HILO framework that includes current wearable robots, optimization strategies, objective functions, control strategies, and experimental protocols. We conclude by highlighting current research gaps and defining future directions to improve the development of advanced HILO strategies in upper and lower limb wearable robots.