The world is talking about the Industry 4.0 or the fourth industrial revolution, that is, the current trend of higher level of automation, digitalization and data exchange in manufacturing technologies. It includes cyber-physical systems, Internet of Things and cloud computing among other technological assets. With more than 5000 sensors, which generate up to 10 GB of data per second, modern aircraft engines are an exponent of what digitalization and the Internet of Aircraft Things could furnish, as part of the upcoming Industry 4.0 revolution, in the aviation industry. This new era has the potential to improve air transport key performance areas. Particularly, in an industry where safety levels are so high and the margins for improvement are extremely tight, this upcoming era might imply a shift in safety improvement. In an attempt to define Aviation 4.0, this chapter discusses the stages of aviation development from basic VFR flight rules at Aviation 1.0 up to Aviation 4.0 where cyber-physical systems are designed to assist humans’ unkind or hazardous work, to take decisions and to complete tasks autonomously. It illustrates the current and future cases of application of Aviation 4.0 to increase the aviation safety, while outlines how they might increase aviation safety levels.

In the last 40 years, the aeronautical industry has managed to move from a specialized sector to a worldwide leading industry. Companies, governments and associations all over the world acknowledge the importance of the aviation industry in supporting global development and the economy. However, aviation will be facing new challenges related to sustainability and performance in a technological environment in evolution. To succeed, the aeronautical industry must keep innovation as one of its main assets. It must master a wide range of technologies and then collaborate to integrate them into an aircraft design and development program. A collaborative approach to innovation is key to achieve these goals. The main purpose of this paper is to analyze the structure of technological innovation networks in the aviation industry and to characterize the map of the “Aviation Technology Space”. Two different approaches and methods are used. In one approach, we performed a bibliometric network analysis of aviation research scientific publications using a keyword co-occurrence analysis method to map the aerospace collaboration structures. Complementarily, we performed a patent analysis to evaluate the innovation capacity of the aviation industry in the cutting-edge technologies previously identified. From the results of this analysis, the paper provides recommendations for future innovation and research policies to allow the sector to fulfill the demanding goals by the year 2050.