Yu Zhang

Yu Zhang


Research Focus & Metrics

Academic Career Length

9Years (2018-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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Verified
Journal Article
Open access
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LWli chao wei
li chao wei
YCYue Cheng
Yue Cheng
DLDawei Li
Dawei Li
QAQi An
Qi An
WZWei Zhang
Wei Zhang
YFYijun Fu
Yijun Fu
As a new tumor treatment strategy, photothermal therapy (PTT) has the advantages of accuracy, ease of administration, a high efficiency and low side effects. Photothermal transduction agents (PTAs) are the key factor which play an important role in PTT. The mechanism of PTT is discussed in detail. The photothermal conversion efficiency (PCE) can be improved by increasing the light absorption and reducing the light scattering of photothermal conversion agents. Additionally, non-radiative relaxation path attenuation can also promote energy conversion to obtain a higher value in terms of PCE. The structure and photothermal characteristics of various kinds of PTAs (metal materials, carbon-based nanomaterials, two-dimensional nanomaterials, and organic materials) were compared and analyzed. This paper reviews the antitumor applications of photothermal synergistic therapies, including PTT combined with immunotherapy, chemotherapy, and photodynamic therapy. This review proposes that these PTAs promote the development of photothermal synergistic therapies and have a great potential in the application of tumor treatment.

13 October 2020 in Polymers
Verified
Journal Article
Open access
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HZHaifeng Zhang
Haifeng Zhang
NLNuo Liu
Nuo Liu
QZQianru Zeng
Qianru Zeng
JLJinxin Liu
Jinxin Liu
XZXing Zhang
Xing Zhang
YZYu Zhang
Yu Zhang
Electret filters are widely used in particulate matter filtration due to their filtration efficiency that can be greatly improved by electrostatic forces without sacrificing the air resistance. However, the attenuation of the filtration efficiency remains a challenge. In this study, we report a novel strategy for producing an electret melt blown filter with superior filtration efficiency stability through a thermally stimulated charging method. The proposed approach optimizes the crystal structure and therefore results in the increased production probability of the charge traps. In addition, the re-trapping phenomenon caused by the thermal stimulation during the charging process can greatly increase the proportion of deep charge to shallow charge and improve the charge stability. A superior electret melt blown filtration material with a high filtration efficiency of 99.65%, low pressure drop of 120 Pa, and satisfactory filtration efficiency stability was produced after three cyclic charging times. The excellent filtration performance indicated that the developed material is a good air filtration candidate component for personal protection applications.

6 October 2018 in Molecules
Verified
Journal Article
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YFYijun Fu
Yijun Fu
JDJiamu Dai
Jiamu Dai
YGYan Ge
Yan Ge
YZYu Zhang
Yu Zhang
HKHuizhen Ke
Huizhen Ke
WZWei Zhang
Wei Zhang
A co-based porous metal-organic framework (MOF) of zeolitic imidazolate framework-67 (ZIF-67) and carbon nanofibers (CNFs) was utilized to prepare a ZIF-67/CNFs composite via a one-pot synthesis method. Scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), and X-ray diffraction (XRD) were employed to investigate the morphology, structure, and composition of the resulting composite. A novel high-performance non-enzymatic electrochemical sensor was constructed based on the ZIF-67/CNFs composite. The ZIF-67/CNFs based sensor exhibited enhanced electrocatalytic activity towards H2O2 compared to a pure ZIF-67-based sensor, due to the synergistic effects of ZIF-67 and CNFs. Meanwhile, chronoamperometry was utilized to explore the detection performance of the sensor. Results showed the sensor displayed high-efficiency electrocatalysis towards H2O2 with a detection limit of 0.62 μM (S/N = 3), a sensitivity of 323 µA mM−1 cm−2, a linear range from 0.0025 to 0.19 mM, as well as satisfactory selectivity and long-term stability. Furthermore, the sensor demonstrated its application potential in the detection of H2O2 in food.

8 November 2019 in Polymers
Verified
Journal Article
Open access
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GZGuangyu Zhang
Guangyu Zhang
YXYao Xiao
Yao Xiao
JYJiawei Yan
Jiawei Yan
NXNingwei Xie
Ningwei Xie
RLRong Liu
Rong Liu
YZYu Zhang
Yu Zhang
Herein, ZnO nanoparticles (NPs) were synthesized using zinc acetate and an amino hyperbranched polymer. The methods of transmission electron microscope (TEM) and X-ray Diffraction (XRD) were applied to the characterization of ZnO NPs. Polypropylene (PP)/ZnO fiber was prepared using 1–5 wt% ZnO NPs via melt spinning. The ultraviolet light (UV)-degradation behavior, antibacterial activity and mechanical properties of PP fibers were characterized. The PP fiber filled with ZnO NPs presents better mechanical properties and the resistance to UV light degradation. For the best effect, the contents of ZnO NPs were set 4 wt% in PP fiber. FTIR analysis shows significant photo-degradation of PP induced by UV irradiation and a remarkable reduction in the UV degradation of the fiber filled with ZnO NPs. It is also observed that the ZnO NPs-filled fiber has good antibacterial actives against Escherichia coli and staphylococcus aureus.

23 November 2018 in Discover Nano
Verified
Journal Article
Open access
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WZWei Zhang
Wei Zhang
JDJiamu Dai
Jiamu Dai
GZGuangyu Zhang
Guangyu Zhang
YZYu Zhang
Yu Zhang
SLSuying Li
Suying Li
DNDu Nie
Du Nie
In this paper, a simple method to prepare hydrophilic reduced graphene oxide (rGO) was proposed via reducing GO by amino-terminated hyperbranched polymer (NHBP), the as-prepared NrGO could present excellent dispersibility, near infrared (NIR) light absorbance, photothermal conversion ability and stability. Then, the doxorubicin hydrochloride (DOX) was conjugated with NrGO to prepare the drug-loading system, and a pH/photothermal dual-responsive drug delivery behavior was characterized. At acidic environment or under NIR laser irradiation, the drug release rate could be improved, which is beneficial to control release anti-tumor drug in tumor tissues. What is more, the in vitro cell experiments revealed that NrGO was well biocompatible, and in the tumor inhibition part, comparing to the control group without any treatment, DOX@NrGO gained efficient chemo-photothermal synergetic therapy, the inhibition rate of which was much higher than single chemotherapy of released DOX. Therefore, the as-prepared DOX@NrGO obtained great potential application in tumor therapy and an excellent candidate in other biomed applications.

4 March 2020 in Polymers
Verified
Journal Article
Open access
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RLRong Liu
Rong Liu
SLShusen Liu
Shusen Liu
JYJunrong Yu
Junrong Yu
WZWei Zhang
Wei Zhang
JDJiamu Dai
Jiamu Dai
GZGuangyu Zhang
Guangyu Zhang
In this study, a facile and effective method is adopted to prepare mechanochemically robust super antifouling membrane surfaces. During the process, vinyl trimethoxy silane (VTMS) was used as the reactive intermediate for coupling the hydrophilic inorganic SiO2 nanoparticle layer on to the organic ultra-high-molecular-weight polyethylene (UHMWPE) membrane surface, which created hierarchical nanostructures and lower surface energy simultaneously. The physical and chemical properties of the modified UHMWPE composite membrane surface were investigated. FTIR and XPS showed the successful chemical grafting of VTMS and SiO2 immobilization, and this modification could effectively enhance the membrane’s surface hydrophilicity and filtration property with obviously decreased surface contact angle, the pure water flux and bovine serum albumin (BSA) rejection were 805 L·m−2·h−1 and 93%, respectively. The construction of the hydrophilic nano-SiO2 layer on the composite membrane surface for the improvement of membrane antifouling performance was universal, water flux recovery ratio values of BSA, humic acid (HA), and sodium alginate (SA) were all up to 90%. The aim of this paper is to provide an effective approach for the enhancement of membrane antifouling performance by the construction of a hydrophilic inorganic layer on an organic membrane surface.