Iasonas F. Triantis

Dr. Iasonas F. Triantis

Engineering, City, University of London, London, City of London, UK
orcid

Research Focus & Metrics

Academic Career Length

25Years (2002-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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6 March 2013 in IEEE Sensors Journal
Verified
Journal Article
Closed access
Panagiotis KassanosPanagiotis Kassanos
Panagiotis Kassanos
ITIasonas F. Triantis
Iasonas F. Triantis
ADAndreas Demosthenous
Andreas Demosthenous
The measurement of electrical impedance is used in a plethora of biomedical applications. The most common technique used is synchronous demodulation, which provides the real and imaginary parts of the impedance. However, in practice, the method requires elaborate calibration and matching between the injection and monitoring stages. This paper presents the integrated realization of an alternative method that is less intricate to implement. The circuit was fabricated in a 0.35-μm CMOS technology, occupies an active area of 0.4 mm 2 , and dissipates about 21 mW of power from ±2.5 V supplies. The chip was used to measure equivalent RC circuits of the electrode-tissue interface over the frequency range of 100 Hz to 100 kHz, showing good correlation with the theoretical results.

21 September 2022 in Sensors
Verified
Journal Article
Open access
PDF file
IGIman Maimunat Gidado
Iman Maimunat Gidado
Meha QassemMeha Qassem
Meha Qassem
ITIasonas F. Triantis
Iasonas F. Triantis
Panicos KyriacouPanicos Kyriacou
Panicos Kyriacou
The presence of water in the skin is crucial for maintaining the properties and functions of the skin, in particular its outermost layer, known as the stratum corneum, which consists of a lipid barrier. External exposures can affect the skin’s hydration levels and in turn, alter its mechanical and physical properties. Monitoring these alterations in the skin’s water content can be applicable in clinical, cosmetic, athletic and personal settings. Many techniques measuring this parameter have been investigated, with electrical-based methods currently being widely used in commercial devices. Furthermore, the exploration of optical techniques to measure hydration is growing due to the outcomes observed through the penetration of light at differing levels. This paper comprehensively reviews such measurement techniques, focusing on recent experimental studies and state-of-the-art devices.

7 April 2014 in IEEE Sensors Journal
Verified
Journal Article
Open access
Panagiotis KassanosPanagiotis Kassanos
Panagiotis Kassanos
LCLoucas Constantinou
Loucas Constantinou
ITIasonas F. Triantis
Iasonas F. Triantis
ADAndreas Demosthenous
Andreas Demosthenous
Bioimpedance spectroscopy is used in a wide range of biomedical applications. This paper presents an integrated analog readout, which employs synchronous detection to perform galvanostatic multi-channel, multi-frequency bioimpedance measurements. The circuit was fabricated in a 0.35-μm CMOS technology and occupies an area of 1.52 mm 2 . The effect of random dc offsets is investigated, along with the use of chopping to minimize them. Impedance measurements of a known RC load and skin (using commercially available electrodes) demonstrate the operation of the system over a frequency range up to 1 MHz. The circuit operates from a ±2.5 V power supply and has a power consumption of 3.4-mW per channel.

24 September 2023 in Annals of Biomedical Engineering
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Journal Article
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Mamun RabbaniMamun Rabbani
Mamun Rabbani
EREnayetur Rahman
Enayetur Rahman
MPMichael B Powner
Michael B Powner
ITIasonas F. Triantis
Iasonas F. Triantis
Electrical stimulation as a mode of external enhancement factor in wound healing has been explored widely. It has proven to have multidimensional effects in wound healing including antibacterial, galvanotaxis, growth factor secretion, proliferation, transdifferentiation, angiogenesis, etc. Despite such vast exploration, this modality has not yet been established as an accepted method for treatment. This article reviews and analyzes the approaches of using electrical stimulation to modulate wound healing and discusses the incoherence in approaches towards reporting the effect of stimulation on the healing process. The analysis starts by discussing various processes adapted in in vitro, in vivo, and clinical practices. Later it is focused on in vitro approaches directed to various stages of wound healing. Based on the analysis, a protocol is put forward for reporting in vitro works in such a way that the outcomes of the experiment are replicable and scalable in other setups. This work proposes a ground of unification for all the in vitro approaches in a more sensible manner, which can be further explored for translating in vitro approaches to complex tissue stimulation to establish electrical stimulation as a controlled clinical method for modulating wound healing.

9 April 2012 in IEEE Transactions on Biomedical Engineering
Verified
Journal Article
Closed access
ZMZongxia Mou
Zongxia Mou
ITIasonas F. Triantis
Iasonas F. Triantis
VWVirginia M. Woods
Virginia M. Woods
CTChristofer Toumazou
Christofer Toumazou
Konstantin NikolicKonstantin Nikolic
Konstantin Nikolic
The electrical behavior of the Xenopus laevis nerve fibers was studied when combined electrical (cuff electrodes) and optical (infrared laser, low power sub-5 mW) stimulations are applied. Assuming that the main effect of the laser irradiation on the nerve tissue is the localized temperature increase, this paper analyzes and gives new insights into the function of the combined thermoelectric stimulation on both excitation and blocking of the nerve action potentials (AP). The calculations involve a finite-element model (COMSOL) to represent the electrical properties of the nerve and cuff. Electric-field distribution along the nerve was computed for the given stimulation current profile and imported into a NEURON model, which was built to simulate the electrical behavior of myelinated nerve fiber under extracellular stimulation. The main result of this study of combined thermoelectric stimulation showed that local temperature increase, for the given electric field, can create a transient block of both the generation and propagation of the APs. Some preliminary experimental data in support of this conclusion are also shown.

19 January 2022 in Sensors
Verified
Journal Article
Open access
PDF file
MSMahsa Sheikh
Mahsa Sheikh
Meha QassemMeha Qassem
Meha Qassem
ITIasonas F. Triantis
Iasonas F. Triantis
Panicos KyriacouPanicos Kyriacou
Panicos Kyriacou
Since the mid-20th century, lithium continues to be prescribed as a first-line mood stabilizer for the management of bipolar disorder (BD). However, lithium has a very narrow therapeutic index, and it is crucial to carefully monitor lithium plasma levels as concentrations greater than 1.2 mmol/L are potentially toxic and can be fatal. The quantification of lithium in clinical laboratories is performed by atomic absorption spectrometry, flame emission photometry, or conventional ion-selective electrodes. All these techniques are cumbersome and require frequent blood tests with consequent discomfort which results in patients evading treatment. Furthermore, the current techniques for lithium monitoring require highly qualified personnel and expensive equipment; hence, it is crucial to develop low-cost and easy-to-use devices for decentralized monitoring of lithium. The current paper seeks to review the pertinent literature rigorously and critically with a focus on different lithium-monitoring techniques which could lead towards the development of automatic and point-of-care analytical devices for lithium determination.