Alexandra Steinerbrunner-Nagy

Alexandra Steinerbrunner-Nagy

orcid

Research Focus & Metrics

Academic Career Length

3Years (2024-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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17 September 2024 in Polymers
Verified
Journal Article
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EPEmese Paari-Molnar
Emese Paari-Molnar
KKKinga Kardos
Kinga Kardos
RTRoland Told
Roland Told
ISImre Simon
Imre Simon
NSNIITN SAHAI
NIITN SAHAI
Peter MarotiPeter Maroti
Peter Maroti
Conductive polymer composites are commonly present in flexible electrodes for neural interfaces, implantable sensors, and aerospace applications. Fused filament fabrication (FFF) is a widely used additive manufacturing technology, where conductive filaments frequently contain carbon-based fillers. In this study, the static and dynamic mechanical properties and the electrical properties (resistance, signal transmission, resistance measurements during cyclic tensile, bending and temperature tests) were investigated for polylactic acid (PLA)-based, acrylonitrile butadiene styrene (ABS)-based, thermoplastic polyurethane (TPU)-based, and polyamide (PA)-based conductive filaments with carbon-based additives. Scanning electron microscopy (SEM) was implemented to evaluate the results. Cytotoxicity measurements were performed. The conductive ABS specimens have a high gauge factor between 0.2% and 1.0% strain. All tested materials, except the PA-based conductive composite, are suitable for low-voltage applications such as 3D-printed EEG and EMG sensors. ABS-based and TPU-based conductive composites are promising raw materials suitable for temperature measuring and medical applications.

20 January 2025 in Cells
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Journal Article
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JBJudit Bóvári-Biri
Judit Bóvári-Biri
JMJudith Anna Miskei
Judith Anna Miskei
KZKövér Zsanett
Kövér Zsanett
ASAlexandra Steinerbrunner-Nagy
Alexandra Steinerbrunner-Nagy
KKKinga Kardos
Kinga Kardos
Judit E PongraczJudit E Pongracz
Judit E Pongracz
Maxillofacial bone defects can have a profound impact on both facial function and aesthetics. While various biomaterial scaffolds have shown promise in addressing these challenges, regenerating bone in this region remains complex due to its irregular shape, intricate structure, and differing cellular origins compared to other bones in the human body. Moreover, the significant and variable mechanical loads placed on the maxillofacial bones add further complexity, especially in cases of difficult-to-treat medical conditions. This review provides a brief overview of medication-related osteonecrosis of the jaw (MRONJ), highlighting the medication-induced adverse reactions and the associated clinical challenges in treating this condition. The purpose of this manuscript is to emphasize the role of biotechnology and tissue engineering technologies in therapy. By using scaffold materials and biofactors in combination with autologous cells, innovative solutions are explored for the repair of damaged facial bones. The ongoing search for effective scaffolds that can address these challenges and improve in vitro bone preparation for subsequent regeneration in the maxillofacial region remains critical. The primary purpose of this review is to spotlight current research trends and novel approaches in this area.

11 October 2025 in Macromolecular Materials and Engineering
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Journal Article
Open access
KKKinga Kardos
Kinga Kardos
EPEmese Paari-Molnar
Emese Paari-Molnar
RTRoland Told
Roland Told
Adél LenAdél Len
Adél Len
PSPéter Szabó
Péter Szabó
Peter MarotiPeter Maroti
Peter Maroti
Material extrusion (MEX), particularly Fused Filament Fabrication (FFF), is a widely used 3D printing technology, with growing interest in composite materials due to their broad range of applications. This study focuses on commercially available copper‐ and bronze‐filled polylactic‐acid (PLA) composites printed with FFF technology and on providing guidance for future practical applications, particularly in the biomedical field and 4D printing. In this research, static and dynamic mechanical tests, scanning electron microscopic imaging, and electric resistance measurements were conducted, and the thermal properties were determined by thermal conductivity measurements and differential scanning calorimetry, and thermogravimetric analysis (DSC‐TGA). Cytotoxicity was assessed using an A549 cell viability assay. The results show that the material's brittleness increases in proportion to the volume percentage of metal particles; among the copper composites FormFutura MetalFil – Classic copper (29.14 vol.%) had the lower tensile strength (15.4 MPa ± 0.17 MPa), while for bronze composites, the tensile strength was lower for ColorFabb BronzeFill (33.64 vol.%, 17.7 MPa ± 0.54 MPa). Furthermore, these composites have no cytotoxic effect in short‐term contact, and their enhanced thermal conductivity over traditional prosthetic materials makes them promising candidates for the development of prostheses intended to mitigate thermal discomfort.

Verified
Journal Article
Open access
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BKBela Kolarovszki
Bela Kolarovszki
ASAlexandra Steinerbrunner-Nagy
Alexandra Steinerbrunner-Nagy
DFDorottya Frank
Dorottya Frank
GDGabor Sandor Decsi
Gabor Sandor Decsi
AMAttila Mühl
Attila Mühl
Kinga TurzóKinga Turzó
Kinga Turzó
Background: Soft tissue stability around dental implant abutments is critical for maintaining a functional peri-implant seal. Yellow anodization is used to improve the aesthetic and surface characteristics of titanium abutments, yet its epithelial effects under more physiologically relevant 3D conditions remain insufficiently explored. Objective: To develop a 3D bioprinted in vitro peri-implant mucosa model and to compare epithelial cell responses on yellow anodized versus turned titanium abutment surfaces. Methods: Commercial Grade 5 (Ti6Al4V) titanium abutments were anodized and compared with turned controls. A collagen-based 3D bioprinted “collar-like” construct incorporating YD-38 epithelial cells was fabricated using a custom holder system to simulate peri-implant mucosal contact. Samples were cultured for 14 and 21 days. Cell distribution and morphology were assessed by optical microscopy and HE staining, while cytoskeletal organization was evaluated by TRITC-phalloidin/Hoechst staining and confocal microscopy. Quantitative fluorescence analysis was performed at 21 days. Results: Both surfaces supported epithelial coverage in the 3D environment. Anodized specimens showed more pronounced actin cytoskeletal organization and the presence of actin-rich, filamentous cellular extensions compared with turned controls. Quantitative image analysis demonstrated significantly higher TRITC-phalloidin signal intensity at 21 days on anodized samples (p < 0.001). Conclusions: Within the limitations of a 3D epithelial in vitro model using YD-38 cells, yellow anodization was associated with enhanced epithelial cytoskeletal organization compared with turned titanium. The presented 3D bioprinted platform may serve as a practical in vitro tool for screening abutment surface modifications relevant to peri-implant soft tissue integration.