Nanomedicine is the application of nanotechnology to the diagnosis and treatment of human disease. This discipline has the potential to change medical science dramatically, for example as demonstrated by an innovation in cancer imaging that uses novel diagnostic agents synthesized from nanoparticles. Some research on cluster-based materials for future medical applications is described in this paper. The design of a multifunctional photosensitive particle that is stable and highly efficient will be key to this novel medical application and especially in photodynamic treatment (PDT). Three consecutive processes occur during the PDT treatment: initial consumption of oxygen through the photodynamic process; pathophysiologic alterations in regional blood supply (hypoxia) and total vascular occlusion (ischemia). The effect of a new drug TiO2/TSPP was studied work. Cancer cells were implanted under the skin of mice to cause tumors. When the size of the tumor grew to about 0.5 cm, it was injected a solution containing fine particles of TiO2/TSPP. After 2 or 3 days, the skin was cut to expose the tumor and irradiated. The treatment clearly inhibited the tumor growth. A further marked antineoplastic effect was obtained.

This paper presents experimental research on the relationship between the magnetic properties and the viscosity of ferrofluid based on ultra-pure magnetite nanoparticles, with the aim of studying behaviour through a microchannel. The magnetite nanoparticles have been obtained by chemical coprecipitation. Some examination methods, such as X-ray diffraction, transmission electron microscopy, and vibrating sample magnetometer, have been used to characterize the magnetite nanoparticles. The variation on the viscosity in the magnetic field of ferrofluids based on superparamagnetic magnetite has parabolic allure and in the absence of the magnetic field has a linear allure. The colloidal stability of the ferrofluids was evaluated using zeta potential measurements. Also, the behaviour of ferrofluids in a microchannel made inside the transparent polydimethylsiloxane (PDMS) matrix was observed under a digital microscope.

Photodynamic therapy is a method that provides a reasonable alternative to other treatment modalities for patients with certain cancers, and in some cases may be the preferred treatment. The therapy implies the intravenous administration of a light-sensitive substance, the photosensitizer. The used sensitizer must absorb at long wavelength. For these purposes, the carbon dioxide laser, He-Ne and the argon laser are particularly suitable. In this study we evaluate in vitro the cytotoxic activity of three synthesized metallo-phthalocyanines with absorption bands in the red part of the spectrum: zinc-di-sulphonated phthalocyanine (ZnS₂Pc), zinc-tri-sulphonated phthalocyanine (ZnS₃Pc) and zinc-tetrasulphonated phthalocyanine (ZnS₄Pc). Some cellular models have been used in this paper, in order to optimize the conditions of this method, as we are presenting in this paper (LSR-SF(SR) - transplantable sarcoma in rat induced by Rous sarcoma virus strain Schmidt-Ruppin; LSCC-SF(Mc29) - transplantable chicken hepatoma induced by the myelocytomatosis virus Mc29, MCF-7 cell line (human breast adenocarcinoma) derived from a patient with metastatic breast cancer, 8-MG-BA - glioblastoma multiforme 8-MG-BA, K562 - lymphoblastic human cell line, LLC-WRC 256 - Walker epithelial carcinoma. Activation of these photosensitizers retained in the cancerous cells, by red light emitted from a He-Ne laser at &lgr;= 632.8 nm laser system, or by a diode laser emitting at 672 nm, produces a photochemical reaction that results in the selective destruction of tumor cells.

This paper presents the results of archaeometric research on the white and red materials used to decorate some ceramic vessels belonging to the Boian culture, the Vidra and Spanţov phases from the 5th millennium BC, discovered at Hârşova-Tell, on the right bank of the Danube, Romania. Digital microscopy, wavelength-dispersive X-ray fluorescence spectroscopy, X-ray diffraction, and Fourier transform infrared spectroscopy were used to identify the morphology, the crystalline phases, chemical formula, and percentage content of each crystalline phase in the white decoration materials and what type of pigment was used to prepare the red paint. The results obtained reveal that the white decorating material in the pottery is mostly made of calcite. It was added after the pottery was fired. Sometimes, powders from burnt bones were also used. The red pigment is hematite. The work contributes to the completion of a puzzle related to the artistic vision of the members of the Boian communities in decorating ceramics with culture-specific motifs, preserving the pattern, and adapting to the local natural resources.

In order to improve the anticorrosion protection properties, polypyrrole thin films were deposited on silicon steel plates. The anticorrosive protection effect of the polypriol coating was evaluated by electrochemical measurements in two different aqueous solutions of potassium chloride and hydrochloric acid. Polypyrrole-coated silicon steel plates were immersed for one and seven days, respectively. The obtained results show that the thin layer of polypyrrole ensures effective protection of silicon steel against corrosion, especially in aqueous potassium chloride solution.