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Dr. Idoia Labayen
Department of Health Sciences, Public University of Navarra, 31006 Pamplona, Spain

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Journal article
Published: 18 April 2021 in Nutrients
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Dietary habits have been linked with health in childhood. However, few studies have examined the association between healthy dietary patterns and physical fitness. Therefore, the aim of this study was to examine the associations of adherence to the Mediterranean dietary pattern (MDP) and breakfast quality with physical fitness in children. Further to this, we examined the role of physical activity in these associations. A total of 175 children (86 girls, 9.7 ± 0.3 years) participated. Adherence to MDP and breakfast quality were assessed by the KIDMED questionnaire and 24 h recall, respectively. Cardiorespiratory fitness, muscular strength, and speed–agility were assessed. Physical activity was evaluated by wrist-worn accelerometers. Greater adherence to the MDP was related with higher cardiorespiratory fitness, lower-limbs muscular strength, and speed–agility (all β ≥ 0.189, all p ≤ 0.02). No significant associations were observed between breakfast quality and physical fitness (all p > 0.05). However, all the significant associations disappeared after adjusting for physical activity (all p > 0.05). Our study sheds light on the relevance of adhering to the MDP over physical fitness in school children. However, there is no association between breakfast quality and physical fitness. Furthermore, physical activity seems to explain, at least partially, these findings.

ACS Style

Cristina Cadenas-Sanchez; María Medrano; Lide Arenaza; Maria Amasene; Maddi Osés; Idoia Labayen. Association between Mediterranean Dietary Pattern and Breakfast Quality with Physical Fitness in School Children: The HIIT Project. Nutrients 2021, 13, 1353 .

AMA Style

Cristina Cadenas-Sanchez, María Medrano, Lide Arenaza, Maria Amasene, Maddi Osés, Idoia Labayen. Association between Mediterranean Dietary Pattern and Breakfast Quality with Physical Fitness in School Children: The HIIT Project. Nutrients. 2021; 13 (4):1353.

Chicago/Turabian Style

Cristina Cadenas-Sanchez; María Medrano; Lide Arenaza; Maria Amasene; Maddi Osés; Idoia Labayen. 2021. "Association between Mediterranean Dietary Pattern and Breakfast Quality with Physical Fitness in School Children: The HIIT Project." Nutrients 13, no. 4: 1353.

Journal article
Published: 16 February 2021 in Journal of Clinical Medicine
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The aim of this study is to evaluate if screen time and parents’ education levels are associated with adherence to a Mediterranean dietary pattern. This cross-sectional study analyzed a representative sample of 3333 children and adolescents (8 to 16 years) included in the Physical Activity, Sedentarism, lifestyles and Obesity in Spanish youth (PASOS) study in Spain (which ran from March 2019 to February 2020). Data on screen time (television, computer, video games, and mobile phone) per day, Mediterranean diet adherence, daily moderate or vigorous physical activity, and parents’ education levels were gathered using questionnaires. A descriptive study of the variables according to sex and parents’ education level was performed. Logistic regression models (adjusted by sex and weight status) were fitted to evaluate the independent association between screen time and Kids’ level of adherence to the Mediterranean diet (KIDMED) index, as well as some of its items. A greater amount of screen time was associated with worse adherence to the Mediterranean diet; a lower consumption of fruit, vegetables, fish, legumes, and nuts; and a greater consumption of fast food, sweets, and candies. A lower parents’ education level was associated with worse adherence to the Mediterranean diet. It is necessary to promote the responsible, limited use of screen time, especially in children with parents with a lower education level.

ACS Style

Julia Wärnberg; Napoleón Pérez-Farinós; Juan Benavente-Marín; Santiago Gómez; Idoia Labayen; Augusto G. Zapico; Narcis Gusi; Susana Aznar; Pedro Alcaraz; Miguel González-Valeiro; Lluís Serra-Majem; Nicolás Terrados; Josep Tur; Marta Segú; Camille Lassale; Clara Homs; Maddi Oses; Marcela González-Gross; Jesús Sánchez-Gómez; Fabio Jiménez-Zazo; Elena Marín-Cascales; Marta Sevilla-Sánchez; Estefanía Herrera-Ramos; Susana Pulgar; María Bibiloni; Olga Sancho-Moron; Helmut Schröder; F. Barón-López. Screen Time and Parents’ Education Level Are Associated with Poor Adherence to the Mediterranean Diet in Spanish Children and Adolescents: The PASOS Study. Journal of Clinical Medicine 2021, 10, 795 .

AMA Style

Julia Wärnberg, Napoleón Pérez-Farinós, Juan Benavente-Marín, Santiago Gómez, Idoia Labayen, Augusto G. Zapico, Narcis Gusi, Susana Aznar, Pedro Alcaraz, Miguel González-Valeiro, Lluís Serra-Majem, Nicolás Terrados, Josep Tur, Marta Segú, Camille Lassale, Clara Homs, Maddi Oses, Marcela González-Gross, Jesús Sánchez-Gómez, Fabio Jiménez-Zazo, Elena Marín-Cascales, Marta Sevilla-Sánchez, Estefanía Herrera-Ramos, Susana Pulgar, María Bibiloni, Olga Sancho-Moron, Helmut Schröder, F. Barón-López. Screen Time and Parents’ Education Level Are Associated with Poor Adherence to the Mediterranean Diet in Spanish Children and Adolescents: The PASOS Study. Journal of Clinical Medicine. 2021; 10 (4):795.

Chicago/Turabian Style

Julia Wärnberg; Napoleón Pérez-Farinós; Juan Benavente-Marín; Santiago Gómez; Idoia Labayen; Augusto G. Zapico; Narcis Gusi; Susana Aznar; Pedro Alcaraz; Miguel González-Valeiro; Lluís Serra-Majem; Nicolás Terrados; Josep Tur; Marta Segú; Camille Lassale; Clara Homs; Maddi Oses; Marcela González-Gross; Jesús Sánchez-Gómez; Fabio Jiménez-Zazo; Elena Marín-Cascales; Marta Sevilla-Sánchez; Estefanía Herrera-Ramos; Susana Pulgar; María Bibiloni; Olga Sancho-Moron; Helmut Schröder; F. Barón-López. 2021. "Screen Time and Parents’ Education Level Are Associated with Poor Adherence to the Mediterranean Diet in Spanish Children and Adolescents: The PASOS Study." Journal of Clinical Medicine 10, no. 4: 795.

Journal article
Published: 30 January 2021 in Nutrients
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Childhood obesity is a worldwide epidemic. Mediterranean diet (MD) is inversely associated with childhood obesity, but the interaction with other environmental factors, such screen time, might influence the health benefits of a high MD adherence in adolescents. The aim of the present study was to assess whether an association between MD and screen time exists in European adolescents. Moreover, we also explored whether sedentary time has a modulatory effect on the association between MD and adiposity. Adherence to the MD (24 h recalls), screen time (questionnaire), pubertal development, body mass index (BMI), fat mass index (FMI) and waist circumference (WC) were evaluated in 2053 adolescents (54.7% females), aged 12.5–17.5 years. In females, MD adherence was associated with lower BMI and FMI only when they were exposed to less than 338 min/day of screen time (81.8% of females); MD adherence was also associated with lower WC only when females were exposed to less than 143 min/day of screen time (31.5% of females). No significant MD-screen time interaction was observed in males. In conclusion, screen-time-based sedentary behaviours had a modulatory effect in the association between MD adherence and adiposity in European female adolescents.

ACS Style

Miguel Seral-Cortes; Sergio Sabroso-Lasa; Alexandro Bailo-Aysa; Marcela Gonzalez-Gross; Dénes Molnár; Laura Censi; Cristina Molina-Hidalgo; Frederic Gottrand; Stefaan Henauw; Yannis Manios; Christina Mavrogianni; Kurt Widhalm; Anthony Kafatos; Jean Dallongeville; Luis Moreno; Luis Esteban; Idoia Labayen; Pilar De Miguel-Etayo; on behalf of the HELENA Study Group. Mediterranean Diet, Screen-Time-Based Sedentary Behavior and Their Interaction Effect on Adiposity in European Adolescents: The HELENA Study. Nutrients 2021, 13, 474 .

AMA Style

Miguel Seral-Cortes, Sergio Sabroso-Lasa, Alexandro Bailo-Aysa, Marcela Gonzalez-Gross, Dénes Molnár, Laura Censi, Cristina Molina-Hidalgo, Frederic Gottrand, Stefaan Henauw, Yannis Manios, Christina Mavrogianni, Kurt Widhalm, Anthony Kafatos, Jean Dallongeville, Luis Moreno, Luis Esteban, Idoia Labayen, Pilar De Miguel-Etayo, on behalf of the HELENA Study Group. Mediterranean Diet, Screen-Time-Based Sedentary Behavior and Their Interaction Effect on Adiposity in European Adolescents: The HELENA Study. Nutrients. 2021; 13 (2):474.

Chicago/Turabian Style

Miguel Seral-Cortes; Sergio Sabroso-Lasa; Alexandro Bailo-Aysa; Marcela Gonzalez-Gross; Dénes Molnár; Laura Censi; Cristina Molina-Hidalgo; Frederic Gottrand; Stefaan Henauw; Yannis Manios; Christina Mavrogianni; Kurt Widhalm; Anthony Kafatos; Jean Dallongeville; Luis Moreno; Luis Esteban; Idoia Labayen; Pilar De Miguel-Etayo; on behalf of the HELENA Study Group. 2021. "Mediterranean Diet, Screen-Time-Based Sedentary Behavior and Their Interaction Effect on Adiposity in European Adolescents: The HELENA Study." Nutrients 13, no. 2: 474.

Journal article
Published: 06 January 2021 in International Journal of Environmental Research and Public Health
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During the COVID-19 pandemic, entire populations were instructed to live in home-confinement to prevent the expansion of the disease. Spain was one of the countries with the strictest conditions, as outdoor physical activity was banned for nearly two months. This study aimed to analyse the changes in physical activity and sedentary behaviours in Spanish university students before and during the confinement by COVID-19 with special focus on gender. We also analysed enjoyment, the tools used and motivation and impediments for doing physical activity. An online questionnaire, which included the International Physical Activity Questionnaire Short Form and certain “ad hoc” questions, was designed. Students were recruited by distributing an invitation through the administrative channels of 16 universities and a total of 13,754 valid surveys were collected. Overall, university students reduced moderate (−29.5%) and vigorous (−18.3%) physical activity during the confinement and increased sedentary time (+52.7%). However, they spent more time on high intensity interval training (HIIT) (+18.2%) and mind-body activities (e.g., yoga) (+80.0%). Adaptation to the confinement, in terms of physical activity, was handled better by women than by men. These results will help design strategies for each gender to promote physical activity and reduce sedentary behaviour during confinement periods.

ACS Style

Ana Rodríguez-Larrad; Asier Mañas; Idoia Labayen; Marcela González-Gross; Ander Espin; Susana Aznar; José Antonio Serrano-Sánchez; Francisco J. Vera-Garcia; Domingo González-Lamuño; Ignacio Ara; Luis Carrasco-Páez; José Castro-Piñero; Mari Carmen Gómez-Cabrera; Sara Márquez; Josep A. Tur; Narcis Gusi; Pedro J. Benito; Diego Moliner-Urdiales; Jonatan R. Ruiz; Francisco B. Ortega; David Jiménez-Pavón; José Antonio Casajús; Jon Irazusta. Impact of COVID-19 Confinement on Physical Activity and Sedentary Behaviour in Spanish University Students: Role of Gender. International Journal of Environmental Research and Public Health 2021, 18, 369 .

AMA Style

Ana Rodríguez-Larrad, Asier Mañas, Idoia Labayen, Marcela González-Gross, Ander Espin, Susana Aznar, José Antonio Serrano-Sánchez, Francisco J. Vera-Garcia, Domingo González-Lamuño, Ignacio Ara, Luis Carrasco-Páez, José Castro-Piñero, Mari Carmen Gómez-Cabrera, Sara Márquez, Josep A. Tur, Narcis Gusi, Pedro J. Benito, Diego Moliner-Urdiales, Jonatan R. Ruiz, Francisco B. Ortega, David Jiménez-Pavón, José Antonio Casajús, Jon Irazusta. Impact of COVID-19 Confinement on Physical Activity and Sedentary Behaviour in Spanish University Students: Role of Gender. International Journal of Environmental Research and Public Health. 2021; 18 (2):369.

Chicago/Turabian Style

Ana Rodríguez-Larrad; Asier Mañas; Idoia Labayen; Marcela González-Gross; Ander Espin; Susana Aznar; José Antonio Serrano-Sánchez; Francisco J. Vera-Garcia; Domingo González-Lamuño; Ignacio Ara; Luis Carrasco-Páez; José Castro-Piñero; Mari Carmen Gómez-Cabrera; Sara Márquez; Josep A. Tur; Narcis Gusi; Pedro J. Benito; Diego Moliner-Urdiales; Jonatan R. Ruiz; Francisco B. Ortega; David Jiménez-Pavón; José Antonio Casajús; Jon Irazusta. 2021. "Impact of COVID-19 Confinement on Physical Activity and Sedentary Behaviour in Spanish University Students: Role of Gender." International Journal of Environmental Research and Public Health 18, no. 2: 369.

Journal article
Published: 16 December 2020 in Nutrients
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Obesity and metabolic syndrome (MetS) are worldwide major health challenges. The Mediterranean diet (MD) is associated with a better cardiometabolic profile, but these beneficial effects may be influenced by genetic variations, modulating the predisposition to obesity or MetS. The aim was to assess whether interaction effects occur between an obesity genetic risk score (obesity-GRS) and the MD on adiposity and MetS in European adolescents. Multiple linear regression models were used to assess the interaction effects of an obesity-GRS and the MD on adiposity and MetS and its components. Interaction effects between the MD on adiposity and MetS were observed in both sex groups (p < 0.05). However, those interaction effects were only expressed in a certain number of adolescents, when a limited number of risk alleles were present. Regarding adiposity, a total of 51.1% males and 98.7% females had lower body mass index (BMI) as a result of higher MD adherence. Concerning MetS, only 9.9% of males with higher MD adherence had lower MetS scores. However, the same effect was observed in 95.2% of females. In conclusion, obesity-related genotypes could modulate the relationship between MD adherence and adiposity and MetS in European adolescents; the interaction effect was higher in females than in males.

ACS Style

Miguel Seral-Cortes; Sergio Sabroso-Lasa; Pilar De Miguel-Etayo; Marcela Gonzalez-Gross; Eva Gesteiro; Cristina Molina-Hidalgo; Stefaan De Henauw; Éva Erhardt; Laura Censi; Yannis Manios; Eva Karaglani; Kurt Widhalm; Anthony Kafatos; Laurent Beghin; Aline Meirhaeghe; Diego Salazar-Tortosa; Jonatan R. Ruiz; Luis A. Moreno; Luis Mariano Esteban; Idoia Labayen. Interaction Effect of the Mediterranean Diet and an Obesity Genetic Risk Score on Adiposity and Metabolic Syndrome in Adolescents: The HELENA Study. Nutrients 2020, 12, 3841 .

AMA Style

Miguel Seral-Cortes, Sergio Sabroso-Lasa, Pilar De Miguel-Etayo, Marcela Gonzalez-Gross, Eva Gesteiro, Cristina Molina-Hidalgo, Stefaan De Henauw, Éva Erhardt, Laura Censi, Yannis Manios, Eva Karaglani, Kurt Widhalm, Anthony Kafatos, Laurent Beghin, Aline Meirhaeghe, Diego Salazar-Tortosa, Jonatan R. Ruiz, Luis A. Moreno, Luis Mariano Esteban, Idoia Labayen. Interaction Effect of the Mediterranean Diet and an Obesity Genetic Risk Score on Adiposity and Metabolic Syndrome in Adolescents: The HELENA Study. Nutrients. 2020; 12 (12):3841.

Chicago/Turabian Style

Miguel Seral-Cortes; Sergio Sabroso-Lasa; Pilar De Miguel-Etayo; Marcela Gonzalez-Gross; Eva Gesteiro; Cristina Molina-Hidalgo; Stefaan De Henauw; Éva Erhardt; Laura Censi; Yannis Manios; Eva Karaglani; Kurt Widhalm; Anthony Kafatos; Laurent Beghin; Aline Meirhaeghe; Diego Salazar-Tortosa; Jonatan R. Ruiz; Luis A. Moreno; Luis Mariano Esteban; Idoia Labayen. 2020. "Interaction Effect of the Mediterranean Diet and an Obesity Genetic Risk Score on Adiposity and Metabolic Syndrome in Adolescents: The HELENA Study." Nutrients 12, no. 12: 3841.

Journal article
Published: 29 November 2020 in Nutrients
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Regular physical activity (PA) is an important part of the treatment of several medical conditions, including overweight and obesity, in which there may be a weakened appetite control. Eating behaviour traits influence weight control and may be different in active and sedentary subjects. This paper reports the relationships between the time spent in sedentary behaviour and physical activity (PA) of different intensity, and eating behaviour traits in young, healthy adults. Additionally, it reports the results of a six-month-long, randomized, controlled trial to examine the effect of an exercise intervention on eating behaviour traits. A total of 139 young (22.06 ± 2.26 years) healthy adults (68.35% women) with a Body Mass Index (BMI) of 24.95 ± 4.57 kg/m2 were enrolled. Baseline assessments of habitual PA were made using wrist-worn triaxial accelerometers; eating behaviour traits were examined via the self-reported questionnaires: Binge Eating, Three-Factor Eating Questionnaire-R18 and Control of Eating Questionnaire. The subjects were then randomly assigned to one of three groups: control (usual lifestyle), moderate-intensity exercise (aerobic and resistance training 3¨C4 days/week at a heart rate equivalent to 60% of the heart rate reserve (HRres) for the aerobic component, and at 50% of the 1 repetition maximum (RM) for the resistance component), or vigorous-intensity exercise (the same training but at 80% HRres for half of the aerobic training, and 70% RM for the resistance training). At baseline, sedentary behaviour was inversely associated with binge eating (r = −0.181, p < 0.05) and with uncontrolled eating (r = −0.286, p = 0.001). Moderate PA (MPA) was inversely associated with craving control (r = −0.188, p < 0.05). Moderate-to-vigorous PA (MVPA) was directly associated with binge eating (r = 0.302, p < 0.001) and uncontrolled eating (r = 0.346, p < 0.001), and inversely associated with craving control (r = −0.170, p < 0.015). Overall, PA was directly associated with binge eating (r = 0.275, p = 0.001), uncontrolled eating (r = 0.321, p < 0.001) and emotional eating (r = 0.204, p < 0.05). Additionally, only emotional eating was modified by the intervention, increasing in the vigorous-intensity exercise group (p < 0.05). In summary, we observed that time spent in sedentary behaviour/PA of different intensity is associated with eating behaviour traits, especially binge eating in young adults. In contrast, the six-month exercise intervention did not lead to appreciable changes in eating behaviour traits.

ACS Style

Wendy D. Martinez-Avila; Guillermo Sanchez-Delgado; Francisco M. Acosta; Lucas Jurado-Fasoli; Pauline Oustric; Idoia Labayen; John E. Blundell; Jonatan R. Ruiz. Eating Behavior, Physical Activity and Exercise Training: A Randomized Controlled Trial in Young Healthy Adults. Nutrients 2020, 12, 3685 .

AMA Style

Wendy D. Martinez-Avila, Guillermo Sanchez-Delgado, Francisco M. Acosta, Lucas Jurado-Fasoli, Pauline Oustric, Idoia Labayen, John E. Blundell, Jonatan R. Ruiz. Eating Behavior, Physical Activity and Exercise Training: A Randomized Controlled Trial in Young Healthy Adults. Nutrients. 2020; 12 (12):3685.

Chicago/Turabian Style

Wendy D. Martinez-Avila; Guillermo Sanchez-Delgado; Francisco M. Acosta; Lucas Jurado-Fasoli; Pauline Oustric; Idoia Labayen; John E. Blundell; Jonatan R. Ruiz. 2020. "Eating Behavior, Physical Activity and Exercise Training: A Randomized Controlled Trial in Young Healthy Adults." Nutrients 12, no. 12: 3685.

Original article
Published: 27 September 2020 in Obesity
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Objective This study aimed to describe the energy expenditure (EE) and macronutrient oxidation response to an individualized nonshivering cold exposure in young healthy adults. Methods Two different groups of 44 (study 1: 22.1 [SD 2.1] years old, 25.6 [SD 5.2] kg/m2, 34% men) and 13 young healthy adults (study 2: 25.6 [SD 3.0] years old, 23.6 [SD 2.4] kg/m2, 54% men) participated in this study. Resting metabolic rate (RMR) and macronutrient oxidation rates were measured by indirect calorimetry under fasting conditions in a warm environment (for 30 minutes) and in mild cold conditions (for 65 minutes, with the individual wearing a water‐perfused cooling vest set at an individualized temperature adjusted to the individual’s shivering threshold). Results In study 1, EE increased in the initial stage of cold exposure and remained stable for the whole cold exposure (P < 0.001). Mean cold‐induced thermogenesis (9.56 ± 7.9 kcal/h) was 13.9% ± 11.6% of the RMR (range: −14.8% to 39.9% of the RMR). Carbohydrate oxidation decreased during the first 30 minutes of the cold exposure and later recovered up to the baseline values (P < 0.01) in parallel to opposite changes in fat oxidation (P < 0.01). Results were replicated in study 2. Conclusions A 1‐hour mild cold exposure individually adjusted to elicit maximum nonshivering thermogenesis induces a very modest increase in EE and a shift of macronutrient oxidation that may underlie a shift in thermogenic tissue activity.

ACS Style

Guillermo Sanchez‐Delgado; Juan M. A. Alcantara; Francisco M. Acosta; Borja Martinez‐Tellez; Francisco J. Amaro‐Gahete; Elisa Merchan‐Ramirez; Marie Löf; Idoia Labayen; Eric Ravussin; Jonatan R. Ruiz. Energy Expenditure and Macronutrient Oxidation in Response to an Individualized Nonshivering Cooling Protocol. Obesity 2020, 28, 2175 -2183.

AMA Style

Guillermo Sanchez‐Delgado, Juan M. A. Alcantara, Francisco M. Acosta, Borja Martinez‐Tellez, Francisco J. Amaro‐Gahete, Elisa Merchan‐Ramirez, Marie Löf, Idoia Labayen, Eric Ravussin, Jonatan R. Ruiz. Energy Expenditure and Macronutrient Oxidation in Response to an Individualized Nonshivering Cooling Protocol. Obesity. 2020; 28 (11):2175-2183.

Chicago/Turabian Style

Guillermo Sanchez‐Delgado; Juan M. A. Alcantara; Francisco M. Acosta; Borja Martinez‐Tellez; Francisco J. Amaro‐Gahete; Elisa Merchan‐Ramirez; Marie Löf; Idoia Labayen; Eric Ravussin; Jonatan R. Ruiz. 2020. "Energy Expenditure and Macronutrient Oxidation in Response to an Individualized Nonshivering Cooling Protocol." Obesity 28, no. 11: 2175-2183.

Journal article
Published: 19 September 2020 in Clinical Nutrition
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Objective To study the association between usual dietary factors (dietary energy density, nutrient intake, food group consumption, and dietary pattern) and brown adipose tissue (BAT) volume/18F-fluorodeoxyglucose (18F-FDG) uptake after personalized cold exposure in young healthy adults. Methods A total of 122 young adults (n=82 women; 22.0±2.1 years old; 24.8±4.8 kg/m2) took part in this cross-sectional study. Dietary factors were measured via a food frequency questionnaire and three non-consecutive 24 h recalls. Dietary energy density (foods and caloric beverages included) and macronutrient intakes were subsequently estimated using EvalFINUT® software, food group consumption was estimated from the food frequency questionnaire, and different dietary patterns and quality indices were determined according to the reference methods. BAT volume, BAT 18F-FDG uptake, and skeletal muscle 18F-FDG uptake were assessed by static 18F-FDG positron-emission tomography and computed tomography (PET-CT) scans after a 2 h personalized exposure to cold. Results A direct association was detected between dietary energy density and BAT Standardized Uptake Value (SUV)mean (β=0.215; R2=0.044; P=0.022), and between ethanol consumption and BAT volume (β=0.215; R2=0.044; P=0.022). The a priori Mediterranean dietary pattern was inversely associated with BAT SUVmean and SUVpeak (β=-0.273; R2=0.075; P=0.003 and β=-0.255; R2=0.066; P=0.005 respectively). In addition, the diet quality index for a Mediterranean diet and a pro-inflammatory dietary pattern (as determined via the dietary inflammatory index) were directly associated with BAT SUVmean and SUVpeak (SUVmean: β=0.238; R2=0.053; P=0.013 and β=0.256; R2=0.052; P=0.012 respectively; SUVpeak: β=0.278; R2=0.073; P=0.003 and β=0.248; R2=0.049; P=0.016 respectively). After controlling for multiplicity and possible confounders (sex, the evaluation wave and BMI), all the detected associations persisted. Conclusion Dietary factors are slightly associated with BAT volume and/or 18F-FDG uptake after a personalized cold exposure in young adults. Our results provide an overall picture of the potential relationships between dietary factors and BAT-related variables in humans.

ACS Style

Lucas Jurado-Fasoli; Elisa Merchan-Ramirez; Borja Martinez-Tellez; Francisco M. Acosta; Guillermo Sanchez-Delgado; Francisco J. Amaro-Gahete; Victoria Muñoz Hernandez; Wendy D. Martinez-Avila; Lourdes Ortiz-Alvarez; Huiwen Xu; María José Arias Téllez; María Dolores Ruiz-López; Jose M. Llamas-Elvira; Ángel Gil; Idoia Labayen; Jonatan R. Ruiz. Association between dietary factors and brown adipose tissue volume/18F-FDG uptake in young adults. Clinical Nutrition 2020, 40, 1997 -2008.

AMA Style

Lucas Jurado-Fasoli, Elisa Merchan-Ramirez, Borja Martinez-Tellez, Francisco M. Acosta, Guillermo Sanchez-Delgado, Francisco J. Amaro-Gahete, Victoria Muñoz Hernandez, Wendy D. Martinez-Avila, Lourdes Ortiz-Alvarez, Huiwen Xu, María José Arias Téllez, María Dolores Ruiz-López, Jose M. Llamas-Elvira, Ángel Gil, Idoia Labayen, Jonatan R. Ruiz. Association between dietary factors and brown adipose tissue volume/18F-FDG uptake in young adults. Clinical Nutrition. 2020; 40 (4):1997-2008.

Chicago/Turabian Style

Lucas Jurado-Fasoli; Elisa Merchan-Ramirez; Borja Martinez-Tellez; Francisco M. Acosta; Guillermo Sanchez-Delgado; Francisco J. Amaro-Gahete; Victoria Muñoz Hernandez; Wendy D. Martinez-Avila; Lourdes Ortiz-Alvarez; Huiwen Xu; María José Arias Téllez; María Dolores Ruiz-López; Jose M. Llamas-Elvira; Ángel Gil; Idoia Labayen; Jonatan R. Ruiz. 2020. "Association between dietary factors and brown adipose tissue volume/18F-FDG uptake in young adults." Clinical Nutrition 40, no. 4: 1997-2008.

Journal article
Published: 16 May 2020 in Nutrients
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Healthy lifestyle education programs are recommended for obesity prevention and treatment. However, there is no previous information on the effects of these programs on the reduction of hepatic fat percentage. The aims were (i) to examine the effectiveness of a 22-week family-based lifestyle education program on dietary habits, and (ii) to explore the associations of changes in dietary intake with percent hepatic fat reduction and adiposity in children with overweight/obesity. A total of 81 children with overweight/obesity (aged 10.6 ± 1.1 years, 53.1% girls) and their parents attended a 22-week family based healthy lifestyle and psychoeducational program accompanied with (intensive group) or without (control) an exercise program. Hepatic fat (magnetic resonance imaging), adiposity (dual energy X-ray absorptiometry) and dietary habits (two non-consecutive 24 h-recalls) were assessed before and after the intervention. Energy (p < 0.01) fat (p < 0.01) and added sugar (p < 0.03) intake were significantly reduced in both groups at the end of the program, while, in addition, carbohydrates intake (p < 0.04) was reduced exclusively in the control group, and simple sugar (p < 0.05) and cholesterol (p < 0.03) intake was reduced in the exercise group. Fruit (p < 0.03) and low-fat/skimmed dairy consumption (p < 0.02), the adherence to the Mediterranean Diet Quality Index for children and teenagers (KIDMED, p < 0.01) and breakfast quality index (p < 0.03) were significantly higher in both control and intervention groups after the intervention. Moreover, participants in the exercise group increased the adherence to the Dietary Approaches to Stop Hypertension (DASH) diet (p < 0.001), whereas the ratio of evening-morning energy intake was significantly lower exclusively in the control group after the program (p < 0.02). Changes in energy intake were significantly associated with changes in fat mass index (FMI) in the exercise group, whereas changes in sugar-sweetened beverages (SSB) consumption was associated with percent hepatic fat reduction (p < 0.05) in the control group. A 22-week family-based healthy lifestyle program seems to be effective on improving diet quality and health in children with overweight/obesity and these should focus on SSB avoidance and physical activity.

ACS Style

Lide Arenaza; María Medrano; Maddi Oses; Maria Amasene; Ignacio Díez; Beatriz Rodríguez-Vigil; Idoia Labayen. The Effect of a Family-Based Lifestyle Education Program on Dietary Habits, Hepatic Fat and Adiposity Markers in 8–12-Year-Old Children with Overweight/Obesity. Nutrients 2020, 12, 1443 .

AMA Style

Lide Arenaza, María Medrano, Maddi Oses, Maria Amasene, Ignacio Díez, Beatriz Rodríguez-Vigil, Idoia Labayen. The Effect of a Family-Based Lifestyle Education Program on Dietary Habits, Hepatic Fat and Adiposity Markers in 8–12-Year-Old Children with Overweight/Obesity. Nutrients. 2020; 12 (5):1443.

Chicago/Turabian Style

Lide Arenaza; María Medrano; Maddi Oses; Maria Amasene; Ignacio Díez; Beatriz Rodríguez-Vigil; Idoia Labayen. 2020. "The Effect of a Family-Based Lifestyle Education Program on Dietary Habits, Hepatic Fat and Adiposity Markers in 8–12-Year-Old Children with Overweight/Obesity." Nutrients 12, no. 5: 1443.

Journal article
Published: 28 April 2020 in JMIR mHealth and uHealth
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Background Best-practice early interventions to increase physical activity (PA) in children with overweight and obesity should be both feasible and evidence based. Walking is a basic human movement pattern that is practical, cost-effective, and does not require complex movement skills. However, there is still a need to investigate how much walking—as a proportion of total PA level—is performed by children who are overweight and obese in order to determine its utility as a public health strategy. Objective This study aimed to (1) investigate the proportion of overall PA indicators that are explained by step-based metrics and (2) study step accumulation patterns relative to achievement of public health recommendations in children who are overweight and obese. Methods A total of 105 overweight and obese children (mean 10.1 years of age [SD 1.1]; 43 girls) wore hip-worn accelerometers for 7 days. PA volumes were derived using the daily average of counts per 15 seconds, categorized using standard cut points for light-moderate-vigorous PA (LMVPA) and moderate-to-vigorous PA (MVPA). Derived step-based metrics included volume (steps/day), time in cadence bands, and peak 1-minute, 30-minute, and 60-minute cadences. Results Steps per day explained 66%, 40%, and 74% of variance for counts per 15 seconds, LMVPA, and MVPA, respectively. The variance explained was increased up to 80%, 92%, and 77% by including specific cadence bands and peak cadences. Children meeting the World Health Organization recommendation of 60 minutes per day of MVPA spent less time at zero cadence and more time in cadence bands representing sporadic movement to brisk walking (ie, 20-119 steps/min) than their less-active peers. Conclusions Step-based metrics, including steps per day and various cadence-based metrics, seem to capture a large proportion of PA for children who are overweight and obese. Given the availability of pedometers, step-based metrics could be useful in discriminating between those children who do or do not achieve MVPA recommendations. Trial Registration ClinicalTrials.gov NCT02295072; https://clinicaltrials.gov/ct2/show/NCT02295072

ACS Style

Jairo H. Migueles; Cristina Cadenas-Sanchez; Elroy J. Aguiar; Pablo Molina-Garcia; Patricio Solis-Urra; Jose Mora-Gonzalez; Eduardo García-Mármol; Eric J. Shiroma; Idoia Labayen; Palma Chillón; Marie Löf; Catrine Tudor-Locke; Francisco B. Ortega; Christopher Moore; Guoqing Hu; Britta Larsen; Mihnea Gaman; Amogh Tathe. Step-Based Metrics and Overall Physical Activity in Children With Overweight or Obesity: Cross-Sectional Study. JMIR mHealth and uHealth 2020, 8, e14841 .

AMA Style

Jairo H. Migueles, Cristina Cadenas-Sanchez, Elroy J. Aguiar, Pablo Molina-Garcia, Patricio Solis-Urra, Jose Mora-Gonzalez, Eduardo García-Mármol, Eric J. Shiroma, Idoia Labayen, Palma Chillón, Marie Löf, Catrine Tudor-Locke, Francisco B. Ortega, Christopher Moore, Guoqing Hu, Britta Larsen, Mihnea Gaman, Amogh Tathe. Step-Based Metrics and Overall Physical Activity in Children With Overweight or Obesity: Cross-Sectional Study. JMIR mHealth and uHealth. 2020; 8 (4):e14841.

Chicago/Turabian Style

Jairo H. Migueles; Cristina Cadenas-Sanchez; Elroy J. Aguiar; Pablo Molina-Garcia; Patricio Solis-Urra; Jose Mora-Gonzalez; Eduardo García-Mármol; Eric J. Shiroma; Idoia Labayen; Palma Chillón; Marie Löf; Catrine Tudor-Locke; Francisco B. Ortega; Christopher Moore; Guoqing Hu; Britta Larsen; Mihnea Gaman; Amogh Tathe. 2020. "Step-Based Metrics and Overall Physical Activity in Children With Overweight or Obesity: Cross-Sectional Study." JMIR mHealth and uHealth 8, no. 4: e14841.

Journal article
Published: 20 April 2020 in Journal of Sports Sciences
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The aim of the present study was to investigate the existence of a relative age effect (RAE) on physical fitness of preschoolers. Anthropometry and physical fitness were assessed in 3147 children (3–5 years old) using the PREFIT battery. Based on the birth year, participants were divided into 3year groups (3-, 4- and 5-years). Within each year group, 4quarter groups were created: quarter 1, preschoolers born from January to March; quarter 2, from April to June; quarter 3, from July to September; quarter 4, from October to December. The MANCOVA analysis revealed a main effect of year group (Wilks’ λ = 0.383; F10,5996 = 369.64; p < 0.001, ηp2 = 0.381) and of quarter (Wilks’ λ = 0.874; F15,8276.6 = 27.67; p < 0.001; ηp2 = 0.044) over the whole battery of tests. To the best of our knowledge, this is the first study to report the existence of RAE at the preschool stage. In general, performance improved as the relative age increased (i.e., those born in quarter 1 performed better than those in the other quarters). Individualization strategies should be addressed within the same academic year not only in elementary or secondary years but also in preschoolers.

ACS Style

Rocío Cupeiro; Miguel A. Rojo-Tirado; Cristina Cadenas-Sanchez; Enrique G. Artero; Ana B. Peinado; Idoia Labayen; Cecilia Dorado; Natalia M. Arias-Palencia; Diego Moliner-Urdiales; Josep Vidal-Conti; Julio Conde-Caveda; Jose Mora-Gonzalez; Germán Vicente-Rodríguez; Pedro J. Benito; on behalf of the PREFIT project group. The relative age effect on physical fitness in preschool children. Journal of Sports Sciences 2020, 38, 1506 -1515.

AMA Style

Rocío Cupeiro, Miguel A. Rojo-Tirado, Cristina Cadenas-Sanchez, Enrique G. Artero, Ana B. Peinado, Idoia Labayen, Cecilia Dorado, Natalia M. Arias-Palencia, Diego Moliner-Urdiales, Josep Vidal-Conti, Julio Conde-Caveda, Jose Mora-Gonzalez, Germán Vicente-Rodríguez, Pedro J. Benito, on behalf of the PREFIT project group. The relative age effect on physical fitness in preschool children. Journal of Sports Sciences. 2020; 38 (13):1506-1515.

Chicago/Turabian Style

Rocío Cupeiro; Miguel A. Rojo-Tirado; Cristina Cadenas-Sanchez; Enrique G. Artero; Ana B. Peinado; Idoia Labayen; Cecilia Dorado; Natalia M. Arias-Palencia; Diego Moliner-Urdiales; Josep Vidal-Conti; Julio Conde-Caveda; Jose Mora-Gonzalez; Germán Vicente-Rodríguez; Pedro J. Benito; on behalf of the PREFIT project group. 2020. "The relative age effect on physical fitness in preschool children." Journal of Sports Sciences 38, no. 13: 1506-1515.

Journal article
Published: 08 April 2020 in Journal of Clinical Medicine
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The aim of this study was to examine whether metabolically healthy overweight/obese children have greater global and regional gray matter volumes than their metabolically unhealthy peers. We further examined the association between gray matter volume and academic achievement, along with the role of cardiorespiratory fitness in these associations. A total of 97 overweight/obese children (10.0 ± 1.2 years) participated. We classified children as metabolically healthy/unhealthy based on metabolic syndrome cut-offs. Global and regional brain volumes were assessed by magnetic resonance imaging. Academic achievement was assessed using the Woodcock-Muñoz standardized test. Cardiorespiratory fitness was assessed by the 20 m shuttle run test. Metabolically healthy overweight/obese (MHO) children had greater regional gray matter volume compared to those who were metabolically unhealthy (MUO) (all p ≤ 0.001). A similar trend was observed for global gray matter volume (p = 0.06). Global gray matter volume was positively related to academic achievement (β = 0.237, p = 0.036). However, all the associations were attenuated or disappeared after adjusting for cardiorespiratory fitness (p > 0.05). The findings of the present study support that metabolically healthy overweight/obese children have greater gray matter volume compared to those that are metabolically unhealthy, which is in turn related to better academic achievement. However, cardiorespiratory fitness seems to explain, at least partially, these findings.

ACS Style

Cristina Cadenas-Sanchez; Irene Esteban-Cornejo; Jairo H. Migueles; Idoia Labayen; Juan Verdejo Román; Jose Mora-Gonzalez; Pontus Henriksson; José Maldonado; José Gómez-Vida; Charles H. Hillman; Kirk I. Erickson; Arthur F. Kramer; Andrés Catena; Francisco B. Ortega. Differences in Brain Volume between Metabolically Healthy and Unhealthy Overweight and Obese Children: The Role of Fitness. Journal of Clinical Medicine 2020, 9, 1059 .

AMA Style

Cristina Cadenas-Sanchez, Irene Esteban-Cornejo, Jairo H. Migueles, Idoia Labayen, Juan Verdejo Román, Jose Mora-Gonzalez, Pontus Henriksson, José Maldonado, José Gómez-Vida, Charles H. Hillman, Kirk I. Erickson, Arthur F. Kramer, Andrés Catena, Francisco B. Ortega. Differences in Brain Volume between Metabolically Healthy and Unhealthy Overweight and Obese Children: The Role of Fitness. Journal of Clinical Medicine. 2020; 9 (4):1059.

Chicago/Turabian Style

Cristina Cadenas-Sanchez; Irene Esteban-Cornejo; Jairo H. Migueles; Idoia Labayen; Juan Verdejo Román; Jose Mora-Gonzalez; Pontus Henriksson; José Maldonado; José Gómez-Vida; Charles H. Hillman; Kirk I. Erickson; Arthur F. Kramer; Andrés Catena; Francisco B. Ortega. 2020. "Differences in Brain Volume between Metabolically Healthy and Unhealthy Overweight and Obese Children: The Role of Fitness." Journal of Clinical Medicine 9, no. 4: 1059.

Journal article
Published: 20 January 2020 in International Journal of Environmental Research and Public Health
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Multicomponent physical exercise is effective in curbing the effect of hospitalization in older adults. However, it is not well established which characteristics of the exercise interventions would optimize intervention sustainability and efficacy. This study compared the effects of two group-based multicomponent exercise interventions of different lengths in older adults after hospitalization. Fifty-five participants were randomly assigned to a short-term group-based branch (SGB, n = 27) or to a long-term group-based branch (LGB, n = 28). The SGB participated in a six-week multicomponent group-based exercise-training program followed by 18 weeks of home-based exercise. The LGB completed 12 weeks of each phase. Physical function, physical activity, quality of life, anthropometrics, and nutritional status were assessed at baseline, after 12 weeks, and after 24 weeks of intervention. Both groups improved physical function and nutritional status and increased physical activity after 12 weeks of intervention (paired student’s t-test, p < 0.01), and maintained the positive effects during the following 12 weeks. No group-by-time interaction was observed in any of the studied variables using mixed-model ANOVA. Based on these findings, we determined that 6 weeks of a group-based exercise intervention caused similar functional and nutritional benefits to a longer group-based intervention of 12 weeks when both are continued at home until 24 weeks.

ACS Style

Iñaki Echeverria; Maria Amasene; Miriam Urquiza; Idoia Labayen; Pilar Anaut; Ana Rodriguez-Larrad; Jon Irazusta; Ariadna Besga. Multicomponent Physical Exercise in Older Adults after Hospitalization: A Randomized Controlled Trial Comparing Short- vs. Long-Term Group-Based Interventions. International Journal of Environmental Research and Public Health 2020, 17, 666 .

AMA Style

Iñaki Echeverria, Maria Amasene, Miriam Urquiza, Idoia Labayen, Pilar Anaut, Ana Rodriguez-Larrad, Jon Irazusta, Ariadna Besga. Multicomponent Physical Exercise in Older Adults after Hospitalization: A Randomized Controlled Trial Comparing Short- vs. Long-Term Group-Based Interventions. International Journal of Environmental Research and Public Health. 2020; 17 (2):666.

Chicago/Turabian Style

Iñaki Echeverria; Maria Amasene; Miriam Urquiza; Idoia Labayen; Pilar Anaut; Ana Rodriguez-Larrad; Jon Irazusta; Ariadna Besga. 2020. "Multicomponent Physical Exercise in Older Adults after Hospitalization: A Randomized Controlled Trial Comparing Short- vs. Long-Term Group-Based Interventions." International Journal of Environmental Research and Public Health 17, no. 2: 666.

Journal article
Published: 11 December 2019 in The American Journal of Clinical Nutrition
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Background Several studies have explored the role of human brown adipose tissue (BAT) in energy expenditure. However, the link between BAT and appetite regulation needs to be more rigorously examined. Objectives We aimed to investigate the associations of BAT volume and 18F-fluordeoxyglucose (18F-FDG) uptake after a personalized cold exposure with energy intake and appetite-related sensations in young healthy humans. Methods A total of 102 young adults (65 women; age: 22.08 ± 2.17 y; BMI: 25.05 ± 4.93 kg/m 2) took part in this cross-sectional study. BAT volume, BAT 18F-FDG uptake, and skeletal muscle 18F-FDG uptake were assessed by means of static 18F-FDG positron-emission tomography and computed tomography scans after a 2-h personalized exposure to cold. Energy intake was estimated via an objectively measured ad libitum meal and three nonconsecutive 24-h dietary recalls. Appetite-related sensations (i.e., hunger and fullness) were recorded by visual analog scales before and after a standardized breakfast (energy content = 50% of basal metabolic rate) and the ad libitum meal. Body composition was assessed by a whole-body DXA scan. Results BAT volume and 18F-FDG uptake were not associated with quantified ad libitum energy intake (all P > 0.088), nor with habitual energy intake estimated from the 24-h dietary recalls (all P > 0.683). Lean mass was positively associated with both the energy intake from the ad libitum meal (β: 17.612, R2 = 0.213; P < 0.001) and the habitual energy intake (β: 16.052, R2 = 0.123; P = 0.001). Neither the interaction BAT volume × time elapsed after meal consumption nor that of BAT 18F-FDG uptake × time elapsed after meal consumption had any significant influence on appetite-related sensations after breakfast or after meal consumption (all P > 0.3). Conclusions Neither BAT volume, nor BAT 18F-FDG uptake after cold stimulation, are related to appetite regulation in young adults. These results suggest BAT plays no important role in the regulation of energy intake in humans. This trial was registered at clinicaltrials.gov as NCT02365129.

ACS Style

Guillermo Sanchez-Delgado; Francisco M Acosta; Borja Martinez-Tellez; Graham Finlayson; Catherine Gibbons; Idoia Labayen; Jose Manuel Llamas-Elvira; Angel Gil; John E Blundell; Jonatan R Ruiz. Brown adipose tissue volume and 18F-fluorodeoxyglucose uptake are not associated with energy intake in young human adults. The American Journal of Clinical Nutrition 2019, 111, 329 -339.

AMA Style

Guillermo Sanchez-Delgado, Francisco M Acosta, Borja Martinez-Tellez, Graham Finlayson, Catherine Gibbons, Idoia Labayen, Jose Manuel Llamas-Elvira, Angel Gil, John E Blundell, Jonatan R Ruiz. Brown adipose tissue volume and 18F-fluorodeoxyglucose uptake are not associated with energy intake in young human adults. The American Journal of Clinical Nutrition. 2019; 111 (2):329-339.

Chicago/Turabian Style

Guillermo Sanchez-Delgado; Francisco M Acosta; Borja Martinez-Tellez; Graham Finlayson; Catherine Gibbons; Idoia Labayen; Jose Manuel Llamas-Elvira; Angel Gil; John E Blundell; Jonatan R Ruiz. 2019. "Brown adipose tissue volume and 18F-fluorodeoxyglucose uptake are not associated with energy intake in young human adults." The American Journal of Clinical Nutrition 111, no. 2: 329-339.

Review
Published: 27 November 2019 in Nutrients
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Early detection of obesity and its associated comorbidities in children needs priority for the development of effective therapeutic intervention. Circulating miRNAs (microRNAs) have been proposed as biomarkers for obesity and its comorbidities; therefore, we conducted a systematic review to summarize results of studies that have quantified the profile of miRNAs in children and adolescents with obesity and/or associated disorders. Nine studies aiming to examine differences in miRNA expression levels between children with normal weight and obesity or between obese children with or without cardiometabolic diseases were included in this review. We identified four miRNAs overexpressed in obesity (miR-222, miR-142–3, miR-140-5p, and miR-143) and two miRNAs (miR-122 and miR-34a) overexpressed in children with obesity and nonalcoholic fatty liver disease (NAFLD) and/or insulin resistance. In conclusion, circulating miRNAs are promising diagnostic biomarkers of obesity-associated diseases such as NAFLD and type 2 diabetes already in childhood. However, more studies in children, using massive search technology and with larger sample sizes, are required to draw any firm conclusions.

ACS Style

Maddi Oses; Javier Margareto Sanchez; Maria P. Portillo; Concepción María Aguilera; Idoia Labayen. Circulating miRNAs as Biomarkers of Obesity and Obesity-Associated Comorbidities in Children and Adolescents: A Systematic Review. Nutrients 2019, 11, 2890 .

AMA Style

Maddi Oses, Javier Margareto Sanchez, Maria P. Portillo, Concepción María Aguilera, Idoia Labayen. Circulating miRNAs as Biomarkers of Obesity and Obesity-Associated Comorbidities in Children and Adolescents: A Systematic Review. Nutrients. 2019; 11 (12):2890.

Chicago/Turabian Style

Maddi Oses; Javier Margareto Sanchez; Maria P. Portillo; Concepción María Aguilera; Idoia Labayen. 2019. "Circulating miRNAs as Biomarkers of Obesity and Obesity-Associated Comorbidities in Children and Adolescents: A Systematic Review." Nutrients 11, no. 12: 2890.

Journal article
Published: 09 November 2019 in European Heart Journal
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Aims Cardiorespiratory fitness, muscular strength, and obesity in adulthood are risk factors for cardiovascular disease (CVD). However, little is known regarding the associations of these risk factors, already in adolescence, with later disability due to chronic CVD. Hence, we investigated associations of cardiorespiratory fitness, muscular strength, and body mass index (BMI) in adolescence with later chronic disability due to specific causes of CVD disability (i.e. cerebrovascular disease, ischaemic heart disease and heart failure). Methods and results This population-based cohort study included 1 078 685 male adolescents (16–19 years) from the Swedish military conscription register from 1972 to 1994. Cardiorespiratory fitness (bicycle ergometer test), muscular strength (knee extension strength), and BMI were measured during the conscription examination. Information about disability pension due to CVD was retrieved from the Social Insurance Agency during a mean follow-up of 28.4 years. Cardiorespiratory fitness was strongly and inversely associated with later risk of chronic CVD disability for all investigated causes. The association was particularly strong for ischaemic heart diseases (hazard ratio 0.11, 95% confidence interval 0.05–0.29 for highest vs. lowest fitness-quintiles). Furthermore, overweight/obesity were associated with CVD disability for all investigated causes. Conversely, associations of muscular strength with CVD disability were generally weak. Conclusions This study provides evidence for associations between low levels of cardiorespiratory fitness and obesity with later risk of chronic disability due to CVD. Preventive actions may begin at young ages and include promotion of cardiorespiratory fitness and healthy body weight.

ACS Style

Hanna Henriksson; Pontus Henriksson; Per Tynelius; Mattias Ekstedt; Daniel Berglind; Idoia Labayen; Jonatan R Ruiz; Carl J Lavie; Francisco B Ortega. Cardiorespiratory fitness, muscular strength, and obesity in adolescence and later chronic disability due to cardiovascular disease: a cohort study of 1 million men. European Heart Journal 2019, 41, 1503 -1510.

AMA Style

Hanna Henriksson, Pontus Henriksson, Per Tynelius, Mattias Ekstedt, Daniel Berglind, Idoia Labayen, Jonatan R Ruiz, Carl J Lavie, Francisco B Ortega. Cardiorespiratory fitness, muscular strength, and obesity in adolescence and later chronic disability due to cardiovascular disease: a cohort study of 1 million men. European Heart Journal. 2019; 41 (15):1503-1510.

Chicago/Turabian Style

Hanna Henriksson; Pontus Henriksson; Per Tynelius; Mattias Ekstedt; Daniel Berglind; Idoia Labayen; Jonatan R Ruiz; Carl J Lavie; Francisco B Ortega. 2019. "Cardiorespiratory fitness, muscular strength, and obesity in adolescence and later chronic disability due to cardiovascular disease: a cohort study of 1 million men." European Heart Journal 41, no. 15: 1503-1510.

Randomized controlled trial
Published: 01 October 2019 in Nutrients
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Age-related strength and muscle mass loss is further increased after acute periods of inactivity. To avoid this, resistance training has been proposed as an effective countermeasure, but the additional effect of a protein supplement is not so clear. The aim of this study was to examine the effect of a whey protein supplement enriched with leucine after resistance training on muscle mass and strength gains in a post-hospitalized elderly population. A total of 28 participants were included and allocated to either protein supplementation or placebo supplementation following resistance training for 12 weeks (2 days/week). Physical function (lower and upper body strength, aerobic capacity and the Short Physical Performance Battery (SPPB) test), mini nutritional assessment (MNA) and body composition (Dual X-ray Absorptiometry) were assessed at baseline and after 12 weeks of resistance training. Both groups showed improvements in physical function after the intervention (p < 0.01), but there were no further effects for the protein group (p > 0.05). Muscle mass did not improve after resistance training in either group (p > 0.05). In conclusion, 12 weeks of resistance training are enough to improve physical function in a post-hospitalized elderly population with no further benefits for the protein-supplemented group.

ACS Style

Maria Amasene; Ariadna Besga; Iñaki Echeverria; Miriam Urquiza; Jonatan R. Ruiz; Ana Rodriguez-Larrad; Mikel Aldamiz; Pilar Anaut; Jon Irazusta; Idoia Labayen. Effects of Leucine-Enriched Whey Protein Supplementation on Physical Function in Post-Hospitalized Older Adults Participating in 12-Weeks of Resistance Training Program: A Randomized Controlled Trial. Nutrients 2019, 11, 2337 .

AMA Style

Maria Amasene, Ariadna Besga, Iñaki Echeverria, Miriam Urquiza, Jonatan R. Ruiz, Ana Rodriguez-Larrad, Mikel Aldamiz, Pilar Anaut, Jon Irazusta, Idoia Labayen. Effects of Leucine-Enriched Whey Protein Supplementation on Physical Function in Post-Hospitalized Older Adults Participating in 12-Weeks of Resistance Training Program: A Randomized Controlled Trial. Nutrients. 2019; 11 (10):2337.

Chicago/Turabian Style

Maria Amasene; Ariadna Besga; Iñaki Echeverria; Miriam Urquiza; Jonatan R. Ruiz; Ana Rodriguez-Larrad; Mikel Aldamiz; Pilar Anaut; Jon Irazusta; Idoia Labayen. 2019. "Effects of Leucine-Enriched Whey Protein Supplementation on Physical Function in Post-Hospitalized Older Adults Participating in 12-Weeks of Resistance Training Program: A Randomized Controlled Trial." Nutrients 11, no. 10: 2337.

Multicenter study
Published: 01 August 2019 in Journal of Science and Medicine in Sport
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To determine whether handgrip strength (HG) and/or standing long jump (SLJ) are capable of detecting risk of metabolic syndrome (MetS) in European adolescents, and to identify age- and sex-specific cut points for these tests. Cross-sectional study. Participants included 969 (aged 12.5-17.5 years old) adolescents from 9 European countries (n = 520 girls). Absolute and relative HG and SLJ tests were used to assess upper and lower muscle strength, respectively. MetS status was determined using the age- and sex-specific cut points proposed by Jolliffe and Janssen´s, Additionally, we computed a continuous cardiometabolic risk index with the average z-score of four cardiometabolic risk factors: Wait circumference, mean arterial pressure, triglycerides/high-density lipoprotein cholesterol, and fasting insulin. The prevalence of MetS was 3.1% in European adolescents. Relative HG and absolute SLJ were the best tests for detecting the presence of MetS (Area under the receiver operating characteristic (AUC) = 0.799, 95%CI:0.773-0.824; and AUC = 0.695 95%CI:0.665-0.724), respectively) and elevated cardiometabolic risk index (AUC = 0.873, 95%CI:0.838-0.902; and AUC = 0.728 95%CI:0.698-0.756), respectively) and, regardless of cardiorespiratory fitness. We provide age- and sex-specific cut points of upper and lower muscle strength for European adolescents to identify the presence of MetS and elevated cardiometabolic risk index. The proposed health-related cut points could be used as a starting point to define health-related levels of upper and lower muscle strength in adolescents. Likewise, the diagnostic statistics provided herein can be used to offer feedback to adolescents, parents, and education and health professionals about what it means to meet or fail test standards.

ACS Style

José Castro-Piñero; Kelly R. Laurson; Enrique G. Artero; Francisco B Ortega; Idoia Labayen; Azahara I. Ruperez; Mahmoud Zaqout; Yannis Manios; Jeremy Vanhelst; Ascension Marcos; Angela Polito; Marcela Gonzalez-Gross; Kurt Widhalm; Luis A Moreno; Angel Gutierrez; Jonatan R Ruiz. Muscle strength field-based tests to identify European adolescents at risk of metabolic syndrome: The HELENA study. Journal of Science and Medicine in Sport 2019, 22, 929 -934.

AMA Style

José Castro-Piñero, Kelly R. Laurson, Enrique G. Artero, Francisco B Ortega, Idoia Labayen, Azahara I. Ruperez, Mahmoud Zaqout, Yannis Manios, Jeremy Vanhelst, Ascension Marcos, Angela Polito, Marcela Gonzalez-Gross, Kurt Widhalm, Luis A Moreno, Angel Gutierrez, Jonatan R Ruiz. Muscle strength field-based tests to identify European adolescents at risk of metabolic syndrome: The HELENA study. Journal of Science and Medicine in Sport. 2019; 22 (8):929-934.

Chicago/Turabian Style

José Castro-Piñero; Kelly R. Laurson; Enrique G. Artero; Francisco B Ortega; Idoia Labayen; Azahara I. Ruperez; Mahmoud Zaqout; Yannis Manios; Jeremy Vanhelst; Ascension Marcos; Angela Polito; Marcela Gonzalez-Gross; Kurt Widhalm; Luis A Moreno; Angel Gutierrez; Jonatan R Ruiz. 2019. "Muscle strength field-based tests to identify European adolescents at risk of metabolic syndrome: The HELENA study." Journal of Science and Medicine in Sport 22, no. 8: 929-934.

Comment
Published: 21 June 2019 in Diabetes Care
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OBJECTIVE Pediatric hepatic steatosis is highly prevalent and closely related to type 2 diabetes. To determine whether the addition of supervised exercise to a family-based lifestyle and psycho-educational intervention results in greater reduction of percentage of hepatic fat (HF), adiposity, and cardiometabolic risk factors in children with overweight/obesity. RESEARCH DESIGN AND METHODS The study subjects of this nonrandomized, two-arm, parallel design clinical trial were 116 overweight/obese children (10.6 ± 1.1 years of age, 53.4% girls) living in Vitoria-Gasteiz (Spain). For 22 weeks, they followed either a lifestyle- and psycho-education program (control intervention [CInt], N = 57), consisting of two family-based education sessions/month, or the same plus supervised exercise (intensive intervention [II], N = 59) focused mainly on high-intensity aerobic workouts (3 sessions/week, 90 min/session). The primary outcome was the change in percentage of HF (as measured by MRI) between baseline and the end of the intervention period. Secondary outcomes included changes in BMI, fat mass index (FMI), abdominal fat (measured by DEXA), blood pressure, triglycerides, HDL, LDL, γ-glutamyl-transferase, glucose, and insulin concentrations. RESULTS A total of 102 children completed the trial (N = 53 and N = 49 in the CInt and II groups, respectively). Percentage of HF decreased only in the II group (−1.20 ± 0.31% vs. 0.04 ± 0.30%, II and CInt groups, respectively), regardless of baseline value and any change in adiposity (P < 0.01). BMI, FMI, abdominal fat (P ≤ 0.001), and insulin (P < 0.05) were reduced in both groups. CONCLUSIONS Multicomponent intervention programs that include exercise training may help to reduce adiposity, insulin resistance, and hepatic steatosis in overweight/obese children.

ACS Style

Idoia Labayen; María Medrano; Lide Arenaza; Edurne Maiz; Maddi Oses; Vicente Martínez-Vizcaíno; Jonatan R. Ruiz; Francisco B. Ortega. Effects of Exercise in Addition to a Family-Based Lifestyle Intervention Program on Hepatic Fat in Children With Overweight. Diabetes Care 2019, 43, 306 -313.

AMA Style

Idoia Labayen, María Medrano, Lide Arenaza, Edurne Maiz, Maddi Oses, Vicente Martínez-Vizcaíno, Jonatan R. Ruiz, Francisco B. Ortega. Effects of Exercise in Addition to a Family-Based Lifestyle Intervention Program on Hepatic Fat in Children With Overweight. Diabetes Care. 2019; 43 (2):306-313.

Chicago/Turabian Style

Idoia Labayen; María Medrano; Lide Arenaza; Edurne Maiz; Maddi Oses; Vicente Martínez-Vizcaíno; Jonatan R. Ruiz; Francisco B. Ortega. 2019. "Effects of Exercise in Addition to a Family-Based Lifestyle Intervention Program on Hepatic Fat in Children With Overweight." Diabetes Care 43, no. 2: 306-313.

Journal article
Published: 01 June 2019 in Clinical Nutrition
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A standardized and individualized liquid meal test increases the skin temperature in young adults, being the thermic effect higher in women than in men.

ACS Style

Borja Martinez-Tellez; Lourdes Ortiz-Alvarez; Guillermo Sanchez-Delgado; Huiwen Xu; Francisco M. Acosta; Elisa Merchan-Ramirez; Victoria Muñoz-Hernandez; Wendy D. Martinez-Avila; Miguel A. Contreras-Gomez; Angel Gil; Idoia Labayen; Jonatan R. Ruiz. Skin temperature response to a liquid meal intake is different in men than in women. Clinical Nutrition 2019, 38, 1339 -1347.

AMA Style

Borja Martinez-Tellez, Lourdes Ortiz-Alvarez, Guillermo Sanchez-Delgado, Huiwen Xu, Francisco M. Acosta, Elisa Merchan-Ramirez, Victoria Muñoz-Hernandez, Wendy D. Martinez-Avila, Miguel A. Contreras-Gomez, Angel Gil, Idoia Labayen, Jonatan R. Ruiz. Skin temperature response to a liquid meal intake is different in men than in women. Clinical Nutrition. 2019; 38 (3):1339-1347.

Chicago/Turabian Style

Borja Martinez-Tellez; Lourdes Ortiz-Alvarez; Guillermo Sanchez-Delgado; Huiwen Xu; Francisco M. Acosta; Elisa Merchan-Ramirez; Victoria Muñoz-Hernandez; Wendy D. Martinez-Avila; Miguel A. Contreras-Gomez; Angel Gil; Idoia Labayen; Jonatan R. Ruiz. 2019. "Skin temperature response to a liquid meal intake is different in men than in women." Clinical Nutrition 38, no. 3: 1339-1347.