Background and Objectives: the mandibular foramen is an essential anatomic landmark in performing various dental and surgical procedures, including inferior alveolar nerve block (IANB). However, its position may vary based on the individual morpho-functional features of the skull and face. This study aims to conduct a personalized assessment of the location of the mandibular foramen in various shapes of skulls, faces, and mandibles. Materials and Methods: this anatomic morphometric cross-sectional study was performed using one hundred and six (n = 106) certified human cadaver heads of both sexes. The cranial index (CI) and Izard’s facial index (FI) were calculated, the linear anatomic parameters of the skull and mandible were measured, the location of the mandibular foramen was identified, and the shapes of the skulls and mandibles were determined. Quantitative statistical data were obtained based on the location of the mandibular foramen, considering different shapes of skulls and faces. Results: there is a significant correlation between the location of the mandibular foramen, the high lengthy index (HLI) of the mandible, and the longitudinal latitude index (LLI) of the mandibular process. Conclusions: personalized assessment of the mandibular foramen based on a comprehensive analysis of craniometric characteristics can contribute to preventing unwanted dental and surgical complications, such as inferior alveolar nerve damage.

Objective: The aim of the study was to evaluate the dynamics of skin temperature at the injection points of botulinum toxin type A in the forehead area at different time stages as a marker of the vasomotor response and restoration of microcirculation after aesthetic botulinum therapy. Methods: The prospective study included 126 patients (19–59 years old, mean age 34.4 ± 1.2 years) who underwent injections of botulinum toxin type A at standard points of m. frontalis, m. procerus, and m. corrugator supercilii. Skin temperature was recorded with an infrared thermal imager at nine standardized points (P1–P9) at the following stages: before the procedure (T0), immediately after (T1), after 30 min (T2), after 14 (T14) and 30 (T30) days. The analysis was performed using analysis of variance with repeated measures and post hoc tests (p < 0.05). Results: A typical three-phase pattern of temperature response was revealed: an immediate decrease in temperature at all points immediately after injections (T1, −1.7–4.8% relative to the baseline, p < 0.001), subsequent reactive hyperemia after 30 min (T2, an increase of 2.35–5.8% at points P1, P2, P4–P7) and normalization of indicators by T14–T30. The most pronounced and stable changes were recorded at the interbrow points P7–P9, projecting to m. corrugator supercilii and m. procerus, which reflects their higher functional and vascular activity. Conclusions: Infrared thermography allows for objective recording of the phasic vasomotor response of the skin to injections of botulinum toxin type A, can be used to assess individual vascular response, and may aid in individualized treatment planning for aesthetic botulinum therapy.