Stella Agradi

Dr. Stella Agradi


Research Focus & Metrics

Academic Career Length

3Years (2024-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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16 January 2025 in Foods
Verified
Journal Article
Open access
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Nour Elhouda FehriNour Elhouda Fehri
Nour Elhouda Fehri
MCMichela Contò
Michela Contò
Marta CastricaMarta Castrica
Marta Castrica
AQAlda Quattrone
Alda Quattrone
GRGianluca Renzi
Gianluca Renzi
Sebastiana FailaSebastiana Faila
Sebastiana Faila
This study investigated the effects of dietary supplementation with extruded linseed (ELS) and Padina pavonica algae extract (PP) on rabbit carcass and meat quality. Ninety-six rabbit carcasses from two production cycles were analyzed. In the first cycle (C1), rabbits were fed a control diet (1CNT), the same diet supplemented with 5% ELS (1ELS5%), and supplemented with 3.5% ELS and 0.2% PP (1LPP3.5%). In the second cycle (C2), the diets varied in composition and supplementation levels: a different control diet (2CNT), the same diet with 5% ELS (2ELS5%), and with 5% ELS and 0.2% PP (2LPP5%). Meat analyses were performed on Longissimus thoracis et lumborum (LTL) muscle for physical properties and on thigh meat (THM) for proximate composition, vitamin E, coenzyme-Q10, cholesterol, fatty acid profile, and mineral content. No significant differences in LTL physical quality were observed in C1, although LTL was brighter in C2 (p < 0.001). THM in C2 had higher fat content (p < 0.001). Dietary supplementation with ELS and PP extract significantly increased polyunsaturated fatty acids (n-3 PUFAs) and improved the n-6/n-3 ratio (p < 0.001) in rabbit meat, demonstrating their positive impact on meat quality.

1 October 2024 in Veterinary Sciences
Verified
Journal Article
Open access
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AQAlda Quattrone
Alda Quattrone
RBRafik Belabbas
Rafik Belabbas
Nour Elhouda FehriNour Elhouda Fehri
Nour Elhouda Fehri
Stella AgradiStella Agradi
Stella Agradi
SMSilvia Michela Mazzola
Silvia Michela Mazzola
Laura MenchettiLaura Menchetti
Laura Menchetti
This study examined the effects of extruded linseed and algae Padina pavonica extract on the reproductive performance, milk production, and gastrointestinal health of female rabbits. Thirty-six nulliparous New Zealand White female rabbits were randomly assigned to three groups (n = 12) with different diets. The control group (CNT) received a standard diet, while the other two groups received modified isoenergetic diets in which part of the CNT diet ingredients were replaced with 5% extruded linseed (L5%) and 5% extruded linseed plus 0.2% Padina pavonica algae extract (L5%PP). The rabbits were monitored from artificial insemination until the weaning of the rabbit kits, evaluating different reproductive parameters. Our results indicate that extruded linseed and alga Padina pavonica extract did not affect the feed intake or body weight of female rabbits. Additionally, no clinically significant histological changes were observed at the gastrointestinal level. The reproductive parameters, including litter size, litter weight, and milk yield, showed no significant differences among groups. Notably, perinatal and pre-weaning mortalities were reduced in litters born to females receiving omega-3 integrated diets (p < 0.05). While these findings are promising, further studies are needed to confirm these results and explore the specific mechanisms by which omega-3 affects reproductive function and litter health.

26 January 2025 in Foods
Verified
Journal Article
Open access
PDF file
Marta CastricaMarta Castrica
Marta Castrica
MCMichela Contò
Michela Contò
Nour Elhouda FehriNour Elhouda Fehri
Nour Elhouda Fehri
Giulio CuroneGiulio Curone
Giulio Curone
Claudia Maria BalzarettiClaudia Maria Balzaretti
Claudia Maria Balzaretti
Sebastiana FailaSebastiana Faila
Sebastiana Faila
This study evaluated the efficacy of an active absorbent pad (aPAD) in reducing microbial growth and enhancing the shelf life of rabbit meat stored in modified atmosphere packaging (MAP). Thigh muscles from 60 rabbits were used, divided into three dietary groups: a control group (CNT), a group supplemented with 5% extruded flaxseed (ELS5%), and a group with 3.5% extruded flaxseed and 0.2% Padina pavonica algae (LPP3.5%). Samples were packaged in MAP (70% O2, 30% CO2) with either a conventional pad (nPAD) or aPAD and analyzed at 1, 4, 7, 14, 21 days. Microbiological analysis revealed a significantly lower total viable count at 21 days in the ELS5%aPAD group. For coagulase-positive staphylococci, the CNTaPAD group showed lower microbial counts at both day 4 and day 21 (p < 0.05). Enterobacteriaceae reductions were observed at 24 h post packaging in both the CNTaPAD and LPP3.5%aPAD groups and at day 14 in ELS5%aPAD. Lipid oxidation (TBARS) was also lower in aPAD samples, particularly in LPP3.5%, which remained below 1.5 mg MDA/kg compared to >2.5 mg MDA/kg in nPAD (p < 0.05). Sensory attributes such as texture and color were better preserved with aPAD. These findings underscore the effectiveness of aPAD in MAP to control microbial growth, limit oxidation, and extend the shelf life of omega-3-enriched rabbit meat, providing a promising solution for functional meat product preservation.

19 September 2024 in Foods
Verified
Journal Article
Open access
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Mohamed AROUAMohamed AROUA
Mohamed AROUA
Nour Elhouda FehriNour Elhouda Fehri
Nour Elhouda Fehri
SSSAMIA BEN SAID
SAMIA BEN SAID
AQAlda Quattrone
Alda Quattrone
Stella AgradiStella Agradi
Stella Agradi
Marta CastricaMarta Castrica
Marta Castrica
The aim of this study was to evaluate the use of horse and donkey meat in the production of kaddid—a traditional dish typically not made with these meats—from a physical and chemical perspective. The results showed that both meats exhibit similar water retention during cooking, contributing to comparable tenderness and juiciness, with no significant differences in pH values, indicating similar quality (p > 0.05). However, their amino acid profiles differ: horse meat contains lower levels of glutamate (p < 0.05), methionine (p < 0.01), isoleucine (p < 0.05), and leucine (p < 0.05), but higher levels of proline (p < 0.05), histidine (p < 0.01), and lysine (p < 0.001) compared to donkey meat. Both meats provide essential amino acids. Horse meat is richer in saturated and monounsaturated fatty acids (32.44% and 39.58%, respectively), while donkey meat has a higher content of polyunsaturated fatty acids (31.51%), with a more favorable PUFA/SFA ratio, suggesting better cardiovascular health benefits. In terms of dried meat, donkey kaddid has a higher protein (17.45 g/100 g) and lower fat content (2.1 g/100 g) compared to horse kaddid (16.7 g/100 g, and 3.5 g/100 g, respectively) (p < 0.05). These findings inform consumer choices and production practices, promoting the use of horse and donkey meat for kaddid production.

16 May 2025 in Diversity
Verified
Journal Article
Open access
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AQAlda Quattrone
Alda Quattrone
IPIvan Picozzi
Ivan Picozzi
ELEmanuele Lubian
Emanuele Lubian
Nour Elhouda FehriNour Elhouda Fehri
Nour Elhouda Fehri
Laura MenchettiLaura Menchetti
Laura Menchetti
Giulio CuroneGiulio Curone
Giulio Curone
Birds exhibit naturally high blood glucose concentrations, a physiological trait that, unlike in mammals, does not lead to typical pathological consequences such as diabetes mellitus. This review explores the unique features of glucose metabolism in birds, with a particular focus on the anatomy and function of the avian pancreas, the roles of key hormones such as insulin and glucagon, as well as the distinctive mechanisms of glucose absorption and utilization. Evidence suggests a dominant role of glucagon over insulin, along with adaptations such as insulin resistance and antioxidant defenses, which may contribute to birds’ apparent resilience to hyperglycemia-related complications. Despite these adaptations, cases of diabetes mellitus have been reported, primarily as secondary to other pathologies, including pancreatitis, hemochromatosis, infections, and toxicities. Diagnosis remains challenging due to interspecies variability and the lack of standardized assays. Treatment, mainly via insulin therapy, has shown mixed outcomes, often limited by the underlying disease severity. This review highlights the need for species-specific diagnostic tools and a deeper investigation into the pathophysiology of glucose regulation in birds, aiming to improve clinical outcomes, develop standardized therapies, and ultimately broaden the perspectives of comparative endocrinology.

27 June 2025 in Animals
Verified
Journal Article
Open access
PDF file
Marta CastricaMarta Castrica
Marta Castrica
EAEgon Andoni
Egon Andoni
AQAlda Quattrone
Alda Quattrone
XKXhelil Koleci
Xhelil Koleci
EOEnkeleda Ozuni
Enkeleda Ozuni
Stella AgradiStella Agradi
Stella Agradi
Trace elements, which may have harmful health effects, are present in the environment at varying concentrations. In Albania, data on exposure risks are limited. This study aimed to assess and compare the concentrations of various trace elements (aluminum, arsenic, boron, calcium, cadmium, chromium, copper, iron, potassium, magnesium, manganese, nickel, lead, and zinc) in the hair of cattle and sheep raised in Central Albania (Tirana and Elbasan Counties). Hair samples were collected from 25 cattle and 25 sheep per county and analyzed using inductively coupled plasma–optical emission spectroscopy. Zinc concentrations were significantly higher in cattle than in sheep (p = 0.029), while no differences were observed between counties (p > 0.05), indicating similar environmental conditions. Copper (17.84, 95%CI: 13.63–16.34 and 15.84, 95%CI: 14.00–17.69 mg/kg in cattle, and 15.58, 95%CI: 13.61–17.56 and 14.14, 95%CI: 12.07–16.20 mg/kg in sheep, in Elbasan and Tirana County, respectively), arsenic (2.08, 95%CI: 1.45–1.21 and 1.51, 95%CI: 1.19–1.81 mg/kg in cattle, 1.73, 95%CI: 1.38–2.07 and 1.39, 95%CI: 1.02–1.75 mg/kg in sheep, in Elbasan and Tirana County, respectively), and cadmium (2.36, 95%CI: 1.63–2.07 and 2.00, 95%CI: 1.68–2.32 mg/kg in cattle, 2.00, 95%CI: 1.59–2.40 and 1.71, 95%CI: 1.39–2.02 mg/kg in sheep, in Elbasan and Tirana County, respectively) concentrations exceeded the values reported in the literature, likely due to contamination from local mining and metal processing activities. Further research is needed to determine the sources of contamination and assess potential risks to animal and human health.