Luca Comuzzi

Dr. Luca Comuzzi

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Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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LCLuca Comuzzi
Luca Comuzzi
Margherita TumedeiMargherita Tumedei
Margherita Tumedei
APAna Emilia Pontes
Ana Emilia Pontes
APAdriano Piattelli
Adriano Piattelli
Giovanna IezziGiovanna Iezzi
Giovanna Iezzi
Background: The aim of the present study was to compare, in low-density polyurethane blocks, the primary implant stability values (micromobility) and removal torque values of three different implant geometries in two different bone densities representing the structure of the human posterior jaws. Methods: A total of 60 implants were used in the present investigation: twenty implants for each of three groups (group A, group B, and group C), in both polyurethane 10 pcf and 20 pcf densities. The insertion torque, pull-out torque, and implant stability quotient (ISQ) values were obtained. Results: No differences were found in the values of Group A and Group B implants. In both these groups, the insertion torques were quite low in the 10 pcf blocks. Better results were found in the 20 pcf blocks, which showed very good stability of the implants. The pull-out values were slightly lower than the insertion torque values. High ISQ values were found in Group A and B implants. Lower values were present in Group C implants. Conclusions: The present investigation evaluated implants with different geometries that are available on the market, and not experimental implants specifically created for the study. The authors aimed to simulate real clinical conditions (poor-density bone or immediate post-extraction implants) in which knowledge of dental implant features, which may be useful in increasing the primary stability, may help the oral surgeon during the surgery planning.

10 June 2019 in Polymers
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LCLuca Comuzzi
Luca Comuzzi
Giovanna IezziGiovanna Iezzi
Giovanna Iezzi
APAdriano Piattelli
Adriano Piattelli
Margherita TumedeiMargherita Tumedei
Margherita Tumedei
Objectives: The aim of this study was to investigate, in polyurethane foam sheets, the primary implant stability of a NanoShort implant compared to a self-condenser implant and to a standard, conventional implant. Materials and Methods: Three implant designs were evaluated in the present in vitro investigation: The Test implant (NanoShort), the Control A implant (self-condenser), and the Control B implant (standard design). The study was conducted by comparing the insertion torque values, the pull-out strength values, and the resonance frequency analysis (RFA) values of the Test and Control A and B implants inserted in polyurethane foam models of different thicknesses and densities. The foam densities were 10, 20, and 30 pounds per cubic foot (pcf). Three thicknesses of polyurethane foams (1, 2, 3 mm) were evaluated for a total of 640 experimental sites. Results: The Pearson correlation showed a moderate/strong correlation between all study groups (r > 0.3) for insertion torque and pull-out strength levels. Increased stability of the Test implants was obtained in 3 mm polyurethane sheets. The 2.5 and 3.5 mm Test implants presented good stability in 3 mm polyurethane sheets of 20–30 pcf densities. The Control implants showed better results compared to the Test implants in 1, 2, and 3 mm polyurethane sheets with densities of 10, 20, and 30 pcf. Conclusions: The NanoShort dental implant evaluated in this in vitro study showed a high level of stability in some experimental conditions, and could represent a useful tool, especially in the posterior mandible, as an alternative to vertical augmentation procedures.

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LCLuca Comuzzi
Luca Comuzzi
Margherita TumedeiMargherita Tumedei
Margherita Tumedei
Tea RomascoTea Romasco
Tea Romasco
Morena PetriniMorena Petrini
Morena Petrini
Kelvin Ian AfrashtehfarKelvin Ian Afrashtehfar
Kelvin Ian Afrashtehfar
Natalia Di PietroNatalia Di Pietro
Natalia Di Pietro
Short implants were introduced to reduce morbidity, treatment duration, and complex bone regeneration interventions in atrophic jaws and to improve patient-reported outcomes. This study aimed to determine the insertion torque (IT), removal torque (RT), and resonance frequency analysis (RFA) values of ultrashort (3 mm length), short (7 mm length), and standard implants (10 mm length) inserted in 1-, 2-, 3-, and 4-mm thickness polyurethane sheets with densities of 10, 20, and 30 pounds per cubic foot (PCF). Standard-length implants were the gold standard (control). Overall, short-length implant IT values were higher or similar to the control in most experimental conditions. Those inserted into a 3 mm/30 PCF lamina showed the highest IT values, whereas 5 mm diameter ultrashort-length implants inserted into 2 and 3 mm/20 PCF laminas were higher than other implants. RT values followed the same trend and RFA values were more appreciable in short- and standard-length implants in all the scenarios. However, ultrashort-length implants reached a primary stability comparable to that of standard implants in lower thicknesses. In conclusion, although further studies are needed to corroborate this in vitro model with preclinical and clinical studies, our data shed light on short- and ultrashort-length implants geometries to a potential application in critical atrophy of the posterior jaws.

16 November 2023 in Biomedicines
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LCLuca Comuzzi
Luca Comuzzi
MMMario Marioceddia
Mario Marioceddia
Natalia Di PietroNatalia Di Pietro
Natalia Di Pietro
Francesco InchingoloFrancesco Inchingolo
Francesco Inchingolo
Angelo Michele InchingoloAngelo Michele Inchingolo
Angelo Michele Inchingolo
BTBartolomeo Trentadue
Bartolomeo Trentadue
The issue of dental implant placement relative to the alveolar crest, whether in supracrestal, equicrestal, or subcrestal positions, remains highly controversial, leading to conflicting data in various studies. Three-dimensional (3D) Finite Element Analysis (FEA) can offer insights into the biomechanical aspects of dental implants and the surrounding bone. A 3D model of the jaw was generated using computed tomography (CT) scans, considering a cortical thickness of 1.5 mm. Subsequently, Morse cone implant–abutment connection implants were virtually positioned at the model’s center, at equicrestal (0 mm) and subcrestal levels (−1 mm and −2 mm). The findings indicated the highest stress within the cortical bone around the equicrestally placed implant, the lowest stress in the −2 mm subcrestally placed implant, and intermediate stresses in the −1 mm subcrestally placed implant. In terms of clinical relevance, this study suggested that subcrestal placement of a Morse cone implant–abutment connection (ranging between −1 and −2 mm) could be recommended to reduce peri-implant bone resorption and achieve longer-term implant success.

26 June 2022 in Bioengineering
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Simonetta D'ErcoleSimonetta D'Ercole
Simonetta D'Ercole
TDTatiane Cristina Dotta
Tatiane Cristina Dotta
Marzieh Ramezani FaraniMarzieh Ramezani Farani
Marzieh Ramezani Farani
NENiloofar Etemadi
Niloofar Etemadi
Giovanna IezziGiovanna Iezzi
Giovanna Iezzi
Morena PetriniMorena Petrini
Morena Petrini
The objective of this study is to evaluate, in vitro, the microleakage of bacteria of 3 different implant connections for a period of 14 days. 60 dental implants (AoN) (n = 20) were distinguished into three groups, accordingly to the type of connection: External Hexagon (EH), Internal Hexagon (IH), and Cone Morse (CM) connection. All implants were inserted and fixed on sterile special vinyl support. Ten fixtures for each group were inoculated in the internal platform with 1.0 μL of Streptococcus oralis (SO) and the other ten with the same amount of Pseudomonas aeruginosa (PA). The penetration of bacterial suspension into the surrounding solution was determined by the observation of the turbidity of the broth. Five implants for each sub-group were randomly observed at SEM, to verify the correct fitting of the abutments. Considering the total of the samples analyzed, CM showed significantly lower bacterial contamination, with respect to IH. In particular, bacterial contamination was found in 45%, 55%, and 20% of EH, IH, and CM, respectively. Analyzing results for the type of inoculated bacteria, P. aeruginosa showed a higher ability to contaminate all the connections, with respect to S. oralis.

LCLuca Comuzzi
Luca Comuzzi
Margherita TumedeiMargherita Tumedei
Margherita Tumedei
CDCamillo D'Arcangelo
Camillo D'Arcangelo
APAdriano Piattelli
Adriano Piattelli
Giovanna IezziGiovanna Iezzi
Giovanna Iezzi
Background: Several different dental implant microgeometries have been investigated in the literature for use in low-density bone sites. The polyurethane solid rigid blocks represent an optimal in vitro study model for dental implants, because their composition is characterized by symmetrical linear chains of monomers of hexa-methylene sequences producing a self-polymerization process. The aim of the present investigation was to evaluate the primary stability of cylindrical and tapered implants positioned into low-density polyurethane solid rigid blocks. Materials and Methods: Two different macrogeometries, cylindrical (4 mm diameter and 10 mm length) and tapered dental implants (4.20 mm diameter and 10 mm length), were investigated in the present study. The implants were inserted into 10 PCF and 20 PCF polyurethane blocks, with and without an additional cortical layer. The insertion torque (IT) values, the removal torque values (RTVs), and the resonance frequency analysis (RFA) values were measured and recorded. Results: A total of 80 sites were tested, and a significant increased primary stability (PS) was detected in favour of tapered dental implants when compared to cylindrical implants in all experimental conditions (p < 0.05). Higher IT, RT, and RFA values were measured in tapered implants in 10 and 20 PCF polyurethane blocks, both with and without the additional cortical layer. Conclusions: Both implants showed sufficient primary stability in poor density substrates, while, on the other hand, the tapered microgeometry showed characteristics that could also lead to clinical application in low-density posterior maxillary sites, even with a drastically decreased bone cortical component.