Esben Bolvig Mark

Mr. Esben Bolvig Mark

orcid

Research Focus & Metrics

Academic Career Length

10Years (2017-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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20 August 2018 in Neurogastroenterology & Motility
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Journal Article
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EMEsben Bolvig Mark
Esben Bolvig Mark
JPJakob Lykke Poulsen
Jakob Lykke Poulsen
AHAnne‐Mette Haase
Anne‐Mette Haase
MEMarie Espersen
Marie Espersen
TGTine Gregersen
Tine Gregersen
ADAsbjørn M. Drewes
Asbjørn M. Drewes

23 November 2022 in Neurogastroenterology & Motility
Verified
Journal Article
Open access
DBDavide Bertoli
Davide Bertoli
EMEsben Bolvig Mark
Esben Bolvig Mark
DLDonghua Liao
Donghua Liao
CBChristina Brock
Christina Brock
JFJens Brøndum Frøkjær
Jens Brøndum Frøkjær
ADAsbjørn M. Drewes
Asbjørn M. Drewes
Background: Gastric motility and accommodation have a critical role in maintaining normal gastrointestinal homeostasis. Different modalities can be adopted to quantify those processes, that is, scintigraphy to measure emptying time and intragastric Barostat for accommodation assessment. However, magnetic resonance imaging (MRI) can assess the same parameters noninvasively without ionizing radiation. Our study aimed to develop a detailed three‐dimensional (3D) MRI model of the stomach to describe gastric volumes, surface areas, wall tension distribution, and interobserver agreement.Methods: Twelve healthy volunteers underwent an MRI protocol of six axial T2‐weighted acquisitions. Each dataset was used to construct a 3D model of the stomach: First, the volumes of the whole stomach, gastric liquid, and air were segmented. After landmark placing, a raw 3D model was generated from segmentation data. Subsequently, irregularities were removed, and the model was divided into compartments. Finally, surface area and 3D geometry parameters (inverse curvatures) were extracted. The inverse curvatures were used as a proxy for wall tension distribution without measuring the intragastric pressure.Key Results: The model was able to describe changes in volume and surface geometry for each compartment with a distinct pattern in response to filling and emptying. The surface tension was distributed nonhomogeneously between compartments and showed dynamical changes at various time points.Conclusion & Inferences: The presented model offers a detailed tool for evaluating gastric volumes, surface geometry, and wall tension in response to filling and emptying and will provide insights into gastric emptying and accommodation in diseases such as diabetic gastroparesis.

8 October 2018 in Abdominal Radiology
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JKJohannes Peter Kipp
Johannes Peter Kipp
SOSøren Schou Olesen
Søren Schou Olesen
EMEsben Bolvig Mark
Esben Bolvig Mark
LFLida Changiziyan Frederiksen
Lida Changiziyan Frederiksen
ADAsbjørn M. Drewes
Asbjørn M. Drewes
JFJens Brøndum Frøkjær
Jens Brøndum Frøkjær

1 February 2021 in Clinical Nutrition
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Journal Article
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RTRandi Tobberup
Randi Tobberup
ACAndreas Carus
Andreas Carus
HRHenrik H. Rasmussen
Henrik H. Rasmussen
UFUrsula Gerda Falkmer
Ursula Gerda Falkmer
MJMartin G. Jørgensen
Martin G. Jørgensen
MHMette Holst
Mette Holst

6 May 2019 in Scientific Reports
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Journal Article
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MNMuhammad Samran Navid
Muhammad Samran Navid
DLDina Lelic
Dina Lelic
Imran Khan NiaziImran Khan Niazi
Imran Khan Niazi
KHKelly Holt
Kelly Holt
EMEsben Bolvig Mark
Esben Bolvig Mark
Heidi HaavikHeidi Haavik
Heidi Haavik
The objectives of the study were to investigate changes in pain perception and neural activity during tonic pain due to altered sensory input from the spine following chiropractic spinal adjustments. Fifteen participants with subclinical pain (recurrent spinal dysfunction such as mild pain, ache or stiffness but with no pain on the day of the experiment) participated in this randomized cross-over study involving a chiropractic spinal adjustment and a sham session, separated by 4.0 ± 4.2 days. Before and after each intervention, 61-channel electroencephalography (EEG) was recorded at rest and during 80 seconds of tonic pain evoked by the cold-pressor test (left hand immersed in 2 °C water). Participants rated the pain and unpleasantness to the cold-pressor test on two separate numerical rating scales. To study brain sources, sLORETA was performed on four EEG frequency bands: delta (1–4 Hz), theta (4–8 Hz), alpha (8–12 Hz) and beta (12–32 Hz). The pain scores decreased by 9% after the sham intervention (p < 0.05), whereas the unpleasantness scores decreased by 7% after both interventions (p < 0.05). sLORETA showed decreased brain activity following tonic pain in all frequency bands after the sham intervention, whereas no change in activity was seen after the chiropractic spinal adjustment session. This study showed habituation to pain following the sham intervention, with no habituation occurring following the chiropractic intervention. This suggests that the chiropractic spinal adjustments may alter central processing of pain and unpleasantness.