We demonstrated a novel fiber in-line Mach-Zehnder interferometer (MZI) with a large fringe visibility of up to 17 dB, which was fabricated by misaligned splicing a short section of thin core fiber between two sections of standard single-mode fiber. Such a MZI could be used to realize simultaneous measurement of tensile strain and temperature. Tensile strain was measured with an ultrahigh sensitivity of −0.023 dB/μɛ via the intensity modulation of interference fringes, and temperature was measured with a high sensitivity of 51 pm/°C via the wavelength modulation of interference fringe. That is, the MZI-based sensor overcomes the cross-sensitivity problem between tensile strain and temperature by means of different demodulation methods. Moreover, this proposed sensor exhibits the advantages of low-cost, extremely simple structure, compact size (only about 10 mm), and good repeatability.

A high-sensitivity and low-temperature fiber-optic magnetic field sensor based on a tapered two-mode fiber (TTMF) sandwiched between two single-mode fibers has been proposed and demonstrated. The section of TTMF has a specifically designed transition region as an efficient tool to filter higher-order modes, where the uniform modal interferometer just involved with ${\mathrm{LP}}_{01}$ and ${\mathrm{LP}}_{11}$ modes is achieved. The transmission spectral characteristics and the magnetic response of the proposed sensors have been investigated. The experimental results show that a maximum sensitivity of $98.2\mathrm{pm}/\mathrm{Oe}$ within a linear magnetic field intensity ranging from 0 to 140 Oe can be achieved. Significantly, the temperature cross-sensitivity problem can be resolved owing to the lower thermal expansion coefficient of the TTMF. Finally, with its low insertion loss, compactness, and ease of fabrication, the proposed sensor would find potential applications in the measurement of a magnetic field.

We experimentally demonstrate an automatic arc discharge technology for inscribing high-quality helically twisted long period fiber gratings (H-LPFGs) with greatly improved inscription efficiency for single mode fibers. The proposed technology has been developed by implementing an embedded program in a commercial fusion splicer, which employs an ultraprecision motorized translation stage while the tensioning mass required by conventional inscribing technology is eliminated. More significantly, the arc-induced H-LPFGs have been reported to have potential usage as sensors in temperature, refractive index, twist stress, and strain.

A sensitivity enhanced temperature sensor with cascaded tapered two-mode fibers (TTMFs) based on the Vernier effect is proposed and experimentally demonstrated. It is confirmed that series connection exhibits higher extinction ratio than parallel one both by theory and experiments, which provides guidance for related experiments. In experiments, two TTMFs have the same single-mode fiber-TTMF-single-mode fiber configuration, while the free spectral ranges (FSRs) are chosen with slightly difference by modifying the parameters in the tapering process. Experimental results show that the proposed temperature sensor possesses sensitivity of −3.348 nm/°C in temperature measurement range from 25 °C to 60°C, 11.3 times sensitivity enhancement in comparison with single TTMF. Benefiting from advantages of high temperature sensitivity, simplicity of manufacture and long distance sensing, this novel sensitivity enhanced temperature sensor can be applied to various particular fields, such as oil wells, coal mines and so on.

Background: The physical factors of the extracellular matrix have a profound influence on the differentiation behavior of mesenchymal stem cells. In this study, the effect of the biophysical microenvironment on rat bone marrow mesenchymal stem cell (BMSC) osteogenesis was studied both in vitro and in vivo. Methods: To prepare cell culture scaffolds of varying stiffness, increasing amounts of hydroxyapatite (HAp) were mixed into a polyethylene glycol/silk fibroin (PEG/SF) solution. The amount of HAp ranged from 25 to 100 mg, which provided for different ratios between HAp and the PEG/SF composite. In vitro, the effect of stiffness on the osteogenic differentiation of rat BMSCs was studied. The outcome measures, which were verified in vivo, included the protein expression of runt-related transcription factor 2 and osteocalcin, alkaline phosphatase activity, and the mRNA expression of osteogenesis-related markers. Results: Increasing amounts of HAp resulted in an increased elastic modulus of the cell culture scaffolds. The PEG/SF/HAp fabricated with HAp (50 mg) significantly increased cell adhesion and viability (p < 0.05) as well as the expression of all the osteogenesis-related markers (p < 0.05). Conclusions: We developed a novel cell culture scaffold and demonstrated that substrate stiffness influenced the osteogenic differentiation of rat BMSCs.

We demonstrate a passively mode-locked all-fiber laser generating cylindrical vector beams (CVBs) only using a symmetric two-mode fiber optical coupler (TMF-OC) for both high-order mode excitation and splitting. Theoretical analyses show that for a symmetric TMF-OC with appropriate taper diameter, the second-order mode can be excited and coupled into output tap with high purity due to the effective index difference of different modes. Based on the fabricated TMF-OC, the passively mode-locked fiber laser delivers pulsed CVBs at a center wavelength of 1564.4 nm with 3 dB linewidth of 11.2 nm, pulse duration of 2.552 ps, and repetition rate of 3.96 MHz. The purity of both radially and azimuthally polarized beams is estimated to be over 91%. Due to simple fabrication method of the TMF-OC and high purity of the generated CVBs, this mode-locked CVB fiber laser with all-fiber configuration has potential applications in optical trapping, optical communications, material processing, etc.