Alexandre Toshirrico Cardoso Taketa

Dr. Alexandre Toshirrico Cardoso Taketa

orcid

Research Focus & Metrics

Academic Career Length

32Years (1995-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
1 March 1995 in Journal of Natural Products
Verified
Journal Article
Closed access
GGGrace Gosmann
Grace Gosmann
DGDominique Guillaume
Dominique Guillaume
ATAlexandre Toshirrico Cardoso Taketa
Alexandre Toshirrico Cardoso Taketa
ESEloir Paulo Schenkel
Eloir Paulo Schenkel

15 May 2020 in Biomolecules
Verified
Journal Article
Open access
PDF file
Edgar Jesús Delgado NúñezEdgar Jesús Delgado Núñez
Edgar Jesús Delgado Núñez
Alejandro Zamilpa AlvarezAlejandro Zamilpa Alvarez
Alejandro Zamilpa Alvarez
Manasés Gonzalez-CortazarManasés Gonzalez-Cortazar
Manasés Gonzalez-Cortazar
Agustín Olmedo-JuárezAgustín Olmedo-Juárez
Agustín Olmedo-Juárez
ATAlexandre Toshirrico Cardoso Taketa
Alexandre Toshirrico Cardoso Taketa
PGPedro Mendoza de Gives
Pedro Mendoza de Gives
Haemonchus contortus affect small ruminants all over the world. Anthelmintics cause resistance, contamination, and a risk of public health. Prosopis laevigata is a plant used as a home remedy against many diseases in Mexico. This study arose from a preliminary study where a P. laevigata hydroalcoholic extract (Pl-hae) showed anthelmintic activity (aa) against H. contortus. Searching for bioactive compounds (bac) with high aa, the Pl-hae was fractioned obtaining an aqueous (Aq-F) and an ethyl acetate fraction (EtAc-F), and a flavonoid with aa identified as isorhamnetin was obtained from EtAc-F. Both fractions were in vitro assessed by the egg hatch test (eht) and larval mortality (lm) assays. The bac obtained from EtAc-F were characterised by NMR analysis. The highest aa were recorded with EtAc-F, resulting in 100% eht and 80.45% lm at 0.75 and 30 mg/mL, respectively. Alterations in eggs and larvae attributed to isorhamnetin were recorded by environmental scanning electron microscopy, confocal laser scanning and by high-resolution digital-coupled camera. This flavonoid caused 100% eht at 0.07 mg/mL after 48 h and 100% lm at 7.5 mg/mL after 72 h exposure. Isorhamnetin has promising potential as an anthelmintic against sheep haemonchosis.

31 July 1996 in Phytochemistry
Verified
Journal Article
Closed access
KKKatia H. Kraemer
Katia H. Kraemer
ATAlexandre Toshirrico Cardoso Taketa
Alexandre Toshirrico Cardoso Taketa
ESEloir P. Schenkel
Eloir P. Schenkel
GGGrace Gosmann
Grace Gosmann
DGDominique Guillaume
Dominique Guillaume

28 October 2019 in Molecular Biology Reports
Verified
Journal Article
Closed access
PDF file
OCOlga Lidia Cruz-Miranda
Olga Lidia Cruz-Miranda
JFJorge Folch-Mallol
Jorge Folch-Mallol
FMFernando Martínez-Morales
Fernando Martínez-Morales
RGReinier Gesto-Borroto
Reinier Gesto-Borroto
MVMaria Luisa Villarreal
Maria Luisa Villarreal
ATAlexandre Toshirrico Cardoso Taketa
Alexandre Toshirrico Cardoso Taketa

15 November 2018 in Molecules
Verified
Journal Article
Open access
PDF file
Ashutosh SharmaAshutosh Sharma
Ashutosh Sharma
Paola Isabel Angulo-BejaranoPaola Isabel Angulo-Bejarano
Paola Isabel Angulo-Bejarano
AMAlfredo Madariaga
Alfredo Madariaga
Goldie H. OzaGoldie H. Oza
Goldie H. Oza
Hafiz M. N. IqbalHafiz M. N. Iqbal
Hafiz M. N. Iqbal
MVMaria Luisa Villarreal
Maria Luisa Villarreal
Galphimia glauca (Cav.) Kuntze is an important endemic plant species, which possesses many medicinal properties and has been used in the Mexican traditional medicine for its sedative, anxiolytic, anticonvulsant, antiasthmatic and antiallergic properties. The therapeutic properties of this plant are mainly due to the presence of diverse bioactive compounds such as flavonoids, triterpenoids, and phenolics. Several triterpenoids and flavonoids compounds have been isolated and identified. Modern studies have demonstrated many biological activities such as anti-inflammatory, antidiarrheal, gastroenteritis, antimalarial and cytotoxic activities. Nevertheless, many studies are restricted to the crude extract, and many bioactive compounds are yet to be identified and validated according to its traditional use. However, its commercial exploitation and use are highly limited due to the non-availability of enough plant material and lack of knowledge about its agronomical practices. Moreover, the misinterpretation and mislabeling of closely related species of the genus Galphimia Cav. as G. glauca or G. gracilis is a common problem for its rigorous scientific study and commercial exploitation. The present review provides comprehensive knowledge based on the available scientific literature. To the best of our knowledge, this is the first review on G. glauca. This comprehensive information will certainly provide a guide for the better understanding and utilization of G. glauca for its scientific and industrial exploitation.

1 June 2019 in Journal of Ethnopharmacology
Verified
Journal Article
Closed access
MFMagdala Zulema Figueroa-Suárez
Magdala Zulema Figueroa-Suárez
Judith Gonzalez ChristenJudith Gonzalez Christen
Judith Gonzalez Christen
ATAlexandre Toshirrico Cardoso Taketa
Alexandre Toshirrico Cardoso Taketa
MVMaría del Carmen Gutiérrez Villafuerte
María del Carmen Gutiérrez Villafuerte
Veronica RodriguezVeronica Rodriguez
Veronica Rodriguez