Alahyane Hassan

Dr. Alahyane Hassan

orcid

Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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23 June 2022 in Neotropical Entomology
Verified
Journal Article
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IGIchrak Ghalbane
Ichrak Ghalbane
AHAlahyane Hassan
Alahyane Hassan
HAHouda Aboussaid
Houda Aboussaid
NCNor-Eddine Chouikh
Nor-Eddine Chouikh
JCJean Costa
Jean Costa
SMSaid El Messoussi
Said El Messoussi

3 January 2025 in Plants
Verified
Journal Article
Open access
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Mohamed OukninMohamed Ouknin
Mohamed Ouknin
AHAlahyane Hassan
Alahyane Hassan
NANaima AIT AABD
Naima AIT AABD
SESara ELGADI
Sara ELGADI
LLLghazi Lghazi
Lghazi Lghazi
Lhou MajidiLhou Majidi
Lhou Majidi
This study aimed to investigate the chemical composition and bioactivities of essential oils (EOs) from five Moroccan thyme species: Thymus broussonetii subsp. broussonetii, T. maroccanus, T. willdenowii, T. zygis subsp. gracilis, and T. satureioides, collected from various geographical regions. Gas chromatography–mass spectrometry (GC-MS) identified thymol, p-cymene, borneol, γ-terpinene, carvacrol, α-pinene, and camphene as major constituents, with variations across species. Inductively coupled plasma atomic emission spectroscopy (ICP-AES) revealed important levels of calcium (450.6–712.2 mg/kg), potassium (255.4–420.7 mg/kg), magnesium (97.3–150.7 mg/kg), and iron (1.95–15.1 mg/kg). The EOs demonstrated strong antioxidant activity in DPPH, FRAP, and β-carotene bleaching assays. Insecticidal activity against Aphis gossypii revealed the highest efficacy with T. willdenowii EO (LC50 = 6.2 µL/mL), followed by T. maroccanus and T. zygis subsp. gracilis. Additionally, the EOs exhibited potent enzyme inhibitory effects at 1 mg/mL on acetylcholinesterase (83.1–96.4%), tyrosinase (77.5–89.6%), and α-glucosidase (79.4–89.5%). These findings suggest that thyme EOs, particularly from T. willdenowii, T. zygis, and T. maroccanus, are promising candidates for integrated pest management and natural enzyme inhibitors. Their potential applications in medicinal and pharmaceutical fields underscore the need for further research to optimize their use under specific conditions and dosages.

30 August 2024 in Plants
Verified
Journal Article
Open access
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Mohamed OukninMohamed Ouknin
Mohamed Ouknin
AHAlahyane Hassan
Alahyane Hassan
JCJean Costa
Jean Costa
Lhou MajidiLhou Majidi
Lhou Majidi
This study aimed to investigate the variation in the chemical composition of Origanum compactum essential oils (EOs) from four geographically distinct locations. Additionally, we evaluated their antioxidant properties and potential inhibitory effects on acetylcholinesterase (AChE), tyrosinase, and α-glucosidase enzymes and their insecticidal proprieties. Notably, this research also marks the first examination of the mineral composition of O. compactum. The chemical composition was determined using gas chromatography–mass spectrometry (GC-MS), which identified thymol (28.72–80.39%), carvacrol (6.54–61.84%), p-cymene (0.27–8.64%), linalool (1.44–1.96%), and caryophyllene oxide (1.34–1.56%) as the major constituents. Concurrently, inductively coupled plasma atomic emission spectroscopy (ICP-AES) revealed significant levels of macro and microelements, including calcium (295.50–512.20 mg/kg), potassium (195.99–398.45 mg/kg), magnesium (59.70–98.45 mg/kg), and iron (43.55–112.60 mg/kg). The EOs demonstrated notable antiradical activities through DPPH (1,1-diphenyl-2-picrylhydrazyl), FRAP (ferric reducing antioxidant power), and β-carotene bleaching assays. Regarding the insecticidal effect, all studied essential oils showed a significant toxicity against C. capitata adults, and the toxicity was dose and time dependent. The highest insecticidal effect was observed for O. compactum essential oils collected from Gouman (LC50 = 2.515 µL/mL, LC90 = 5.502 µL/mL) after 48 h of treatment. Furthermore, at a concentration of 1 mg/mL, the EOs exhibited strong inhibitory effects against AChE (84.75–94.01%), tyrosinase (84.75–94.01%), and α-glucosidase (79.90–87.80%), highlighting their potential as natural inhibitors of these enzymes. The essential oils of O. compactum contain components that could be used as a basis for synthetizing derivatives or analogs with potential medicinal applications and pest control properties.

18 November 2024 in Nutrients
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Journal Article
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AGAziz Galman
Aziz Galman
Mourad ChikhaouiMourad Chikhaoui
Mourad Chikhaoui
MBMohamed Bouhrim
Mohamed Bouhrim
BEBruno Eto
Bruno Eto
Abdelaaty ShahatAbdelaaty Shahat
Abdelaaty Shahat
KBKhalid Boutoial
Khalid Boutoial
Background/Objectives: The use of dietary supplements (DSs) has become common among fitness enthusiasts, aiming to enhance performance, recovery, and overall well-being. Methods: A cross-sectional study was conducted in the city of Beni Mellal from April to July 2024, assessed dietary practices, motivations for supplement use, and associated adverse effects among 420 survey participants. Results: The majority of dietary supplement users were aged 25–64 and had higher education levels. Colopathy (67.38%) was the most common eating disorder, followed by digestive (59.46%), inflammatory, and rheumatic diseases (53.50%). Dietary supplementation prevalence was 88.1%, with proteins (60.81%), medicinal plants (45.13%), and vitamins (42.70%) being the most consumed. Key motivations included supporting muscle, bone, and joint strength (musculoskeletal) (83.78%) and enhancing heart and lung function for cardiorespiratory health (82.43%). However, 28% of protein users experienced adverse effects, such as myalgia, gastralgia, palpitations, and insomnia. Multivariate linear regression indicated a significant negative association of creatine with effectiveness (β = −0.485, p = 0.001). Conclusions: Overall, while the benefits of dietary and sports practices are evident, the adverse effects associated with protein supplements highlight the necessity for enhanced nutrivigilance and nutritional education to ensure safe supplements.

30 August 2024 in Toxicon
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Journal Article
Closed access
AHAlahyane Hassan
Alahyane Hassan
BEBilal EL-MANSOURY
Bilal EL-MANSOURY
AHAdnane Hakem
Adnane Hakem
AEABDESSAMAD ELMOURID
ABDESSAMAD ELMOURID
DADriss Ait Ali
Driss Ait Ali
AKAbdelaati El Khiat
Abdelaati El Khiat

18 October 2024 in Marine Pollution Bulletin
Verified
Journal Article
Closed access
NCNor-Eddine Chouikh
Nor-Eddine Chouikh
AHAlahyane Hassan
Alahyane Hassan
AMAbdelaziz Mounir
Abdelaziz Mounir
YHYoussef El Hachimi
Youssef El Hachimi
MCMohamed Cheggour
Mohamed Cheggour