In this article the analysis of scientific literature was carried out during which considerable interest of scientists to research of essential oil of Heracléum sosnówskyi — the plants widespread in the Russian Federation, and being weed is noticed. We identified the presence of essential oil in the stems, fruits and leaves of Heracléum sosnówskyi, which grows in three districts of the Moscow region. Also, the quantitative analysis of the content of essential oil in the stems from 0.57 to 0.67 %, in the fruits-from 0.98 to 1.38 %, in the leaves-from 0.87 to 0.93 %.

Background: Vitamin D3 is an important factor for bone metabolism, and its deficiency may affect dental implantation results. Materials and methods: 384 patients with a diagnosis of tooth loss and vitamin D deficiency were examined and treated with dental implants. Vitamin D3 supplements were prescribed by the endocrinologist for all patients in the individual dose. The patients were divided into two equal study groups (n = 192) depending on the dental implantation period: Group 1—operation after blood serum vitamin D3 level normalization; group 2—before reaching the reference level of vitamin D3. Follow-up examinations were performed on the day of dental implantation, 7 days later, 1, 3, 6, and 12 months later, and every 1 year after treatment (up to 10 years). Implant stability and peri-implant tissue condition were assessed with clinical and X-ray diagnostics. Patients also visited an endocrinologist 2 months after the start of the treatment, then every 6 months. Results: The target vitamin D3 level (30–60 ng/mL) (p < 0.001) was achieved in all patients after treatment. At the control examinations, peri-implantitis was diagnosed in 10 patients (2.6%). It was detected in the group of patients with severe vitamin D deficiency and vitamin D deficiency—2 (25%) and 8 (3.4%) patients; respectively (p < 0.05). There was no significant difference between groups for risk of complications or bone quality after treatment. Conclusions: Timely screening of vitamin D3 levels and the appropriate treatment by an endocrinologist in young and middle-aged patients allow for achieving 97.4% dental implantation success for a ten-year period.

Aim: Studying in rabbit model, the bone behavior during the process of osseointegration of dental implants mimicking vitamin deficiency D3.Materials and Methods: Six rabbits received implants in the area of the removed lower first incisor after creating a condition of vitamin D3 deficiency. Afterwards, the examinations were carried out on days 3, 5, 7, 30, and 90 when all animals were removed from the experiment. At that time, a bone block was collected within the installed dental implant, with the intact area and the area of the adjacent tooth. The samples were examined by histomorphometry analysis.Results: In rabbits with vitamin D3 deficiency, dental implants could be osseointegrated by the regeneration of the bone tissues after surgeries. However, a decrease in the number of cells involved in the construction of bone tissue—osteocytes—was recorded in the regenerated bone (40% ± 7%) as compared with the native bone immediately after implantation, before the bone remodeling processes.Conclusions: The study’s results on the rabbit model in vivo confirmed the relationship between vitamin D3 and the process of osseointegration. This in vivo experiment can be the basis for future clinical study.

(1) Background: A decrease in bone mineral density has been noted not only in at-risk patients (e.g., postmenopausal women) but also in young and middle-aged individuals due to changes in lifestyle. The aim of the study was to find a possible correlation for dual-energy X-ray absorptiometry (DXA) and quantitative computed tomography (QCT) with cone beam computed tomography (CBCT) of the jaws. (2) Methods: A total of 24 patients (14 women and 10 men aged 25 to 50 years) with partial secondary tooth loss and vitamin D insufficiency underwent cone beam computed tomography of the jaws and skeletal mineral density assessment using DXA (n = 12) and QCT (n = 12). (3) Results: When conducting CBCT of the jaws, a predominance of bone tissue type D3 (350–850 Hu) on the upper jaw (p > 0.05 (F = 0.68) and D2 (850–1350 Hu) on the lower jaw (p > 0.05 (F = 1) was revealed. According to the results of QCT densitometry of the skeleton, signs of osteopenia were found in four patients (with vitamin D3 deficiency) (33%) according to DXA; signs of osteopenia were found in six patients (with severe deficiency and deficiency of vitamin D3) (50%). The difference between QCT and DXA was not significant (p > 0.05) for each group. The significant strong correlation between CBCT and DXA or QCT was not found (p > 0.05). (4) Conclusions: Primary changes in bone density can be detected earlier in the dental system using cone beam computed tomography of the jaws. At the same time, the question of using a specific densitometry method—DXA or QCT—remains open, as their results correlating with CBCT optical density was not approved.