Introduction. The article analyzes modern innovative approaches to the preservation and improvement of women’s reproductive health in the Republic of Kazakhstan and worldwide. The authors aimed to provide a scientific justification for the role of medical, digital, and organizational-social innovations in increasing the effectiveness of the reproductive health care system, and to identify priority directions for their further development in the context of demographic and medico-social challenges. Objective. To analyze modern innovative approaches to protecting and improving women’s reproductive health in the Republic of Kazakhstan and global practice, and to identify priority areas for their development. Materials and Methods. The research materials include official statistical data and analytical reports from the World Health Organization and UNFPA, regulatory and legal documents, state programs of the Republic of Kazakhstan, and the results of domestic and international scientific studies in reproductive medicine. The study employs methods of systemic and comparative analysis, the generalization of scientific data, and content analysis of national and international reproductive health protection strategies. Results. The study demonstrated that the implementation of integrated primary health care models, screening and preventive programs, telemedicine, assisted reproductive technologies, and digital educational platforms contributes to improved accessibility and quality of medical care, early identification of risk factors, reduction of maternal and perinatal mortality, and the formation of responsible reproductive behavior among women and young people. Conclusion. Further development of the women’s reproductive health care system requires expanding scientifically grounded and personalized approaches, improving prognostic and screening programs, fostering interdisciplinary cooperation, and sustainable state support for innovative solutions aimed at preserving reproductive potential and ensuring the demographic sustainability of the Republic of Kazakhstan.

Background/Objectives: Menstrual health in adolescence is influenced by nutritional, developmental, and psychosocial factors, yet integrated school-based evidence from Central Asia is limited. We assessed recorded anthropometric, menstrual/reproductive, and psychosocial indicators among adolescent girls in southern Kazakhstan and evaluated factors associated with a prespecified composite menstrual/reproductive outcome. Methods: We conducted a cross-sectional secondary analysis of a non-public school health screening database containing 5197 participant records from 2025. After removal of 946 exact duplicate copies, 4251 unique records of girls aged 12–18 years remained. We present prevalence estimates with Wilson 95% confidence intervals (CIs). We estimated adjusted prevalence ratios (aPRs) using modified Poisson regression with robust standard errors clustered by recorded school field. Results: Mean age was 15.03 ± 1.23 years and mean BMI was 20.36 ± 3.36 kg/m². The source form used fixed adult BMI categories; these are reported descriptively and are not interpreted as pediatric nutritional diagnoses. At least one non-reference menstrual or reproductive indicator was recorded in 24.1% of participants; severe menstrual pain and stress were each recorded in 6.9%. Stress was associated with any menstrual/reproductive abnormality (aPR 2.05, 95% CI 1.65–2.54) and with severe menstrual pain (aPR 3.27, 95% CI 2.39–4.46). Unsatisfactory nutrition was also associated with the composite outcome (aPR 1.64, 95% CI 1.35–2.00). Conclusions: Recorded menstrual/reproductive concerns were frequent in this screened sample, and stress showed consistent associations with menstrual outcomes. Because anthropometric categories were based on adult cut points and several screening items were not validated instruments, interpret the findings as descriptive and hypothesis-generating rather than as population prevalence or causal estimates.