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Sayuri Fuse is an appointed assistant professor at the Department of Sports Medicine for Health Promotion, Tokyo Medical University. She received her PhD degree in medicine from the Tokyo Medical University in 2017. Her research interests include exercise physiology and brown adipose tissue.
This study examined the relationship between plasma amino acid (AA) concentrations, including branched-chain AAs, and brown adipose tissue density (BAT-d). One hundred and seventy-three subjects (69 men, 104 women) aged 22–68 years were recruited during the winter season. AAs were comprehensively quantified using liquid chromatography-time-of-flight-mass spectrometry. The total hemoglobin concentration in the supraclavicular region ([total-Hb]sup), an indicator of BAT-d, was assessed using near-infrared time-resolved spectroscopy. Anthropometric parameters, including age, percentage of body fat, and visceral fat, were evaluated. Factors associated with higher (≥74 µM) or lower (<74 µM) [total-Hb]sup were investigated by multiple logistic regression models that included AA concentrations alone (model 1) or AA concentrations and anthropometric parameters (model 2) as independent variables. When adjusted for the false discovery rate, [total-Hb]sup was positively correlated with glycine and asparagine levels in men and with the serine level in both men and women and was negatively correlated with the branched-chain AA concentration in men. Models 1 and 2 correlated with higher or lower BAT-d for men (r = 0.73, p = 0.015) and women (r = 0.58, p = 0.079) and for men (r = 0.82, p = 0.0070) and women (r = 0.70, p = 0.020), respectively. A combination of anthropometric parameters and plasma AA concentrations could be a reliable biomarker for higher and lower BAT-d.
Miyuki Kuroiwa; Sayuri Hamaoka-Fuse; Masahiro Sugimoto; Yuko Kurosawa; Yasuko Aita; Atsumi Tomita; Mikiko Anjo; Riki Tanaka; Tasuki Endo; Ryotaro Kime; Takafumi Hamaoka. Correlation of Plasma Amino Acid and Anthropometric Profiles with Brown Adipose Tissue Density in Humans. Journal of Clinical Medicine 2021, 10, 2339 .
AMA StyleMiyuki Kuroiwa, Sayuri Hamaoka-Fuse, Masahiro Sugimoto, Yuko Kurosawa, Yasuko Aita, Atsumi Tomita, Mikiko Anjo, Riki Tanaka, Tasuki Endo, Ryotaro Kime, Takafumi Hamaoka. Correlation of Plasma Amino Acid and Anthropometric Profiles with Brown Adipose Tissue Density in Humans. Journal of Clinical Medicine. 2021; 10 (11):2339.
Chicago/Turabian StyleMiyuki Kuroiwa; Sayuri Hamaoka-Fuse; Masahiro Sugimoto; Yuko Kurosawa; Yasuko Aita; Atsumi Tomita; Mikiko Anjo; Riki Tanaka; Tasuki Endo; Ryotaro Kime; Takafumi Hamaoka. 2021. "Correlation of Plasma Amino Acid and Anthropometric Profiles with Brown Adipose Tissue Density in Humans." Journal of Clinical Medicine 10, no. 11: 2339.
Capsinoids are some of the most promising ingredients to increase energy expenditure (EE) due to brown adipose tissue (BAT) activation. However, there is limited information regarding the effect of prolonged capsinoid ingestion (CI) on BAT activity and resting EE (REE) in healthy, middle-aged, normal to overweight subjects (Subhealthy) with distinct BAT characteristics. We examined the changes in BAT density (BAT-d), using near-infrared time-resolved spectroscopy, and REE/kg induced by daily CI. Forty Subhealthy [age, 43.8 (mean) years; BMI, 25.4 kg/m2] received either capsinoid (9 mg/day) or a placebo daily for 6 weeks in a double-blind design. Total hemoglobin concentration in the supraclavicular region ([total-Hb]sup), an indicator of BAT-d, and REE/kg were measured. The changes in post-intervention [total-Hb]sup were greater in the capsinoid group (CA-G) than in the placebo group (PL-G) [5.8 µM (+12.4%) versus 1.0 µM (+2.1%); P = 0.017]. There was a significant relationship between BAT-d and REE/kg; however, post-supplementation REE/kg was not significantly different between the two groups (P = 0.228). In the overweight subgroup, changes in REE/kg were greater in the CA-G than in the PL-G [0.6 cal/kg/min (+4.3%) versus −0.3 cal/kg/min (−2.1%); P = 0.021]. CI enhanced [total-Hb]sup, a reflection of BAT-d, showing a good correlation with REE in Subhealthy.
Sayuri Fuse; Tasuki Endo; Riki Tanaka; Miyuki Kuroiwa; Akira Ando; Ayami Kume; Akiko Yamamoto; Kanna Kuribayashi; Shinji Somekawa; Masamichi Takeshita; Masaki Hashimoto; Ryotaro Kime; Yuko Kurosawa; Takafumi Hamaoka. Effects of Capsinoid Intake on Brown Adipose Tissue Vascular Density and Resting Energy Expenditure in Healthy, Middle-Aged Adults: A Randomized, Double-Blind, Placebo-Controlled Study. Nutrients 2020, 12, 2676 .
AMA StyleSayuri Fuse, Tasuki Endo, Riki Tanaka, Miyuki Kuroiwa, Akira Ando, Ayami Kume, Akiko Yamamoto, Kanna Kuribayashi, Shinji Somekawa, Masamichi Takeshita, Masaki Hashimoto, Ryotaro Kime, Yuko Kurosawa, Takafumi Hamaoka. Effects of Capsinoid Intake on Brown Adipose Tissue Vascular Density and Resting Energy Expenditure in Healthy, Middle-Aged Adults: A Randomized, Double-Blind, Placebo-Controlled Study. Nutrients. 2020; 12 (9):2676.
Chicago/Turabian StyleSayuri Fuse; Tasuki Endo; Riki Tanaka; Miyuki Kuroiwa; Akira Ando; Ayami Kume; Akiko Yamamoto; Kanna Kuribayashi; Shinji Somekawa; Masamichi Takeshita; Masaki Hashimoto; Ryotaro Kime; Yuko Kurosawa; Takafumi Hamaoka. 2020. "Effects of Capsinoid Intake on Brown Adipose Tissue Vascular Density and Resting Energy Expenditure in Healthy, Middle-Aged Adults: A Randomized, Double-Blind, Placebo-Controlled Study." Nutrients 12, no. 9: 2676.
Brown adipose tissue (BAT) plays a role in adaptive thermogenesis in response to cold environments and dietary intake via sympathetic nervous system (SNS) activation. It is unclear whether physical activity increases BAT density (BAT-d). Two-hundred ninety-eight participants (age: 41.2 ± 12.1 (mean ± standard deviation), height: 163.6 ± 8.3 cm, weight: 60.2 ± 11.0 kg, body mass index (BMI): 22.4 ± 3.0 kg/m2, body fat percentage: 25.4 ± 7.5%) without smoking habits were categorized based on their physical activity levels (a group performing physical activities including walking and moderate physical activity (WM) and a group performing WM + vigorous-intensity physical activities (VWM)). We measured the total hemoglobin concentration ([Total-Hb]) in the supraclavicular region, an index of BAT-d, and anthropometric parameters. [Total-Hb] was significantly higher in VWM than WM for all participant groups presumably owing to SNS activation during vigorous-intensity physical activities, and unrelated to the amount of total physical activity levels. Furthermore, multiple regression analysis revealed that BAT-d was related to visceral fat area and VWM in men and related to body fat percentage in women. We conclude that vigorous-intensity physical activities are associated with high BAT-d in humans, especially in men.
Riki Tanaka; Sayuri Fuse; Miyuki Kuroiwa; Shiho Amagasa; Tasuki Endo; Akira Ando; Ryotaro Kime; Yuko Kurosawa; Takafumi Hamaoka. Vigorous-Intensity Physical Activities Are Associated with High Brown Adipose Tissue Density in Humans. International Journal of Environmental Research and Public Health 2020, 17, 2796 .
AMA StyleRiki Tanaka, Sayuri Fuse, Miyuki Kuroiwa, Shiho Amagasa, Tasuki Endo, Akira Ando, Ryotaro Kime, Yuko Kurosawa, Takafumi Hamaoka. Vigorous-Intensity Physical Activities Are Associated with High Brown Adipose Tissue Density in Humans. International Journal of Environmental Research and Public Health. 2020; 17 (8):2796.
Chicago/Turabian StyleRiki Tanaka; Sayuri Fuse; Miyuki Kuroiwa; Shiho Amagasa; Tasuki Endo; Akira Ando; Ryotaro Kime; Yuko Kurosawa; Takafumi Hamaoka. 2020. "Vigorous-Intensity Physical Activities Are Associated with High Brown Adipose Tissue Density in Humans." International Journal of Environmental Research and Public Health 17, no. 8: 2796.
High whole-body and visceral adiposity are risk factors that can cause metabolic diseases. We hypothesized that the total hemoglobin concentration (total-Hb) in abdominal subcutaneous adipose tissue (SATab), an indicator of white adipose tissue (WAT) vascularity, correlates negatively with risk factors for developing metabolic diseases, such as whole-body and visceral adiposity. We tested the optical characteristics of abdominal tissue in 140 participants (45 men and 95 women) who were apparently healthy individuals with a median age of 39 years. They also had a median body fat percentage of 25.4%, a visceral fat area of 50.4 cm2, and a SATab thickness of 1.05 cm. These tests were conducted using near-infrared time-resolved spectroscopy (NIRTRS) with a 2-cm optode separation. To distinguish the segments of SATab (SegSAT) and the mixture of muscle and SATab (SegSAT+Mus), the threshold was analyzed using the slopes of (total-Hb) against the thickness of SATab using the least-squares mean method. According to the results from the logistic regression analysis, the percentage of body fat and visceral fat area remained significant predictors of the (total-Hb) (p = 0.005 and p = 0.043, respectively) in the data for SegSAT (no influence from the SATab thickness). We conclude that simple, rapid, and noninvasive NIRTRS-determined (total-Hb) in WAT could be a useful parameter for evaluating risk factors for metabolic diseases.
Miyuki Kuroiwa; Sayuri Fuse; Shiho Amagasa; Ryotaro Kime; Tasuki Endo; Yuko Kurosawa; Takafumi Hamaoka. Relationship of Total Hemoglobin in Subcutaneous Adipose Tissue with Whole-Body and Visceral Adiposity in Humans. Applied Sciences 2019, 9, 2442 .
AMA StyleMiyuki Kuroiwa, Sayuri Fuse, Shiho Amagasa, Ryotaro Kime, Tasuki Endo, Yuko Kurosawa, Takafumi Hamaoka. Relationship of Total Hemoglobin in Subcutaneous Adipose Tissue with Whole-Body and Visceral Adiposity in Humans. Applied Sciences. 2019; 9 (12):2442.
Chicago/Turabian StyleMiyuki Kuroiwa; Sayuri Fuse; Shiho Amagasa; Ryotaro Kime; Tasuki Endo; Yuko Kurosawa; Takafumi Hamaoka. 2019. "Relationship of Total Hemoglobin in Subcutaneous Adipose Tissue with Whole-Body and Visceral Adiposity in Humans." Applied Sciences 9, no. 12: 2442.
Brown adipose tissue (BAT) may potentially be used in strategies for preventing lifestyle-related diseases. We examine evidence that near-infrared time-resolved spectroscopy (NIRTRS) is capable of estimating human BAT density (BAT-d). The parameters examined in this study are total hemoglobin [total-Hb]sup, oxygenated Hb [oxy-Hb]sup, deoxygenated Hb [deoxy-Hb]sup, Hb O2 saturation (StO2sup), and the reduced scattering coefficient in the supraclavicular region (μs'sup), where BAT deposits can be located; corresponding parameters in the control deltoid region are obtained as controls. Among the NIRTRS parameters, [total-Hb]sup and [oxy-Hb]sup show region-specific increases in winter, compared to summer. Further, [total-Hb]sup and [oxy-Hb]sup are correlated with cold-induced thermogenesis in the supraclavicular region. We conclude that NIRTRS-determined [total-Hb]sup and [oxy-Hb]sup are useful parameters for evaluating BAT-d in a simple, rapid, non-invasive manner.
Shinsuke Nirengi; Sayuri Fuse; Shiho Amagasa; Toshiyuki Homma; Ryotaro Kime; Miyuki Kuroiwa; Tasuki Endo; Naoki Sakane; Mami Matsushita; Masayuki Saito; Yuko Kurosawa; Takafumi Hamaoka. Applicability of Supraclavicular Oxygenated and Total Hemoglobin Evaluated by Near-Infrared Time-Resolved Spectroscopy as Indicators of Brown Adipose Tissue Density in Humans. International Journal of Molecular Sciences 2019, 20, 2214 .
AMA StyleShinsuke Nirengi, Sayuri Fuse, Shiho Amagasa, Toshiyuki Homma, Ryotaro Kime, Miyuki Kuroiwa, Tasuki Endo, Naoki Sakane, Mami Matsushita, Masayuki Saito, Yuko Kurosawa, Takafumi Hamaoka. Applicability of Supraclavicular Oxygenated and Total Hemoglobin Evaluated by Near-Infrared Time-Resolved Spectroscopy as Indicators of Brown Adipose Tissue Density in Humans. International Journal of Molecular Sciences. 2019; 20 (9):2214.
Chicago/Turabian StyleShinsuke Nirengi; Sayuri Fuse; Shiho Amagasa; Toshiyuki Homma; Ryotaro Kime; Miyuki Kuroiwa; Tasuki Endo; Naoki Sakane; Mami Matsushita; Masayuki Saito; Yuko Kurosawa; Takafumi Hamaoka. 2019. "Applicability of Supraclavicular Oxygenated and Total Hemoglobin Evaluated by Near-Infrared Time-Resolved Spectroscopy as Indicators of Brown Adipose Tissue Density in Humans." International Journal of Molecular Sciences 20, no. 9: 2214.
This study quantitatively analyzed the effects of 3 h of constant sitting on skeletal muscle oxygenation in the lower extremities, using near-infrared time-resolved spectroscopy (NIRTRS). The effects of compression stockings were also evaluated. Eleven healthy men (age, 30.0 ± 6.7 years) maintained their knee joints at 90° flexion during 3 h of constant sitting and wore a compression stocking on either the right or left leg. The side the stocking was worn was chosen randomly. Subsequently, leg circumference and extracellular water were measured. After 3 h of sitting, both factors increased significantly in uncompressed limbs. Furthermore, intracellular water and muscle oxygenation had significantly decreased. In contrast, extracellular water had not increased in the limbs wearing compression stockings. Furthermore, the increased circumference of compressed limbs was significantly smaller than that of uncompressed limbs. Decreases in oxygenated hemoglobin and total hemoglobin were significantly smaller in compressed limbs than in uncompressed limbs (oxy-Hb; p = 0.021, total-Hb; p = 0.013). Three hours of sitting resulted in decreased intracellular water and increased extracellular water in the lower extremities, leading to reduced blood volume and oxygenation levels in skeletal muscle. Compression stockings successfully suppressed these negative effects.
Misato Kinoshita; Yuko Kurosawa; Sayuri Fuse; Riki Tanaka; Nobuko Tano; Ryota Kobayashi; Ryotaro Kime; Takafumi Hamaoka. Compression Stockings Suppressed Reduced Muscle Blood Volume and Oxygenation Levels Induced by Persistent Sitting. Applied Sciences 2019, 9, 1800 .
AMA StyleMisato Kinoshita, Yuko Kurosawa, Sayuri Fuse, Riki Tanaka, Nobuko Tano, Ryota Kobayashi, Ryotaro Kime, Takafumi Hamaoka. Compression Stockings Suppressed Reduced Muscle Blood Volume and Oxygenation Levels Induced by Persistent Sitting. Applied Sciences. 2019; 9 (9):1800.
Chicago/Turabian StyleMisato Kinoshita; Yuko Kurosawa; Sayuri Fuse; Riki Tanaka; Nobuko Tano; Ryota Kobayashi; Ryotaro Kime; Takafumi Hamaoka. 2019. "Compression Stockings Suppressed Reduced Muscle Blood Volume and Oxygenation Levels Induced by Persistent Sitting." Applied Sciences 9, no. 9: 1800.
Background: Near-infrared time-resolved spectroscopy is a non-invasive method that facilitates analysis of human brown adipose tissue (BAT) density. We measured BAT density in middle-aged patients who had type 2 diabetes by this method and examined the relationship using clinical parameters. Methods: We studied 33 Japanese middle-aged diabetic patients (30 male and 3 female, age 53.8±10.1 years, BMI 25.4±4.5, and HbA1c 7.2±1.1%). Tissue hemoglobin concentration (tHb) of the supraclavicular region was measured using near-infrared time-resolved spectroscopy, and normalized by subcutaneous fat thickness at the measurement sites. Results: The average tHb concentration was 51.1±17.7 μM and lower than 77.8 μM—the value equivalent to the detection threshold of BAT by standard FDG-PET in young adults. Univariate regression analysis showed that the tHb of the supraclavicular region was inversely correlated with BMI (r = −0.55, p=0.0009), but the tHb of the deltoid region was not (r = 0.04, p = 0.31). Other parameters showing significant correlations with BAT mass included systolic blood pressure (r = −0.47, p = 0.01) and insulin treatment (r=0.45, p=0.01). Multivariate regression analysis suggested that BMI (β=−0.42, p=0.005), systolic blood pressure (β=−0.29, p=0.042), and insulin treatment (β=0.34, p=0.015) independently account for BAT density. Conclusion: Our findings suggest that BAT density in middle-aged diabetic patients may relate to obesity more closely than previously thought. Disclosure H. Waki: Research Support; Self; MSD K.K., Novartis Pharma K.K., Boehringer Ingelheim Pharmaceuticals, Inc., Sanofi K.K., Ono Pharmaceutical Co., Ltd., Kyowa Hakko Kirin Co., Ltd., Takeda PHarmaceutical Co., Ltd.. N. Watanabe: None. S. Fuse: None. Y. Kurosawa: None. T. Yamauchi: Research Support; Self; Novo Nordisk Inc., Daiichi Sankyo Company, Limited, Sanofi, Takeda, Tanabe-Mitsubishi. R. Kime: None. T. Hamaoka: None. T. Kadowaki: Consultant; Self; Novo Nordisk A/S, AstraZeneca, Merck Sharp & Dohme Corp.. Research Support; Self; Kissei Pharmaceutical Co., Ltd., Taisho Pharmaceutical Co., Ltd., Sanofi, Kyowa Hakko Kirin Co., Ltd., Novo Nordisk A/S, Astellas Pharma, Daiichi Sankyo Company, Limited, Takeda, Mitsubishi Tanabe Pharma Corporation, Ono Pharmaceutical Co., Ltd., Merck Sharp & Dohme Corp., Nippon Boehringer Ingelheim Co. Ltd.. Speaker9s Bureau; Self; Astellas Pharma, AstraZeneca, Merck Sharp & Dohme Corp., Ono Pharmaceutical Co., Ltd., Takeda, Eli Lilly and Company, Nippon Boehringer Ingelheim Co. Ltd., Novo Nordisk A/S.
Hironori Waki; Naoko Watanabe; Sayuri Fuse; Yuko Kurosawa; Toshimasa Yamauchi; Ryotaro Kime; Takafumi Hamaoka; Takashi Kadowaki. Human Brown Adipose Tissue Density Assessed by Near-Infrared Time-Resolved Spectroscopy Inversely Correlates with the Body Mass Index in Patients with Type 2 Diabetes. Diabetes 2018, 67, 2080 .
AMA StyleHironori Waki, Naoko Watanabe, Sayuri Fuse, Yuko Kurosawa, Toshimasa Yamauchi, Ryotaro Kime, Takafumi Hamaoka, Takashi Kadowaki. Human Brown Adipose Tissue Density Assessed by Near-Infrared Time-Resolved Spectroscopy Inversely Correlates with the Body Mass Index in Patients with Type 2 Diabetes. Diabetes. 2018; 67 (Supplement):2080.
Chicago/Turabian StyleHironori Waki; Naoko Watanabe; Sayuri Fuse; Yuko Kurosawa; Toshimasa Yamauchi; Ryotaro Kime; Takafumi Hamaoka; Takashi Kadowaki. 2018. "Human Brown Adipose Tissue Density Assessed by Near-Infrared Time-Resolved Spectroscopy Inversely Correlates with the Body Mass Index in Patients with Type 2 Diabetes." Diabetes 67, no. Supplement: 2080.
F18-fluorodeoxyglucose (FDG)–positron emission tomography (PET) along with computed tomography (CT) is a standard method for assessing brown adipose tissue (BAT) activity. We tested the usefulness of near-infrared time-resolved spectroscopy (NIRTRS) as a simple and noninvasive method for evaluating BAT density (BAT-d) by examining the effects of some factors known to influence BAT activity. The total hemoglobin concentration as a parameter of BAT-d was evaluated using NIRTRS in the supraclavicular region in 413 Japanese individuals. The associations were analyzed between BAT-d and sex, age, the percentages of body fat (%BF), visceral fat (VF), and the seasonal ambient temperature (AmT) fluctuations. Age was associated with decreased BAT-d (P < 0.05). There was no sex difference in the BAT-d, except for those in their twenties. Multivariate analyses revealed that %BF and VF were correlated with BAT-d, and the lower AmT (around 4°C or 5°C) for 4 and 6 weeks prior to the measurement day was associated with an increase in the BAT-d. Our NIRTRS results were analogous to those reported with FDG18-PET / CT, indicating the usefulness of NIRTRS. BAT-d might increase during the 4 and 6 weeks after the AmT decreases to lower than 4°C or 5°C. Fuse, Nirengi, Amagasa, Homma, Kime, Endo, Sakane, Matsushita, Saito, Yoneshiro, Kurosawa, and Hamaoka: Brown adipose tissue density measured by near-infrared time-resolved spectroscopy in Japanese, across a wide age range1.IntroductionActive brown adipose tissue (BAT) has been detected by F18-fluorodeoxyglucose (FDG)–positron emission tomography (PET) combined with computed tomography (CT)12.3.–4 in adults and neonates, as well as animals. It has been reported that human BAT activity is related to cold-induced thermogenesis,5 body weight,5 and glucose tolerance.6,7 Furthermore, daily cold exposure increased the BAT activity in healthy individuals,5,8,9 obese individuals,10 and patients with type 2 diabetes.7 Thus, BAT is expected to be a potential tool to combat obesity and lifestyle-related diseases.Most epidemiological studies related to BAT have been informed by work in oncology and used FDG18-PET/CT in thermoneutral conditions. These data showed that BAT activity was higher in women, younger individuals, and lean patients, as well as under conditions of lower ambient temperatures (AmT).1112.13.14.15.16.–17 However, since these data were collected for the diagnosis of cancer, data on healthy adults were lacking, and the mean age was biased toward patients older than 60 years of age. In addition, the measurements were conducted under thermoneutral conditions, wherein the FDG uptake might have been underestimated.1,18 Indeed, the FDG18-PET/CT-positive BAT ratio is variable; in studies involving cancer patients without cold exposure, the ratio was found to be extremely low (∼5%).1112.13.14.15.16.–17,19,20 However, in younger healthy individuals, who were exposed to cold, the ratio was much higher...
Sayuri Fuse; Shinsuke Nirengi; Shiho Amagasa; Toshiyuki Homma; Ryotaro Kime; Tasuki Endo; Naoki Sakane; Mami Matsushita; Masayuki Saito; Takeshi Yoneshiro; Yuko Kurosawa; Takafumi Hamaoka. Brown adipose tissue density measured by near-infrared time-resolved spectroscopy in Japanese, across a wide age range. Journal of Biomedical Optics 2018, 23, 065002 .
AMA StyleSayuri Fuse, Shinsuke Nirengi, Shiho Amagasa, Toshiyuki Homma, Ryotaro Kime, Tasuki Endo, Naoki Sakane, Mami Matsushita, Masayuki Saito, Takeshi Yoneshiro, Yuko Kurosawa, Takafumi Hamaoka. Brown adipose tissue density measured by near-infrared time-resolved spectroscopy in Japanese, across a wide age range. Journal of Biomedical Optics. 2018; 23 (6):065002.
Chicago/Turabian StyleSayuri Fuse; Shinsuke Nirengi; Shiho Amagasa; Toshiyuki Homma; Ryotaro Kime; Tasuki Endo; Naoki Sakane; Mami Matsushita; Masayuki Saito; Takeshi Yoneshiro; Yuko Kurosawa; Takafumi Hamaoka. 2018. "Brown adipose tissue density measured by near-infrared time-resolved spectroscopy in Japanese, across a wide age range." Journal of Biomedical Optics 23, no. 6: 065002.
Sayuri Fuse; Ryotaro Kime; Takuya Osada; Norio Murase; Toshihito Katsumura. Erratum to: The Effects of Passive Cycling Exercise for 20 min on Cardiorespiratory Dynamics in Healthy Men. Advances in Experimental Medicine and Biology 2016, 923, E1 -E1.
AMA StyleSayuri Fuse, Ryotaro Kime, Takuya Osada, Norio Murase, Toshihito Katsumura. Erratum to: The Effects of Passive Cycling Exercise for 20 min on Cardiorespiratory Dynamics in Healthy Men. Advances in Experimental Medicine and Biology. 2016; 923 ():E1-E1.
Chicago/Turabian StyleSayuri Fuse; Ryotaro Kime; Takuya Osada; Norio Murase; Toshihito Katsumura. 2016. "Erratum to: The Effects of Passive Cycling Exercise for 20 min on Cardiorespiratory Dynamics in Healthy Men." Advances in Experimental Medicine and Biology 923, no. : E1-E1.
An increase in the incidence rate of cardiovascular disease is attributed to high daily sitting time, while a drop in risk of cardiovascular disease comes from a decrease in daily sitting time, rather than an increase in physical activity levels. Although short-duration passive exercise increases energy expenditure and blood flow, few studies have reported on the responses of cardiorespiratory dynamics to long-duration passive exercise. The purpose of this study was to consider the effect of long-duration passive exercise for 20 min on cardiorespiratory and muscle oxygen dynamics. Eight healthy men continuously performed passive exercise using a cycle ergometer for 20 min at 50 rpm. Changes in oxygen uptake, cardiac output and muscle oxygenation were measured during passive cycling exercise. The oxygen uptake at 1 min after the start of passive exercise was significantly increased, compared to resting level, but subsequently returned to the same as resting level. Cardiac output showed no change during passive cycling exercise. Tissue oxygen saturation increased after the start of passive exercise and subsequently maintained steady state. These results suggest that the effect of increases in energy expenditure was not maintained by passive exercise for 20 min. In addition, it is likely that passive cycling exercise for 20 min has an effect on peripheral circulation, although the exercise seems to have no effect on central circulation.
Sayuri Fuse; Ryotaro Kime; Takuya Osada; Norio Murase; Toshihito Katsumura. The Effects of Passive Cycling Exercise for 20 min on Cardiorespiratory Dynamics in Healthy Men [corrected]. Single Molecule and Single Cell Sequencing 2016, 923, 263 -268.
AMA StyleSayuri Fuse, Ryotaro Kime, Takuya Osada, Norio Murase, Toshihito Katsumura. The Effects of Passive Cycling Exercise for 20 min on Cardiorespiratory Dynamics in Healthy Men [corrected]. Single Molecule and Single Cell Sequencing. 2016; 923 ():263-268.
Chicago/Turabian StyleSayuri Fuse; Ryotaro Kime; Takuya Osada; Norio Murase; Toshihito Katsumura. 2016. "The Effects of Passive Cycling Exercise for 20 min on Cardiorespiratory Dynamics in Healthy Men [corrected]." Single Molecule and Single Cell Sequencing 923, no. : 263-268.