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Dr. Nadia Musco
University of Napoli Federico II Department of Veterinary Medicine and Animal Production

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0 Animal Nutrition
0 Ruminant Nutrition
0 Milk quality
0 dietary fiber
0 Milk Fatty Acid

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Animal Nutrition
Milk quality
Ruminant Nutrition
Milk Fatty Acid

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Short Biography

Nadia Musco graduated in Animal Science (2010) at the University of Naples Federico II and achieved a PhD in "Production and health of food of animal origin" (2014). Since 2019, she has been a Researcher in Animal Nutrition and Feeding (SSD AGR/18) at the Department of Veterinary Medicine and Animal Production, University of Naples Federico II. Her research activity consists of 44 publications in indexed journals, often characterized by scientific collaborations with national and international research groups.

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Correspondence
Published: 22 June 2021 in Journal of Comparative Pathology
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ACS Style

Flavia Carriero; Angela Giovazzino; Valentina Rubino; Giuseppina Ruggiero; Anna Teresa Palatucci; Giuseppe Terrazzano; Laura Cortese; Pietro Lombardi; Nadia Musco; Diego Piantedosi. An Open Question in the COVID-19 Pandemic: Can Humans Transmit the Disease to Pets and Vice Versa? Journal of Comparative Pathology 2021, 1 .

AMA Style

Flavia Carriero, Angela Giovazzino, Valentina Rubino, Giuseppina Ruggiero, Anna Teresa Palatucci, Giuseppe Terrazzano, Laura Cortese, Pietro Lombardi, Nadia Musco, Diego Piantedosi. An Open Question in the COVID-19 Pandemic: Can Humans Transmit the Disease to Pets and Vice Versa? Journal of Comparative Pathology. 2021; ():1.

Chicago/Turabian Style

Flavia Carriero; Angela Giovazzino; Valentina Rubino; Giuseppina Ruggiero; Anna Teresa Palatucci; Giuseppe Terrazzano; Laura Cortese; Pietro Lombardi; Nadia Musco; Diego Piantedosi. 2021. "An Open Question in the COVID-19 Pandemic: Can Humans Transmit the Disease to Pets and Vice Versa?" Journal of Comparative Pathology , no. : 1.

Journal article
Published: 08 June 2021 in Sustainability
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The effects of replacement of maize grain with ancient wheat by-products on intestinal morphometry and enzymatic activity in laying hens was studied. Eighty hens were divided into two groups (40 each, 8 replicates, 5 hens/replicate) fed two isoproteic and isoenergetic diets. In the treated group, part of the maize was replaced by a mix of ancient grains (AGs) middling, in a 50:50 ratio of Triticum aestivum L. var. spelta (spelt) and Triticum durum dicoccum L. (emmer wheat). The AG diet affected the weight of all the large intestine tracts, decreasing the weight of caeca (p< 0.01) and increasing those of colon (p< 0.01), rectum and cloaca (p< 0.05). Villus height in the AG group was higher (p< 0.01) than the control for the duodenum and jejunum, while for the ileum, the control group showed the highest values (p< 0.01). The submucosa thickness was higher (p< 0.01) in the control group for the duodenum and ileum, while the jejunum for the AG group showed the highest (p< 0.05) submucosa thickness. The crypts depth was higher (p< 0.01) in the control group for the duodenum and ileum. Enzyme activity was enhanced by AGs (p< 0.01) in the duodenum. Regarding the jejunum, sucrase-isomaltase and alkaline phosphatase had higher activity (p< 0.05 and p< 0.01, respectively) in the AG group. In the ileum, sucrase-isomaltase showed higher activity (p< 0.01) in the control group, while alkaline phosphatase showed the highest values (p< 0.05) in the AG group. Overall, results suggested that the dietary inclusion of AGs exerted positive effects in hens, showing an improved intestinal function.

ACS Style

Nicola Addeo; Basilio Randazzo; Ike Olivotto; Maria Messina; Francesca Tulli; Nadia Musco; Giovanni Piccolo; Antonino Nizza; Carmelo Di Meo; Fulvia Bovera. Replacing Maize Grain with Ancient Wheat Lines By-Products in Organic Laying Hens’ Diet Affects Intestinal Morphology and Enzymatic Activity. Sustainability 2021, 13, 6554 .

AMA Style

Nicola Addeo, Basilio Randazzo, Ike Olivotto, Maria Messina, Francesca Tulli, Nadia Musco, Giovanni Piccolo, Antonino Nizza, Carmelo Di Meo, Fulvia Bovera. Replacing Maize Grain with Ancient Wheat Lines By-Products in Organic Laying Hens’ Diet Affects Intestinal Morphology and Enzymatic Activity. Sustainability. 2021; 13 (12):6554.

Chicago/Turabian Style

Nicola Addeo; Basilio Randazzo; Ike Olivotto; Maria Messina; Francesca Tulli; Nadia Musco; Giovanni Piccolo; Antonino Nizza; Carmelo Di Meo; Fulvia Bovera. 2021. "Replacing Maize Grain with Ancient Wheat Lines By-Products in Organic Laying Hens’ Diet Affects Intestinal Morphology and Enzymatic Activity." Sustainability 13, no. 12: 6554.

Journal article
Published: 29 May 2021 in Biomolecules
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The use of seaweeds as additives in animal nutrition may be a valid option to traditional feed as they represent a rich source of minerals, carbohydrates and antioxidants. The aim of this study was to analyze the chemical composition and in vitro antioxidant capacity of two tropical eucheumatoids, Kappaphycus alvarezii and Kappaphycus striatus, in Malaysian wild offshore waters. The chemical analysis was performed via inductively coupled plasma–optical emission spectroscopy for evaluating the concentration of toxic (Cd, Pb, Hg, As) and essential elements (Mn, Fe, Cu, Ni, Zn, Se); NMR spectroscopy was used for carrageenans investigation. Furthermore, the soluble and fat-soluble antioxidant capacities were determined by FRAP, DPPH and ABTS assays. The chemical analysis revealed a higher content of trace elements in K. alvarezii as compared to K. striatus, and both exhibited a high mineral content. No significant differences in metal concentrations were found between the two species. Both samples showed a mixture of prevailing κ- and t-carrageenans. Finally, the levels of soluble and fat-soluble antioxidants in K. alvarezii were significantly higher than in K. striatus. Our findings suggest that K. alvarezii could be used as a potential feed additive because of its favorable chemical and nutritional features.

ACS Style

Andrea Ariano; Nadia Musco; Lorella Severino; Anna De Maio; Annabella Tramice; Giuseppina Tommonaro; Sara Damiano; Angelo Genovese; Oladokun Olanrewaju; Fulvia Bovera; Giulia Guerriero. Chemistry of Tropical Eucheumatoids: Potential for Food and Feed Applications. Biomolecules 2021, 11, 804 .

AMA Style

Andrea Ariano, Nadia Musco, Lorella Severino, Anna De Maio, Annabella Tramice, Giuseppina Tommonaro, Sara Damiano, Angelo Genovese, Oladokun Olanrewaju, Fulvia Bovera, Giulia Guerriero. Chemistry of Tropical Eucheumatoids: Potential for Food and Feed Applications. Biomolecules. 2021; 11 (6):804.

Chicago/Turabian Style

Andrea Ariano; Nadia Musco; Lorella Severino; Anna De Maio; Annabella Tramice; Giuseppina Tommonaro; Sara Damiano; Angelo Genovese; Oladokun Olanrewaju; Fulvia Bovera; Giulia Guerriero. 2021. "Chemistry of Tropical Eucheumatoids: Potential for Food and Feed Applications." Biomolecules 11, no. 6: 804.

Journal article
Published: 28 May 2021 in Small Ruminant Research
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A phytocomplex composed by Schizochytrium limacinum, a species of marine alga, Galega officinalis, an herbaceous plant of the Faboideae subfamily, and linseeds, was administered to lactating grazing goats in order to evaluate its effects on milk yield and quality, and to investigate possible effects on goat health status. The hypothesis was that, by using a phytocomplex including plants known to exert an improvement of milk yield and milk quality, a synergism should be possible in order to obtain such effects using low doses, thus avoiding adverse effects. Milk fat was significantly (p<0.05) higher in treated group (4.02 vs. 3.61 %), in particular, levels of MUFA (24.55 vs 22.56 %), total n3 (1.34 vs 1.19 %) and total CLAs (0.52 vs. 0.40 %), were increased while n6/n3 (1.71 vs. 2.21 %) ratio was decreased. Concerning biochemical parameters, a significant (p<0.05) decrease of creatinine (0.73 vs. 0.84 mg/dl) was observed in treated animals, but the levels fell within the normal range for this species. Thus, the addition of the proposed phytocomplex to the diet of grazing goats may be successfully used to improve milk fatty acids profile without negative effects on animal health.

ACS Style

Vincenzo Mastellone; Valeria Maria Morittu; Nadia Musco; Anna Antonella Spina; Andrea Malgeri; Maria Luce Molinari; Biagio D’Aniello; Federico Infascelli; Raffaella Tudisco; Pietro Lombardi. Dietary supplementation with a phytocomplex affects blood parameters and milk yield and quality in grazing goats. Small Ruminant Research 2021, 201, 106421 .

AMA Style

Vincenzo Mastellone, Valeria Maria Morittu, Nadia Musco, Anna Antonella Spina, Andrea Malgeri, Maria Luce Molinari, Biagio D’Aniello, Federico Infascelli, Raffaella Tudisco, Pietro Lombardi. Dietary supplementation with a phytocomplex affects blood parameters and milk yield and quality in grazing goats. Small Ruminant Research. 2021; 201 ():106421.

Chicago/Turabian Style

Vincenzo Mastellone; Valeria Maria Morittu; Nadia Musco; Anna Antonella Spina; Andrea Malgeri; Maria Luce Molinari; Biagio D’Aniello; Federico Infascelli; Raffaella Tudisco; Pietro Lombardi. 2021. "Dietary supplementation with a phytocomplex affects blood parameters and milk yield and quality in grazing goats." Small Ruminant Research 201, no. : 106421.

Review
Published: 28 March 2021 in Nutrients
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Milk contains several important nutrients that are beneficial for human health. This review considers the nutritional qualities of essential fatty acids (FAs), especially omega-3 (ω-3) and omega-6 (ω-6) polyunsaturated fatty acids (PUFAs) present in milk from ruminant and non-ruminant species. In particular, the impact of milk fatty acids on metabolism is discussed, including its effects on the central nervous system. In addition, we presented data indicating how animal feeding—the main way to modify milk fat composition—may have a potential impact on human health, and how rearing and feeding systems strongly affect milk quality within the same animal species. Finally, we have presented the results of in vivo studies aimed at supporting the beneficial effects of milk FA intake in animal models, and the factors limiting their transferability to humans were discussed.

ACS Style

Maria Mollica; Giovanna Trinchese; Fabiano Cimmino; Eduardo Penna; Gina Cavaliere; Raffaella Tudisco; Nadia Musco; Claudia Manca; Angela Catapano; Marcellino Monda; Paolo Bergamo; Sebastiano Banni; Federico Infascelli; Pietro Lombardi; Marianna Crispino. Milk Fatty Acid Profiles in Different Animal Species: Focus on the Potential Effect of Selected PUFAs on Metabolism and Brain Functions. Nutrients 2021, 13, 1111 .

AMA Style

Maria Mollica, Giovanna Trinchese, Fabiano Cimmino, Eduardo Penna, Gina Cavaliere, Raffaella Tudisco, Nadia Musco, Claudia Manca, Angela Catapano, Marcellino Monda, Paolo Bergamo, Sebastiano Banni, Federico Infascelli, Pietro Lombardi, Marianna Crispino. Milk Fatty Acid Profiles in Different Animal Species: Focus on the Potential Effect of Selected PUFAs on Metabolism and Brain Functions. Nutrients. 2021; 13 (4):1111.

Chicago/Turabian Style

Maria Mollica; Giovanna Trinchese; Fabiano Cimmino; Eduardo Penna; Gina Cavaliere; Raffaella Tudisco; Nadia Musco; Claudia Manca; Angela Catapano; Marcellino Monda; Paolo Bergamo; Sebastiano Banni; Federico Infascelli; Pietro Lombardi; Marianna Crispino. 2021. "Milk Fatty Acid Profiles in Different Animal Species: Focus on the Potential Effect of Selected PUFAs on Metabolism and Brain Functions." Nutrients 13, no. 4: 1111.

Journal article
Published: 13 January 2021 in Animals
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The study aimed to compare two diets, Control (CTR) and Experimental (EX) (mainly differing as regards their ingredients, energy, and protein contents) administered to medium and large-sized bitches from two months before the expected proestrus and up to 30 days after delivery on mothers’ weight, body condition score, litter size, milk quality, and puppies’ growth. No differences were found for body weight during pregnancy, even if the BCS after delivery was significantly (p < 0.01) higher in the EX group than in the CTR one. Concerning the size effect, the percentage of weight gain on the initial body weight was double in medium-sized dogs compared to large dogs (p < 0.01). The number of puppies per litter was significantly higher (p < 0.05) for the EX group compared to the CTR one. Concerning puppies’ weight, the CTR group showed a significantly (p < 0.01) higher body weight from the 21st day of life due to the significant (p < 0.01) higher daily weight gain during the suckling period. Considering the performance of bitches and puppies, both diets seem useful for these stages of their lives. In fact, after 30 days of lactation, all tested bitches showed a healthy status and both the percentage of newborns mortality and puppies’ growth kinetics fell into the normal physiological range for the species.

ACS Style

Serena Calabrò; Alessandro Vastolo; Nadia Musco; Pietro Lombardi; Alessandro Troisi; Angela Polisca; Emanuela Vallesi; Riccardo Orlandi; Monica I. Cutrignelli. Effects of Two Commercial Diets on Several Reproductive Parameters in Bitches: Note Two—Lactation and Puppies’ Performance. Animals 2021, 11, 173 .

AMA Style

Serena Calabrò, Alessandro Vastolo, Nadia Musco, Pietro Lombardi, Alessandro Troisi, Angela Polisca, Emanuela Vallesi, Riccardo Orlandi, Monica I. Cutrignelli. Effects of Two Commercial Diets on Several Reproductive Parameters in Bitches: Note Two—Lactation and Puppies’ Performance. Animals. 2021; 11 (1):173.

Chicago/Turabian Style

Serena Calabrò; Alessandro Vastolo; Nadia Musco; Pietro Lombardi; Alessandro Troisi; Angela Polisca; Emanuela Vallesi; Riccardo Orlandi; Monica I. Cutrignelli. 2021. "Effects of Two Commercial Diets on Several Reproductive Parameters in Bitches: Note Two—Lactation and Puppies’ Performance." Animals 11, no. 1: 173.

Journal article
Published: 12 January 2021 in Agriculture
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The influence of replacing silage with sorghum silage in the diet of dairy buffalo cows on metabolic status and on milk yield, chemical characteristics, and fatty acid profile was studied. Forty dairy buffalo cows were included in the trial and divided into two homogeneous groups (SS, sorghum silage and CS, corn silage). Blood was collected at the end of the trial (120 days), individual milk yield was registered daily. Samples of milk were monthly collected and analyzed for fat, protein, and lactose. Moreover, fatty acid profiles of silages and milk were determined. Buffalo cows fed sorghum silage showed an average milk yield higher than group CS (kg/d 10.120 vs. 9.270; p < 0.05), probably due to the lower lignin content of sorghum silage (31.0 g/kg dry matter (DM)) compared to corn silage (47.0 g/kg DM) and, by consequence, to the higher digestibility of SS diet. The percentage of linoleic acid was significantly higher in milk of group CS (C18:2: 1.27 vs. 2.05%; p < 0.01) due to the higher content of these acids in corn than in sorghum silage. The omega 6/omega 3 ratio was significantly lower in milk from buffalo cows fed sorghum than those fed corn silage (7.8 vs. 12.9; p < 0.01). Serum biochemistry showed no negative effects of the corn replacing with sorghum.

ACS Style

Raffaella Tudisco; Valeria Morittu; Nadia Musco; Micaela Grossi; Piera Iommelli; Biagio D’Aniello; Maria Ferrara; Federico Infascelli; Pietro Lombardi. Effects of Sorghum Silage in Lactating Buffalo Cow Diet: Biochemical Profile, Milk Yield, and Quality. Agriculture 2021, 11, 57 .

AMA Style

Raffaella Tudisco, Valeria Morittu, Nadia Musco, Micaela Grossi, Piera Iommelli, Biagio D’Aniello, Maria Ferrara, Federico Infascelli, Pietro Lombardi. Effects of Sorghum Silage in Lactating Buffalo Cow Diet: Biochemical Profile, Milk Yield, and Quality. Agriculture. 2021; 11 (1):57.

Chicago/Turabian Style

Raffaella Tudisco; Valeria Morittu; Nadia Musco; Micaela Grossi; Piera Iommelli; Biagio D’Aniello; Maria Ferrara; Federico Infascelli; Pietro Lombardi. 2021. "Effects of Sorghum Silage in Lactating Buffalo Cow Diet: Biochemical Profile, Milk Yield, and Quality." Agriculture 11, no. 1: 57.

Journal article
Published: 25 December 2020 in Animals
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The close link between nutrition management and reproductive efficiency is well known, but there is very little data available concerning this topic in canine species. The present study aimed to compare the effect of two different diets upon the follicular period and gestation in bitches. Eighteen pluriparus medium and large size bitches were recruited and divided into control (CTR) and experimental (EX) groups and fed, respectively, with a commercial kibble diet and a specially formulated diet from two months before the expected onset of proestrus up to the end of the trial. It was possible to observe how the EX group had a better clinical presentation of the estrous phase, a higher number of ovarian follicles (p < 0.05), a lower percentage of fetal resorption (p < 0.05), and lower oxidative status, expressed by d-ROMs (p < 0.01), at the moment of pregnancy diagnosis compared to CTR group. Moreover, the EX group showed a lower fetal resorption rate and higher litter size (p < 0.05). These results highlight how a diet characterized by high protein and fat content and richer in essential fatty acids can improve reproductive performance in dogs.

ACS Style

Riccardo Orlandi; Emanuela Vallesi; Serena Calabrò; Alessandro Vastolo; Nadia Musco; Alessandro Troisi; Angela Polisca; Pietro Lombardi; Monica I. Cutrignelli. Effects of Two Commercial Diets on Several Reproductive Parameters in Bitches: Note One—From Estrous Cycle to Parturition. Animals 2020, 11, 23 .

AMA Style

Riccardo Orlandi, Emanuela Vallesi, Serena Calabrò, Alessandro Vastolo, Nadia Musco, Alessandro Troisi, Angela Polisca, Pietro Lombardi, Monica I. Cutrignelli. Effects of Two Commercial Diets on Several Reproductive Parameters in Bitches: Note One—From Estrous Cycle to Parturition. Animals. 2020; 11 (1):23.

Chicago/Turabian Style

Riccardo Orlandi; Emanuela Vallesi; Serena Calabrò; Alessandro Vastolo; Nadia Musco; Alessandro Troisi; Angela Polisca; Pietro Lombardi; Monica I. Cutrignelli. 2020. "Effects of Two Commercial Diets on Several Reproductive Parameters in Bitches: Note One—From Estrous Cycle to Parturition." Animals 11, no. 1: 23.

Preprint
Published: 25 November 2020
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The influence of replacing corn silage with sorghum silage in the diet of dairy buffalo cows on metabolic status and on milk yield, chemical characteristics and fatty acid profile was studied. Forty dairy buffalo cows were included in the trial and divided into two homogeneous groups (SS, sorghum and CC, corn). Blood was collected at the end of the trial (120 days), individual milk yield was registered daily. Samples of milk were monthly collected and analyzed for fat, protein and lactose. Moreover, fatty acid profiles of silages and milk were determined. Buffalo cows fed sorghum silage showed an average milk yield higher than group CS (kg/d 10.120 vs 9.270; P<0.05), probably due to the lower lignin content of sorghum silage (31 vs 47 g/kg dry matter, respectively for SS and CS diets) and by consequence to its energy value, higher than expected. The percentage of linoleic acid was significantly higher in milk of group CS (C18:2: 1.27% vs 2.05%; P<0.01) due to the higher content of these acids in corn than in sorghum silage. The omega 6/omega 3 ratio was significantly lower in milk from buffalo cows fed sorghum than corn silage (7.8 vs 12.9; P<0.01). Serum biochemistry showed no negative effects of the corn replacing with sorghum.

ACS Style

Raffaella Tudisco; Valeria Maria Morittu; Nadia Musco; Micaela Grossi; Piera Iommelli; Biagio D' Aniello; Maria Ferrara; Pietro Lombardi; Federico Infascelli. Effects of Sorghum Silage in Lactating Buffalo Cow Diet: Biochemical Profile, Milk Yield and Quality. 2020, 1 .

AMA Style

Raffaella Tudisco, Valeria Maria Morittu, Nadia Musco, Micaela Grossi, Piera Iommelli, Biagio D' Aniello, Maria Ferrara, Pietro Lombardi, Federico Infascelli. Effects of Sorghum Silage in Lactating Buffalo Cow Diet: Biochemical Profile, Milk Yield and Quality. . 2020; ():1.

Chicago/Turabian Style

Raffaella Tudisco; Valeria Maria Morittu; Nadia Musco; Micaela Grossi; Piera Iommelli; Biagio D' Aniello; Maria Ferrara; Pietro Lombardi; Federico Infascelli. 2020. "Effects of Sorghum Silage in Lactating Buffalo Cow Diet: Biochemical Profile, Milk Yield and Quality." , no. : 1.

Journal article
Published: 30 September 2020 in Research in Veterinary Science
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The aim of this research was to evaluate the effects of the partial substitution of maize grain with local ancient wheats by-products in an organic laying hens farm on animal performance and blood profile, as well as on eggs quality. A total of 80 Hy-Line W-36 Single Comb White Leghorn, 18 weeks old hens were homogenously divided into two groups. The two groups (40 laying hens each, 8 replicates, 5 hens/replicate) were fed two isoprotein and isoenergetic diets: the Control group (C) was fed a standard, organic maize-soybean meal diet whereas in the Ancient Grains group (AG) part of the maize grain was replaced by a mix of ancient grains middling, consisting in 50:50 of Triticum aestivum var. spelta (spelt) and Triticum durum dicoccum L. (emmer wheat). The birds fed the maize based-diet (C) showed a higher (P < 0.01) egg weight and feed intake than the Ancient Grains (AG) group. By contrary, the feed conversion ratio was more favourable (P < 0.05) in hens fed the Ancient Grains diet. The eggs produced by the hens fed the Control diet showed higher length and width than the other group (P < 0.01). The shell thickness and strength were also higher in the Control group (P < 0.01 and P < 0.05, respectively). The experimental dietary treatment positively affected some blood parameters. The Control group showed higher levels of cholesterol and triglycerides (P < 0.05) as well as of alanine aminotransferase (ALT) and gamma-glutamyl transferase (GGT) (P < 0.01). In addition, butyrate, which may have great implications for the regulation of the immune response, resulted significantly higher in the caecal content of hens from the Ancient Grains group. Overall, the Ancient Grains diet seemed to be able to guarantee the production performances with positive effects on the animal health.

ACS Style

Pietro Lombardi; Nicola F. Addeo; Valentina Panettieri; Nadia Musco; Giovanni Piccolo; Giuseppe Vassalotti; Antonino Nizza; Giuseppe Moniello; Fulvia Bovera. Blood profile and productive performance after partial substitution of maize grain with ancient wheat lines by-products in organic laying hens' diet. Research in Veterinary Science 2020, 133, 232 -238.

AMA Style

Pietro Lombardi, Nicola F. Addeo, Valentina Panettieri, Nadia Musco, Giovanni Piccolo, Giuseppe Vassalotti, Antonino Nizza, Giuseppe Moniello, Fulvia Bovera. Blood profile and productive performance after partial substitution of maize grain with ancient wheat lines by-products in organic laying hens' diet. Research in Veterinary Science. 2020; 133 ():232-238.

Chicago/Turabian Style

Pietro Lombardi; Nicola F. Addeo; Valentina Panettieri; Nadia Musco; Giovanni Piccolo; Giuseppe Vassalotti; Antonino Nizza; Giuseppe Moniello; Fulvia Bovera. 2020. "Blood profile and productive performance after partial substitution of maize grain with ancient wheat lines by-products in organic laying hens' diet." Research in Veterinary Science 133, no. : 232-238.

Journal article
Published: 29 May 2020 in Animals
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The possibility to associate nutraceuticals, as immune-modulating tools, to the treatment of visceral leishmaniosis is a matter of great interest. In this study, we investigated whether the administration of a nutritional supplement (DìLshTM, Dynamopet SRL, Verona, Italy) was able to exert beneficial effects on the inflammatory state and oxidative stress of the dogs naturally infected by Leishmania infantum. To this purpose, specific parameters, namely Tumor Necrosis Factor -alpha (TNFα), Interleukin-6 (IL-6), Inteleukin-10 (IL-10), leptin, derivates of Reactive Oxigen Metabolites (d-Roms) and Biological Antioxidant Potential (BAP), as well as the haematological and biochemical profiles of the infected dogs, were investigated upon the treatment with the nutritional supplement and compared with the conventional pharmacological anti-Leishmania therapy. The animals underwent complete clinical examination and blood sample collection before (T0) and 3 months after (T90) the onset of the two treatments. The two treatments showed similar results: significant clinical improvement, ELISA positivity and IgG decrease, an increase in IL-10, and a decrease in IL-6 were observed in animals treated with the nutritional supplement. A decrease in d-Roms and an increase in BAP were also detected in both groups. On the whole, the nutritional supplement possesses anti-inflammatory and antioxidant properties, suggesting that it may support animals’ health and be useful to extend the time a drug therapy is needed.

ACS Style

Vincenzo Mastellone; Nadia Musco; Giuseppe Vassalotti; Diego Piantedosi; Alessandro Vastolo; Monica Isabella Cutrignelli; Domenico Britti; Laura Cortese; Pietro Lombardi. A Nutritional Supplement (DìLshTM) Improves the Inflammatory Cytokines Response, Oxidative Stress Markers and Clinical Signs in Dogs Naturally Infected by Leishmania infantum. Animals 2020, 10, 938 .

AMA Style

Vincenzo Mastellone, Nadia Musco, Giuseppe Vassalotti, Diego Piantedosi, Alessandro Vastolo, Monica Isabella Cutrignelli, Domenico Britti, Laura Cortese, Pietro Lombardi. A Nutritional Supplement (DìLshTM) Improves the Inflammatory Cytokines Response, Oxidative Stress Markers and Clinical Signs in Dogs Naturally Infected by Leishmania infantum. Animals. 2020; 10 (6):938.

Chicago/Turabian Style

Vincenzo Mastellone; Nadia Musco; Giuseppe Vassalotti; Diego Piantedosi; Alessandro Vastolo; Monica Isabella Cutrignelli; Domenico Britti; Laura Cortese; Pietro Lombardi. 2020. "A Nutritional Supplement (DìLshTM) Improves the Inflammatory Cytokines Response, Oxidative Stress Markers and Clinical Signs in Dogs Naturally Infected by Leishmania infantum." Animals 10, no. 6: 938.

Journal article
Published: 28 February 2020 in Animals
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The demand of vegetable protein is currently very high, both for human and animal nutrition. Soybean meal is the most used protein source in ruminant nutrition. Many Leguminosae seeds (i.e., faba bean, lupin, proteic pea), rich in protein and energy, are considered a valid alternative, especially in the organic production system. In this paper the physical and nutritional characteristics of eight varieties of Vicia Faba bean (four local and four commercial) were evaluated. To evaluate the digestive utilization an in vitro trial was carried out, incubating each substrate with an inoculum made up of bovine buffered rumen liquor for 48 h at 39 °C under anaerobiosis. The gas produced within the incubation period was registered, the dry matter digestibility and volatile fatty acid at the end of fermentation were determined. The results of this investigation confirm the possibility of using local faba bean varieties in ruminant nutrition with the advantages that, being local natural resources, they are better adapted to the climate and agronomic conditions and limit the environmental impact. Faba bean is an important vegetable protein source for ruminant diets. This research aimed to compare the nutritional characteristics of four commercial and four local cultivars in order to better characterise the local ones and promote their use in animal nutrition. The seeds’ weight and the chemical composition, including starch and the energy, was evaluated. The in vitro fermentation characteristics were studied for 48 h using bull’s rumen fluid as inoculum. All the varieties showed the values’ weight corresponding to the specific botanical typology. The varieties significantly differed for protein, starch and lignin (p < 0.01) and structural carbohydrates (p < 0.05) concentration. No significant differences were observed for energy content. All the in vitro fermentation parameters resulted significantly different among the varieties. Organic matter degradability ranged between 89.9% and 85.1% and the potential gas production from 367 to 325 mL/g. The Pearson’s analysis showed significant correlation between morphological characteristics, chemical data and in vitro fermentation parameters. In conclusion, this investigation confirms the possibility of using local faba bean varieties (i.e., Aquino, Castrocielo, 13#5, 4#4) in ruminant nutrition with the advantage that, being local natural resources, they are better adapted to the climate and agronomic conditions and limit environmental impact.

ACS Style

Alessandra Pelagalli; Nadia Musco; Nikita Trotta; Monica I. Cutrignelli; Antonio Di Francia; Federico Infascelli; Raffaella Tudisco; Pietro Lombardi; Alessandro Vastolo; Serena Calabrò. Chemical Characterisation and in Vitro Gas Production Kinetics of Eight Faba Bean Varieties. Animals 2020, 10, 398 .

AMA Style

Alessandra Pelagalli, Nadia Musco, Nikita Trotta, Monica I. Cutrignelli, Antonio Di Francia, Federico Infascelli, Raffaella Tudisco, Pietro Lombardi, Alessandro Vastolo, Serena Calabrò. Chemical Characterisation and in Vitro Gas Production Kinetics of Eight Faba Bean Varieties. Animals. 2020; 10 (3):398.

Chicago/Turabian Style

Alessandra Pelagalli; Nadia Musco; Nikita Trotta; Monica I. Cutrignelli; Antonio Di Francia; Federico Infascelli; Raffaella Tudisco; Pietro Lombardi; Alessandro Vastolo; Serena Calabrò. 2020. "Chemical Characterisation and in Vitro Gas Production Kinetics of Eight Faba Bean Varieties." Animals 10, no. 3: 398.

Journal article
Published: 24 February 2020 in Foods
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A clarification method was proposed to ameliorate the technological quality of fruit juices by preserving bioactive compounds. This study evaluated the in vitro antioxidant and hypoglycemic activities and the in vivo effects of Punica granatum L. natural (NJ) and clarified (CJ) juice by polyvinylidene fluoride (PVDF) hollow fiber membrane. CJ was more active as an antioxidant and as a α-glucosidase inhibitor than NJ. Mice were orally gavaged with water (Control), NJ, and CJ for 28 days. NJ group showed significant decrease of alanine aminotransferase, aspartate amino transferase, and creatine-phosphokinase. CJ administration was associated with urea, creatine-phosphokinase, and triglycerides values significantly lower with respect to the control. Oxidative status was ameliorated with CJ administration, showing a reactive oxygen metabolites (d-ROMs) reduction of 32% and a biological antioxidant potential (BAP) boosting of 23% compared to the control, whereas NJ did not show a similar effect. Results confirmed the beneficial properties of pomegranate juice, showing that membrane clarification may enhance such effects in terms of antioxidant activity.

ACS Style

Valeria Maria Morittu; Vincenzo Mastellone; Rosa Tundis; Monica Rosa Loizzo; Raffaella Tudisco; Alberto Figoli; Alfredo Cassano; Nadia Musco; Domenico Britti; Federico Infascelli; Pietro Lombardi. Antioxidant, Biochemical, and In-Life Effects of Punica granatum L. Natural Juice vs. Clarified Juice by Polyvinylidene Fluoride Membrane. Foods 2020, 9, 242 .

AMA Style

Valeria Maria Morittu, Vincenzo Mastellone, Rosa Tundis, Monica Rosa Loizzo, Raffaella Tudisco, Alberto Figoli, Alfredo Cassano, Nadia Musco, Domenico Britti, Federico Infascelli, Pietro Lombardi. Antioxidant, Biochemical, and In-Life Effects of Punica granatum L. Natural Juice vs. Clarified Juice by Polyvinylidene Fluoride Membrane. Foods. 2020; 9 (2):242.

Chicago/Turabian Style

Valeria Maria Morittu; Vincenzo Mastellone; Rosa Tundis; Monica Rosa Loizzo; Raffaella Tudisco; Alberto Figoli; Alfredo Cassano; Nadia Musco; Domenico Britti; Federico Infascelli; Pietro Lombardi. 2020. "Antioxidant, Biochemical, and In-Life Effects of Punica granatum L. Natural Juice vs. Clarified Juice by Polyvinylidene Fluoride Membrane." Foods 9, no. 2: 242.

Papers
Published: 24 January 2020 in Italian Journal of Animal Science
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Yeast cell wall are a source of prebiotics in animal nutrition, able to improve microbial function in the large intestine. The purpose of this paper was to compare the fermentability of six Saccharomyces cerevisiae (SC) cell wall obtained from three production processes (alcoholic, brewers and bakers). For each production process the two aliquots characterised by the highest the lowest carbohydrate levels were selected. In order to perform the in vitro trial, each SC substrate was incubated at 39 °C under anaerobic condition for 72 h, using cat faecal inoculum. The results showed that the production processes did not affect organic matter disappearance, while significantly (p < .01) influenced cumulative volume of gas which appeared the lowest for alcoholic substrates. The alcoholic SC substrate showed significantly highest (p < .01) fermentation rate. All SCFA were affected by the production processes (p < .01). In particular, brewers substrates showed the highest acetate and butyrate production, while the fermentation of SC cell wall obtained by bakers showed the highest production of valerate, iso-butyrate and iso-valerate. Considering the high fermentability and acetate and butyrate production, the SC cell wall obtained by brewers seem more suitable to be used as prebiotic in cat diet. The bakers extract seems less advisable, due to its less fermentability at which corresponded the highest production of gas and iso-butyrate and iso-valerate, which are considered the less desirable end-products. The study underlines that it is necessary to evaluate the fermentation characteristics of these ingredients before their use in diet formulation as source of prebiotics.

ACS Style

Serena Calabrò; Nadia Musco; Fernando Roberti; Alessandro Vastolo; Mario Coppola; Luigi Esposito; Monica Isabella Cutrignelli. Fermentability characteristics of different Saccharomyces cerevisiae cell wall using cat faeces as inoculum. Italian Journal of Animal Science 2020, 19, 186 -193.

AMA Style

Serena Calabrò, Nadia Musco, Fernando Roberti, Alessandro Vastolo, Mario Coppola, Luigi Esposito, Monica Isabella Cutrignelli. Fermentability characteristics of different Saccharomyces cerevisiae cell wall using cat faeces as inoculum. Italian Journal of Animal Science. 2020; 19 (1):186-193.

Chicago/Turabian Style

Serena Calabrò; Nadia Musco; Fernando Roberti; Alessandro Vastolo; Mario Coppola; Luigi Esposito; Monica Isabella Cutrignelli. 2020. "Fermentability characteristics of different Saccharomyces cerevisiae cell wall using cat faeces as inoculum." Italian Journal of Animal Science 19, no. 1: 186-193.

Journal article
Published: 11 October 2019 in Animals
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The effects of linseed feeding on the stearoyl-CoA desaturase (SCD) activity were evaluated on grazing dairy goats divided into two homogeneous groups (C, control, and L, treated) fed the same amount of concentrate which, for group L was supplemented with linseed. Milk yield was unaffected by the treatment. Group L showed significantly higher milk fat (4.10% vs 2.94%, p < 0.01) than group S. Within milk fatty acids, group C showed significantly higher levels of saturated fatty acids and lower values of mono-unsaturated and polyunsaturated fatty acids. In group L, total CLAs were higher than in group S (0.646% vs 0.311%; p < 0.01) mainly because of the differences in CLA cis9 trans 11 (0.623% vs 0.304%; p < 0.01). In treated animals, SCD activity, measured as cis9 C14:1/C14:0, was lower than in the control group, mainly in July and August.

ACS Style

Raffaella Tudisco; Biagina Chiofalo; Vittorio Lo Presti; Valeria Maria Morittu; Giuseppe Moniello; Micaela Grossi; Nadia Musco; Raffaella Grazioli; Vincenzo Mastellone; Pietro Lombardi; Federico Infascelli. Influence of Feeding Linseed on SCD Activity in Grazing Goat Mammary Glands. Animals 2019, 9, 786 .

AMA Style

Raffaella Tudisco, Biagina Chiofalo, Vittorio Lo Presti, Valeria Maria Morittu, Giuseppe Moniello, Micaela Grossi, Nadia Musco, Raffaella Grazioli, Vincenzo Mastellone, Pietro Lombardi, Federico Infascelli. Influence of Feeding Linseed on SCD Activity in Grazing Goat Mammary Glands. Animals. 2019; 9 (10):786.

Chicago/Turabian Style

Raffaella Tudisco; Biagina Chiofalo; Vittorio Lo Presti; Valeria Maria Morittu; Giuseppe Moniello; Micaela Grossi; Nadia Musco; Raffaella Grazioli; Vincenzo Mastellone; Pietro Lombardi; Federico Infascelli. 2019. "Influence of Feeding Linseed on SCD Activity in Grazing Goat Mammary Glands." Animals 9, no. 10: 786.

Journal article
Published: 01 September 2019 in Animals
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The aim of this work was to propose a model of free-range raising for rabbit able to maximize the animal welfare and at the same time the productive performances through the use of mirrors. A total of 81 rabbits were allocated into free-range areas and divided into three groups (nine replicates per group): in the first group (face to face, F2F), the rabbits of each replicate could see each other. In the second group (blind) each replicate was isolated from the others; in the third group (mirrors), the replicates were divided as for the Blind group but two mirrors were placed in a corner of the perimeter. The blind group rabbits showed the lowest final weight (p < 0.05), while rabbits from the mirrors groups showed the best FCR and net dressing out values. The blind group showed the highest production of total short chain fatty acids, acetate (p < 0.05) and propionate (p < 0.01). The F2F rabbits showed higher levels of creatine phosphokinase and lactate dehydrogenase and lower values of blood glucose than those of the other groups, due to the higher locomotion activity. The use of mirrors can improve rabbit’s growth performance and carcass traits by lowering the rabbit’s locomotion activity in comparison to the other tested systems.

ACS Style

Nadia Musco; Pietro Lombardi; Nicola Francesco Addeo; Giulia Secci; Giuliana Parisi; Maria Elena Pero; Giovanni Piccolo; Antonino Nizza; Fulvia Bovera; Pero. Mirrors Can Affect Growth Rate, Blood Profile, Carcass and Meat Traits and Caecal Microbial Activity of Rabbits Reared in a “Small Group” Free-Range System. Animals 2019, 9, 639 .

AMA Style

Nadia Musco, Pietro Lombardi, Nicola Francesco Addeo, Giulia Secci, Giuliana Parisi, Maria Elena Pero, Giovanni Piccolo, Antonino Nizza, Fulvia Bovera, Pero. Mirrors Can Affect Growth Rate, Blood Profile, Carcass and Meat Traits and Caecal Microbial Activity of Rabbits Reared in a “Small Group” Free-Range System. Animals. 2019; 9 (9):639.

Chicago/Turabian Style

Nadia Musco; Pietro Lombardi; Nicola Francesco Addeo; Giulia Secci; Giuliana Parisi; Maria Elena Pero; Giovanni Piccolo; Antonino Nizza; Fulvia Bovera; Pero. 2019. "Mirrors Can Affect Growth Rate, Blood Profile, Carcass and Meat Traits and Caecal Microbial Activity of Rabbits Reared in a “Small Group” Free-Range System." Animals 9, no. 9: 639.

Journal article
Published: 26 August 2019 in Animals
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The effect of pasture on the stearoyl-CoA desaturase (SCD) and miRNA 103 expression was evaluated on dairy goats divided into two homogeneous groups (G, grazing, and S, stable). Group S was housed in a stall and received alfalfa hay as forage, while group G was led to pasture. The goats of both the groups received the same amount of concentrate. Milk yield did not differ statistically between the groups. Group G showed significantly higher fat (4.10% vs. 2.94%, p < 0.01) and protein percentage (3.43% vs. 3.25%; p < 0.05) than group S. Among milk fatty acids, group S showed significantly higher levels of saturated fatty acids (SFA) and lower values of mono-unsaturated fatty acid (MUFA). The percentages of polyunsaturated fatty acid (PUFA) were not different between groups even if pasture significantly affected the percentages of C18:3 and total omega 3. In group G, total CLAs were twice than in group S (0.646% vs. 0.311%; p < 0.01) mainly due to the differences in CLA cis9 trans 11 (0.623% vs. 0.304%; p < 0.01). Milk total CLA in grazing group was significantly (p < 0.01) higher in August according to the highest value of both linoleic and α-linolenic acids in the pasture. In grazing animals, SCD expression decreased from April to June, increased in July and decreased again in August, while it was almost unvaried along the trial in group S. By contrast, the expression of miRNA 103 showed a similar trend for both groups, decreasing from April to June, increasing in July and falling down in August. To our knowledge, this is the first observation of the effects of pasture on miRNA expression in milk from ruminant species.

ACS Style

Raffaella Tudisco; Valeria Maria Morittu; Laura Addi; Giuseppe Moniello; Micaela Grossi; Nadia Musco; Raffaella Grazioli; Vincenzo Mastellone; Maria Elena Pero; Pietro Lombardi; Federico Infascelli. Influence of Pasture on Stearoyl-CoA Desaturase and miRNA 103 Expression in Goat Milk: Preliminary Results. Animals 2019, 9, 606 .

AMA Style

Raffaella Tudisco, Valeria Maria Morittu, Laura Addi, Giuseppe Moniello, Micaela Grossi, Nadia Musco, Raffaella Grazioli, Vincenzo Mastellone, Maria Elena Pero, Pietro Lombardi, Federico Infascelli. Influence of Pasture on Stearoyl-CoA Desaturase and miRNA 103 Expression in Goat Milk: Preliminary Results. Animals. 2019; 9 (9):606.

Chicago/Turabian Style

Raffaella Tudisco; Valeria Maria Morittu; Laura Addi; Giuseppe Moniello; Micaela Grossi; Nadia Musco; Raffaella Grazioli; Vincenzo Mastellone; Maria Elena Pero; Pietro Lombardi; Federico Infascelli. 2019. "Influence of Pasture on Stearoyl-CoA Desaturase and miRNA 103 Expression in Goat Milk: Preliminary Results." Animals 9, no. 9: 606.

Journal article
Published: 14 August 2019 in Animals
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The purpose of the study is to determine the nutritional characteristics of some by-products derived from fruit juice and olive oil production to evaluate their use in pig nutrition. Five by-products of citrus fruit (three citrus fruit pulp and two molasses) and three by-products of olive oil (olive cake) obtained by different varieties are analysed for chemical composition. The fermentation characteristics are evaluated in vitro using the gas production technique with swine faecal inoculum. All the citrus by-products are highly fermentable, producing gas and a high amount of short-chain fatty acids. The fermentation kinetics vary when comparing pulps and molasses. Citrus fruit pulps show lower and slower fermentation rates than molasses. The olive oil by-products, compared to citrus fruits ones, are richer in NDF and ADL. These characteristics negatively affect all the fermentation parameters. Therefore, the high concentration of fiber and lipids represents a key aspect in the nutrition of fattening pigs. The preliminary results obtained in this study confirm that the use of by-products in pig nutrition could represent a valid opportunity the reduce the livestock economic cost and environmental impact.

ACS Style

Alessandro Vastolo; Serena Calabró; Luigi Liotta; Nadia Musco; Ambra Rita Di Rosa; Monica Isabella Cutrignelli; Biagina Chiofalo. In Vitro Fermentation and Chemical Characteristics of Mediterranean By-Products for Swine Nutrition. Animals 2019, 9, 556 .

AMA Style

Alessandro Vastolo, Serena Calabró, Luigi Liotta, Nadia Musco, Ambra Rita Di Rosa, Monica Isabella Cutrignelli, Biagina Chiofalo. In Vitro Fermentation and Chemical Characteristics of Mediterranean By-Products for Swine Nutrition. Animals. 2019; 9 (8):556.

Chicago/Turabian Style

Alessandro Vastolo; Serena Calabró; Luigi Liotta; Nadia Musco; Ambra Rita Di Rosa; Monica Isabella Cutrignelli; Biagina Chiofalo. 2019. "In Vitro Fermentation and Chemical Characteristics of Mediterranean By-Products for Swine Nutrition." Animals 9, no. 8: 556.

Journal article
Published: 06 August 2019 in Animals
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The aim of this research was to evaluate the possible usefulness of mirrors in improving rabbit behavior in a free-range breeding system. Three groups (each consisting of nine replicates of three animals) were compared: isolated, isolated with mirrors and separated by a wire mesh (possible visual and olfactory contacts). Rabbits allowed to have a visual and olfactory contact showed a significantly higher expression of important natural behaviors (olfactory investigation, gnawing, alertness, stretching, locomotion) compared to the isolated rabbits (with or without mirrors); while rabbits in the mirror group showed higher allo-grooming activity than those isolated and no different locomotion activity than those separated by wire mesh. Thus, mirrors seemed to be able to modify the behavioral repertoire of isolated rabbits by acting on social perception in rabbits reared in small groups in a free-range system. Nevertheless, despite it being advisable to use a combination of different indicators in order to assess the stress level of an animal, the accuracy of serum cortisol, as well as of some secondary stress markers assay, appeared to be limited in this type of breeding.

ACS Style

Vincenzo Mastellone; Fulvia Bovera; Nadia Musco; Valentina Panettieri; Giovanni Piccolo; Anna Scandurra; Carmelo Di Meo; Youssef A. Attia; Pietro Lombardi. Mirrors Improve Rabbit Natural Behavior in a Free-Range Breeding System. Animals 2019, 9, 533 .

AMA Style

Vincenzo Mastellone, Fulvia Bovera, Nadia Musco, Valentina Panettieri, Giovanni Piccolo, Anna Scandurra, Carmelo Di Meo, Youssef A. Attia, Pietro Lombardi. Mirrors Improve Rabbit Natural Behavior in a Free-Range Breeding System. Animals. 2019; 9 (8):533.

Chicago/Turabian Style

Vincenzo Mastellone; Fulvia Bovera; Nadia Musco; Valentina Panettieri; Giovanni Piccolo; Anna Scandurra; Carmelo Di Meo; Youssef A. Attia; Pietro Lombardi. 2019. "Mirrors Improve Rabbit Natural Behavior in a Free-Range Breeding System." Animals 9, no. 8: 533.

Journal article
Published: 30 July 2019 in Animals
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The use of nutraceuticals as immunomodulators in the treatment of visceral leishmaniasis has generated interest in the current approaches to treat the disease. In this clinical and immunological study, we investigated whether the administration of a nutritional supplement mediates the immune-modulatory response in canine leishmaniosis (CL) and improves the clinical outcome of the disease. With this purpose, we analysed T lymphocyte subsets in peripheral blood (PB) of 12 dogs naturally infected by Leishmania infantum, following treatment with a nutritional supplement. The regulatory T (Treg) cells and the T helper (Th) 1 population were specifically evaluated. The animals underwent complete clinical examination and blood sample collection for haematological, biochemical, serological and immunological analysis before treatment (T0), one month (T30) and 3 months (T90) after the onset of the nutraceutical supplementation. We observed that nutraceutical supplementation was associated with immunomodulation of Th1 response and significant clinical improvement of the animals. No side effects were observed. Therefore, a potential supportive role for the nutraceutical supplement during canine leishmaniasis is proposed.

ACS Style

Pietro Lombardi; Anna Teresa Palatucci; Angela Giovazzino; Vincenzo Mastellone; Giuseppina Ruggiero; Valentina Rubino; Nadia Musco; Rosalia Crupi; Monica Isabella Cutrignelli; Domenico Britti; Giuseppe Vassalotti; Giuseppe Terrazzano; Laura Cortese. Clinical and Immunological Response in Dogs Naturally Infected by L. infantum Treated with a Nutritional Supplement. Animals 2019, 9, 501 .

AMA Style

Pietro Lombardi, Anna Teresa Palatucci, Angela Giovazzino, Vincenzo Mastellone, Giuseppina Ruggiero, Valentina Rubino, Nadia Musco, Rosalia Crupi, Monica Isabella Cutrignelli, Domenico Britti, Giuseppe Vassalotti, Giuseppe Terrazzano, Laura Cortese. Clinical and Immunological Response in Dogs Naturally Infected by L. infantum Treated with a Nutritional Supplement. Animals. 2019; 9 (8):501.

Chicago/Turabian Style

Pietro Lombardi; Anna Teresa Palatucci; Angela Giovazzino; Vincenzo Mastellone; Giuseppina Ruggiero; Valentina Rubino; Nadia Musco; Rosalia Crupi; Monica Isabella Cutrignelli; Domenico Britti; Giuseppe Vassalotti; Giuseppe Terrazzano; Laura Cortese. 2019. "Clinical and Immunological Response in Dogs Naturally Infected by L. infantum Treated with a Nutritional Supplement." Animals 9, no. 8: 501.