The aim of this study was to develop and verify a personalised approach for simulating the aerodynamic flow patterns using patient-specific data of a severe form of nasal obstruction during inspiration. The reconstruction of the 3D geometry of the nasal cavity based on the computer images of a patient diagnosed with the unilateral nasal valve collapse and S-shaped septum deviation was used to perform the Computational Fluid Dynamics (CFD) simulation of airflow. A comparative study of the airflow with standard data (SD) and personal input data (PD) of mass flow rate was carried out. In both cases, the air streamlines went straight along the lower and middle nasal passages on the non-deviated septum side. The peak velocity increased in two cavities, mostly on the septum deviation side, while the peak pressure inversely dropped. . With personal data, the peak velocity and pressure values varied greatly in different parts of the nasal cavity, depending on the particular local anatomy. In a patient with unilateral nasal valve collapse and S-shaped septum deviation, the use of personal data does not have an impact on the streamline’s direction, longitudinal velocity, and pressure distributions but it significantly changed the local velocity and pressure in the nasal cavity.

Background: Occupational bronchopulmonary diseases (OBPDs)—including pneumoconiosis, silicosis, and occupational COPD—remain a pressing public health issue, especially in regions with intensive mining, metallurgy, and construction industries. Caused by chronic inhalation of fibrogenic dusts, these conditions are often diagnosed at late stages, resulting in irreversible lung damage and diminished work capacity. Methods: A scoping review was performed using the Arksey and O’Malley framework, with methodological refinements from the Joanna Briggs Institute. Following PRISMA-ScR guidelines, we searched PubMed, Scopus, and gray literature for publications from 2014 to 2024. After screening 1761 records and full-text review, nine studies were included in the final synthesis, comprising two systematic reviews, two narrative literature reviews, and five observational studies. Results: Key risk factors identified included prolonged exposure to silica and coal dust, tobacco use, and genetic susceptibility. Diagnostic delays were attributed to the underuse of high-resolution CT and exhaled nitric oxide analysis. Several studies highlighted the diagnostic value of oxidative stress and inflammatory markers (e.g., IL-6, TNF-α). Nutritional rehabilitation and polyphenol-enriched herbal therapies were associated with improved respiratory function and quality of life. However, these strategies remain underutilized, particularly in low-resource settings. Conclusions: A coordinated, biomarker-driven approach integrating early diagnosis, dust exposure control, and tailored rehabilitation is urgently needed. Multidisciplinary models may reduce the clinical and socioeconomic burden of OBPDs.

Background. Recurrent respiratory papillomatosis (RRP) in children remains a pressing issue in pediatric otolaryngology, characterized by a chronic course, frequent relapses, and the need for repeat surgical interventions. The aim of this study was to evaluate whether the surgical technique used for primary removal of pediatric RRP—CO₂ laser, microdebrider, or a combined approach—was associated with clinically documented recurrence and early recurrence within 12 months. Materials and Methods. A retrospective study of 53 medical records of children who underwent their first surgery for RRP between 2019 and 2023 was conducted. Three surgical approaches were used: CO₂ laser, microdebrider, and a combined method. Statistical analysis was performed using Pearson’s χ² test, and the strength of association was evaluated with Cramér’s V. Results. The most frequently used method was the CO₂ laser (n = 25), followed by a microdebrider (n = 16), and a combined method (n = 12). During the observation period, disease recurrence was recorded in 35 of 53 patients (66.0%): in 20 children, within the first 12 months after surgery, and in 15, after more than 12 months. No recurrence was documented in the available medical records for 18 patients during the observation period. No statistically significant effect of the surgical treatment method on the recurrence rate (p = 0.813) or the risk of early recurrence (p = 0.926) was found. Also, no significant association was found between the child’s age and either the overall recurrence rate (p = 0.510) or the likelihood of early recurrence (p = 0.217). Conclusions. Within the limitations of this retrospective single-center study, neither the surgical treatment method nor the patient’s age was associated with clinically documented recurrence or early recurrence recorded in the available medical records.

Objective. To study the Proetz method mechanism by CFD (computational fluid dynamics) modeling. Material and methods. CFD modeling was performed using a 40-year-old female patient’s CT scans of paranasal sinuses. Modeling is carried out using Mimics Medical 24.0, Ansys Fluent software. Results. When rinsing the nose, the sinuses are filled gradually as liquid sauces are reached after filling the common nasal passage. Fluid removal is effective only from the nasal cavity, the irrigation solution remains in the paranasal sinuses. Conclusion. During the Proetz rinsing method, it is effective for cleaning only the nasal cavity, while the cleaning of paranasal secretions occurs partially, complete aspiration of the irrigation solution from the sinus cavity is impossible.