Vasileios P. Giannoudis

Dr. Vasileios P. Giannoudis

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Research Focus & Metrics

Academic Career Length

9Years (2018-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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13 June 2018 in JBJS Essential Surgical Techniques
Verified
Journal Article
Closed access
TTTheodoros H Tosounidis
Theodoros H Tosounidis
VGVasillios P. Giannoudis
Vasillios P. Giannoudis
Nikolaos K. KanakarisNikolaos K. Kanakaris
Nikolaos K. Kanakaris
VGVasileios P. Giannoudis
Vasileios P. Giannoudis
The Kocher-Langenbeck approach is the workhorse for the reduction and fixation of hip fractures that require fixation via a posterior approach1,2. Review the patient's general condition and imaging studies, plan the sequence of reduction and fixation, and make sure that all of the necessary equipment is available. Induce anesthesia, administer intravenous antibiotics as per local hospital protocol, apply antiembolism stockings, and insert a Foley catheter to the bladder. Make an incision that is 15 to 20 cm long and has 2 parts (proximal and distal), which are centered over the greater trochanter. The reconstruction of posteriorly based fractures depends on the specific fracture type, and the goal is to provide stable column fixation and anatomical reconstruction of the acetabular articular surface, with column fixation performed before the reconstruction of the posterior wall. Meticulous hemostasis, application of drains, and watertight closure are the final steps of the operation. The Kocher-Langenbeck approach is the workhorse for the surgical management of acetabular fractures and provides sufficient access to the majority of posterior based acetabular fractures15.

27 June 2018 in JBJS Essential Surgical Techniques
Verified
Journal Article
Closed access
TTTheodoros H Tosounidis
Theodoros H Tosounidis
VGVasillios P. Giannoudis
Vasillios P. Giannoudis
Nikolaos K. KanakarisNikolaos K. Kanakaris
Nikolaos K. Kanakaris
VGVasileios P. Giannoudis
Vasileios P. Giannoudis
The ilioinguinal approach is the standard approach for the open reduction and internal fixation of the majority of displaced, anteriorly based acetabular fractures as it offers wide access to the acetabulum, is extensile, and has been associated with enhanced recovery. Review the patient's general condition and imaging studies and plan the sequence of reduction and fixation. Position the patient supine on the fracture table, induce anesthesia, prepare the surgical field, administer intravenous antibiotics, and apply traction. Make a long curvilinear incision over the affected lower flank, develop the 3 working windows, and reduce and stabilize the fracture while protecting the neurovascular structures and the bladder (Video 2). For reduction of a both-column acetabular fracture, connect the mobile parts of the acetabulum to the iliac segment that is attached to the sacrum, noting that, in most cases, the usual sequence involves the reduction of the anterior column to the intact ilium followed by the reduction of the posterior column (Video 7). Perform meticulous hemostasis, apply drains, and ensure watertight closure, which are the final steps of the operation (Video 8). The ilioinguinal approach remains 1 of the standard approaches for the management of acetabular fractures10.

18 March 2021 in HIP International
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Journal Article
Open access
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PPPurva V Patel
Purva V Patel
VGVasileios P. Giannoudis
Vasileios P. Giannoudis
SPSamantha Palma
Samantha Palma
SGStephen P Guy
Stephen P Guy
JPJeya Palan
Jeya Palan
BDBernard H. Van Duren
Bernard H. Van Duren
Advice given to patients on driving resumption after total hip arthroplasty (THA) is inconsistent. Due to a lack of clear guidelines, surgeons’ recommendations range between 4–8 weeks after surgery to resume driving. Delays in driving return can have detrimental social and economic impact. However, it is important to ensure patients only resume driving once safe. This study presents a systematic review and meta-analysis of driving simulation studies after THA to establish when patients can safely return to driving postoperatively. A systematic review and meta-analysis using PRISMA guidelines was undertaken. Titles and abstracts were screened for inclusion, data was extracted, and studies assessed for bias risk. Review Manager, was used for statistical analysis. Values for brake reaction time (BRT) were included for meta-analysis. 14 articles met the inclusion criteria. Of these, 7 measured BRT and were included in the meta-analysis. Pooled means of both right and left THA showed BRT around or above preoperative baseline at 1 week, 2 weeks and 3 weeks, and below baseline at 6 weeks, 12 weeks, 32 weeks and 52 weeks. Of these, the pooled means at 6, 32, and 52 weeks were significant (p < 0.05). Studies not meeting meta-analysis inclusion criteria were included in a qualitative analysis, examining self-reported postoperative driving return times which ranged from 6 days to over a year or in rare cases, never. Majority of patients (n = 960) self-reported driving return within approximately 6 weeks (pooling of mean values 32.9 days). The mean return to driving time recommended in the literature was 4.5 weeks. Based upon BRT meta-analysis, a return to baseline braking performance was noted at 6 weeks postoperatively. However, driving is a complex skill, and patient recommendation should be individualised based on factors such as vehicle transmission type, THA technique, surgical side, medication and comorbidities.

22 January 2021 in Journal of Clinical Medicine
Verified
Journal Article
Open access
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TTTheodoros H Tosounidis
Theodoros H Tosounidis
CHColin Holton
Colin Holton
VGVasileios P. Giannoudis
Vasileios P. Giannoudis
Nikolaos K. KanakarisNikolaos K. Kanakaris
Nikolaos K. Kanakaris
RWRobert Michael West
Robert Michael West
Peter V GiannoudisPeter V Giannoudis
Peter V Giannoudis
Nonunion remains a major complication of the management of long bone fractures. The primary aim of the present study was to investigate whether raised levels of C-reactive protein (CRP) and white blood cell count (WBC), in the absence of clinical signs, are correlated with positive intraoperative tissue cultures in presumptive aseptic long-bone nonunions. Infection was classified as positive if any significant growth of microorganisms was observed from bone/tissue samples sent from the theater at the time of revision surgery. Preoperatively all patients were investigated with full blood count, white blood count differential as well as C-reactive protein (CRP). A total of 105 consecutive patients (59 males) were included in the study, with an average age of 46.76 years (range 16–92 years) at the time of nonunion diagnosis. The vast majority were femoral (56) and tibial (37) nonunions. The median time from the index surgical procedure to the time of nonunion diagnosis was 10 months (range 9 months to 10 years). Positive cultures revealed a mixed growth of microorganisms, with coagulase-negative Staphylococcus (56.4%) being the most prevalent microorganism, followed by Staphylococcusaureus (20.5%). Pseudomonas, Methicillin-Resistant Staphylococcus aureus (MRSA), coliforms and micrococcus were present in the remainder of the cases (23.1%). Overall, the risk of infection with normal CRP levels (<10 mg/L) was 21/80 = 0.26. Elevated CRP levels (≥10 mg/L) increased the risk of infection to 0.72. The relative risk given a positive CRP test was RR = 0.72/0.26 = 2.74. Overall, the WBC count was found to be an unreliable marker to predict infection. Solid union was achieved in all cases after an average of 6.5 months (3–24 months) from revision surgery. In patients with presumed aseptic long bone nonunion and normal CRP levels, the risk of underlying low-grade indolent infection can be as high as 26%. Patients should be made aware of this finding, which can complicate their treatment course and outcomes.

8 November 2023 in Injury
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Journal Article
Closed access
JMJorge Mayor
Jorge Mayor
VBVera Birgel
Vera Birgel
JCJan-Dierk Clausen
Jan-Dierk Clausen
GAGökmen Aktas
Gökmen Aktas
SSStephan Sehmisch
Stephan Sehmisch
Emmanouil LiodakisEmmanouil Liodakis
Emmanouil Liodakis

19 January 2023 in European Journal of Orthopaedic Surgery & Traumatology
Verified
Journal Article
Open access
PDF file
VGVasileios P. Giannoudis
Vasileios P. Giannoudis
PRPaul Lambton Rodham
Paul Lambton Rodham
AAAntony Antypas
Antony Antypas
NMNiki Mofori
Niki Mofori
GCGeorge D. Chloros
George D. Chloros
Peter V GiannoudisPeter V Giannoudis
Peter V Giannoudis
Introduction Carbon fibre-reinforced polyetheretherketone (CFR-PEEK) plates represent an exciting development within trauma and orthopaedic surgery, offering advantages including radiolucency, material properties similar to bone, and lack of localised tissue reaction. As more call for trials examining their use, there is no data available as to the acceptability of these implants to patients. This study aimed to therefore examine the acceptability of CFR-PEEK plates to patients undergoing fracture surgery. Methods This was a prospective cross-sectional survey of patients undergoing surgery for a fracture of the ankle, distal femur, distal radius, or proximal humerus. Once a decision had been made to pursue operative fixation with a plate, patients were provided with descriptions of both CFR-PEEK and stainless steel and titanium metal implants alongside the current clinical evidence. All patients undertook a questionnaire examining their views as to the advantages and disadvantages of CFR-PEEK plates, and whether they would be happy to participate in a trial comparing both. Results Ninety-nine patients were happy to participate (64 females, mean age 50). Eighty-seven patients reported that they would want a CFR-PEEK implant for their fracture, and 76 reported that they would be willing to participate in an RCT comparing their use. Commonly reported advantages included radiolucency, low weight and biocompatibility. Disadvantages reported included cost and concerns regarding durability. Conclusions This study demonstrates that CFR-PEEK implants would be acceptable to patients undergoing fracture surgery, with high numbers of patients stating that they would be willing to participate in a randomised study examining their use.