Milica Curcic

Dr. Milica Curcic

orcid

Research Focus & Metrics

Academic Career Length

12Years (2015-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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16 September 2025 in Pharmaceutics
Verified
Journal Article
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MCMilica Curcic
Milica Curcic
Branka HadžićBranka Hadžić
Branka Hadžić
MGMartina Gilic
Martina Gilic
ZLZorica Z Lazarevic
Zorica Z Lazarevic
Andjelija IlićAndjelija Ilić
Andjelija Ilić
Background/Objectives: Barium titanate (BaTiO3)-based nanocarriers have emerged as versatile and promising platforms for targeted drug delivery, owing to their unique combination of biocompatibility, piezoelectric and ferroelectric properties, as well as responsiveness to external stimuli. These multifunctional ceramic nanoparticles can be precisely engineered to enable spatiotemporally controlled release of therapeutic agents, triggered by physical stimuli such as ultrasound, light, magnetic fields, temperature changes, and pH variations. Such an approach enhances treatment efficacy while reducing systemic side effects. Methods: This review provides a comprehensive overview of the latest advancements in the development and biomedical application of BaTiO3-based nanocarriers. Special emphasis is placed on modern synthesis strategies, surface functionalization methods, and the integration of BaTiO3 with other functional nanomaterials to create hybrid systems with improved therapeutic performance. Key challenges in clinical translation are also discussed, including biocompatibility assessment, biodistribution, and regulatory requirements. Conclusions: BaTiO3-based nanocarriers show promise as materials well suited for advanced biomedical applications. The paper concludes with an outline of future research directions aimed at optimizing these advanced nanosystems for precision and personalized medicine, with applications in oncology, anti-infective therapy, and regenerative medicine.

5 February 2022 in Journal of Raman Spectroscopy
Verified
Journal Article
Closed access
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JTJelena Trajic
Jelena Trajic
MCMilica Curcic
Milica Curcic
MLMariano Casas Luna
Mariano Casas Luna
MRMaja Romcevic
Maja Romcevic
MRMichaela Remesova
Michaela Remesova
KDK. Dvorek
K. Dvorek

1 July 2025 in Atmosphere
Verified
Journal Article
Open access
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FSFathya Shabek
Fathya Shabek
PKPredrag Kolarz
Predrag Kolarz
ICIgor Celikovic
Igor Celikovic
MCMilica Curcic
Milica Curcic
AJAco Janićijević
Aco Janićijević
Radon’s radioactive decay is the main natural source of small air ions near the ground. Its exhalation from soil is affected by meteorological factors, while aerosol pollution reduces air ion concentrations through ion-particle attachment. This study aimed to analyze correlations between radon, ions, and air pollution under varying conditions and to assess potential health impacts. Measurements were taken at two sites: in early autumn at a suburban part of Belgrade with relatively clean air, and in late autumn in central Belgrade under polluted conditions, with low temperatures and high humidity. Parameters measured included radon, small air ions, particle size distribution, PM mass concentration, temperature, humidity, and pressure. Results showed lower radon concentrations in late autumn due to high soil moisture and absence of nocturnal inversions. Radon and air ion concentrations exhibited a strong positive correlation for both polarities under suburban conditions, whereas measurements in the urban setting revealed a weak negative correlation, despite radon concentrations in soil gas being approximately equal at both sites. Small ion levels were also reduced, mainly due to suppressed radon exhalation and increased aerosol concentrations, especially ultrafine particles. A strong negative correlation (r < −0.5) was found between small air ion concentrations and particle number concentrations in the 20–300 nm range, while larger particles (300–1000 nm and >1 µm) showed weak or no correlation due to their lower and more stable concentrations. In contrast, early autumn measurements showed a diurnal cycle of radon, characterized by nighttime maxima and daytime minima, unlike the consistently low values observed in late autumn.

2 April 2026 in Microplastics
Verified
Journal Article
Open access
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MCMilica Curcic
Milica Curcic
ISIvana M Stajcic
Ivana M Stajcic
Dusica StojanovicDusica Stojanovic
Dusica Stojanovic
Branka HadžićBranka Hadžić
Branka Hadžić
PMP. Mitric
P. Mitric
PKPredrag Kolarz
Predrag Kolarz
Heterogeneous photocatalysis increasingly requires rapid polymer degradation tests relevant to aqueous conditions. In this study, a multi-technique approach was developed to monitor the early-stage photo-oxidation of polyethylene (PE) and polystyrene (PS) microplastics in an aqueous ZnO–TiO2 suspension under combined ultraviolet A and ultraviolet B (UV-A/B) irradiation. The changes were analyzed by ATR-FTIR and Raman spectroscopy, DSC, and gravimetric measurements. For PE, the carbonyl index increased from 0.0189 to 0.1350 after 12 h, mass loss reached 16.98%, and crystallinity decreased from 32.05% to 25.36% after 8 h. The Raman spectra of PE showed band broadening and intensity redistribution, indicating increasing structural disorder. In contrast, PS showed weaker Raman changes, while FTIR revealed a non-monotonic carbonyl-index response, and DSC showed a 2.2 °C increase in Tg after 12 h. Gravimetric analysis also showed measurable mass loss in PS, reaching 18.62% after 12 h. The results demonstrate that the combined use of ATR-FTIR, Raman, DSC, and gravimetry enables reliable distinction between early oxidation, surface modification, and material erosion in photocatalytically treated microplastics.

18 June 2025 in Coatings
Verified
Journal Article
Open access
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ISIvana M Stajcic
Ivana M Stajcic
VRVesna Radojević
Vesna Radojević
ZLZorica Z Lazarevic
Zorica Z Lazarevic
MCMilica Curcic
Milica Curcic
Branka HadžićBranka Hadžić
Branka Hadžić
ASAleksandar Stajcic
Aleksandar Stajcic
Dicyclopentadiene (DCPD)–poly(methyl methacrylate) (PMMA) core–shell fibers were fabricated via coaxial electrospinning to develop a self-healing polymer composite. A PMMA shell containing a first-generation Grubbs catalyst was co-spun with a DCPD core at 0.5 mL h−1 and 28 kV, yielding smooth, cylindrical fibers. The diameter range of nanofibers was 300–900 nm, with 95% below 800 nm, as confirmed by FESEM image analysis. FTIR spectroscopy monitored shell integrity via the PMMA C=O stretch and core polymerization via the trans-C=C bands. The high presence of the 970 cm−1 band in the healed nanofiber mat and the minor appearance in the uncut core–shell mat demonstrated successful DCPD polymerization mostly where the intended damage was. The optical clarity of PMMA enabled the direct monitoring of healing progress via optical microscopy. The presented findings demonstrate that PMMA can retain a liquid active core and catalyst to form a polymer layer on a damaged site and could be used as a model material for other self-healing systems that require healing monitoring.

26 May 2026 in Microplastics
Verified
Journal Article
Open access
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ABAleksandra Božić
Aleksandra Božić
Branka HadžićBranka Hadžić
Branka Hadžić
ZLZorica Z Lazarevic
Zorica Z Lazarevic
MCMilica Curcic
Milica Curcic
Sunlight-driven UV weathering is a major transformation pathway of environmental microplastics, promoting surface oxidation, molecular degradation, embrittlement, and progressive fragmentation toward smaller size fractions. However, comparisons across studies remain difficult because weathering is often described using descriptors that probe different aspects of degradation without being clearly distinguished. Surface-sensitive oxidation metrics, such as carbonyl or oxidation indices (CI/OI), are frequently emphasized, whereas fragmentation and embrittlement are more directly governed by bulk molecular-weight loss, mechanical weakening, and particle-size evolution. This review examines UV weathering of common polymers through a coupled chemico-mechanical perspective relevant to the micro-to-nano transition. We distinguish surface chemical descriptors, bulk molecular and mechanical descriptors, and fragmentation-related metrics, and critically assess the analytical methods used to measure them, including FTIR, Raman spectroscopy, GPC/SEC, thermal methods, mechanical testing, and particle-size analyses. We argue that no single metric is sufficient to describe weathering progression, and that meaningful interpretation requires joint reporting of oxidation state, Mn/Mw changes, mechanical deterioration where available, and particle-size distribution as a function of cumulative or spectrum-weighted UV dose. We further propose a minimal QA/QC reporting framework including UV metadata, temperature, oxygen availability, blanks, replicates, recovery tests, and matrix-specific detection limits. By separating what different methods actually probe and linking them to fragmentation mechanisms, this review provides a more operational basis for interpreting UV-aged microplastics in environmental sampling and biomonitoring.