The magnetoencephalogram (MEG) based on array optically pumped magnetometers (OPMs) has the potential of replacing conventional cryogenic superconducting quantum interference device. Phase synchronization is a common method for measuring brain oscillations and functional connectivity. Verifying the feasibility and fidelity of OPM-MEG in measuring phase synchronization will help its widespread application in the study of aforementioned neural mechanisms. The analysis method on source-level time series can weaken the influence of instantaneous field spread effect. In this paper, the OPM-MEG was used for measuring the evoked responses of 20Hz rhythmic and arrhythmic median nerve stimulation, and the inter-trial phase synchronization (ITPS) and inter-reginal phase synchronization (IRPS) of primary somatosensory cortex (SI) and secondary somatosensory cortex (SII) were analysed. The results find that under rhythmic condition, the evoked responses of SI and SII show continuous oscillations and the effect of resetting phase. The values of ITPS and IRPS significantly increase at the stimulation frequency of 20Hz and its harmonic of 40Hz, whereas the arrhythmic stimulation does not exhibit this phenomenon. Moreover, in the initial stage of stimulation, the ITPS and IRPS values are significantly higher at Mu rhythm in the rhythmic condition compared to arrhythmic. In conclusion, the results demonstrate the ability of OPM-MEG in measuring phase pattern and functional connectivity on source-level, and may also prove beneficial for the study on the mechanism of rhythmic stimulation therapy for rehabilitation.

Magnetoencephalography (MEG) is a noninvasive brain imaging technique that investigates dynamic brain changes by measuring magnetic fields generated by neural activities. Recently, significant advancements have been made in Optically Pumped Magnetometer-based Magnetoencephalography (OPM-MEG). Compared with conventional superconducting quantum interference device-based MEG, OPM-MEGs operate at room temperature, reducing costs and allowing more flexible sensor configurations. Most importantly, OPM-MEG allows for meas-urements during natural head movements, facilitating more nat-uralistic experiments and broader applications, including studies involving motor tasks and populations, such as young children or patients with movement disorders. However, motion-compatible OPM-MEGs face significant challenges because of the severe impact of motion artifacts on data quality. This study introduced a Dynamic Background Field Adaptive Filtering method (DBFAF) to suppress motion artifacts in OPM-MEG. The OPM-MEG data were processed by adaptively filtering out the motion artifacts measured using multiple orthogonally oriented OPM reference sensors fixed to a helmet. The simulation results demonstrate that the DBFAF method significantly improves data quality by effectively mitigating the impact of motion artifacts, surpassing the widely used moving-window regression methods. The efficacy and reliability of this method were further verified using median nerve stimulation in OPM-MEG experiments. This approach offers a novel solution for applying OPM-MEG in contexts involving participants’ head movements.

Accurate defect detection of photovoltaic (PV) cells is critical for ensuring quality and efficiency in intelligent PV manufacturing systems. However, the scarcity of rich defect data poses substantial challenges for effective model training. While existing methods have explored generative models to augment datasets, they often suffer from instability, limited diversity, and domain shifts. To address these issues, we propose PDIG, a Photovoltaic Defect Image Generator based on Stable Diffusion (SD). PDIG leverages the strong priors learned from large-scale datasets to enhance generation quality under limited data. Specifically, we introduce a Semantic Concept Embedding (SCE) module that incorporates text-conditioned priors to capture the relational concepts between defect types and their appearances. To further enrich the domain distribution, we design a Lightweight Industrial Style Adaptor (LISA), which injects industrial defect characteristics into the SD model through cross-disentangled attention. At inference, we propose a Text-Image Dual-Space Constraints (TIDSC) module, enforcing the quality of generated images via positional consistency and spatial smoothing alignment. Extensive experiments demonstrate that PDIG achieves superior realism and diversity compared to state-of-the-art methods. Specifically, our approach improves Frechet Inception Distance (FID) by 19.16 points over the second-best method and significantly enhances the performance of downstream defect detection tasks.

Optically pumped magnetometer OPM-MEG has the potential to replace the traditional low-temperature superconducting quantum interference device SQUID-MEG. Coherence analysis can be used to evaluate the functional connectivity and reflect the information transfer process between brain regions. In this paper, a finger tapping movement paradigm based on auditory cues was used to measure the functional signals of the brain using OPM-MEG, and the coherence between the primary motor cortex (M1) and the primary motor area (PM) was calculated and analyzed. The results demonstrated that the coherence of the three frequency bands of Alpha (8–13 Hz), Beta (13–30 Hz), and low Gamma (30–45 Hz) and the selected reference signal showed roughly the same position, the coherence strength and coherence range decreased from Alpha to low Gamma, and the coherence coefficient changed with time. It was inferred that the change in coherence indicated different neural patterns in the contralateral motor cortex, and these neural patterns also changed with time, thus reflecting the changes in the connection between different functional areas in the time-frequency domain. In summary, OPM-MEG has the ability to measure brain coherence during finger movements and can characterize connectivity between brain regions.

The high spatiotemporal resolution of optically pumped magnetometers (OPMs) makes them an essential tool for functional brain imaging, enabling accurate recordings of neuronal activity. However, physiological signals such as eye blinks and cardiac activity overlap with neural magnetic signals in the frequency domain, resulting in contamination and creating challenges for the observation of brain activity and the study of neurological disorders. To address this problem, an automatic physiological artifact removal method based on OPM magnetic reference signals and a channel attention mechanism is proposed. The randomized dependence coefficient (RDC) is employed to evaluate the correlation between independent components and reference signals, enabling reliable recognition of artifact components and the construction of training and testing datasets. A channel attention mechanism is subsequently introduced, which fuses features from global average pooling (GAP) and global max pooling (GMP) layers through convolution to establish a data-driven automatic recognition model. The backbone network is further optimized to enhance performance. Experimental results demonstrate a strong correlation between the magnetic reference signals and artifact components, confirming the reliability of magnetic signals as artifact references for OPM-MEG. The proposed model achieves an artifact recognition accuracy of 98.52% and a macro-average score of 98.15%. After artifact removal, both the event-related field (ERF) responses and the signal-to-noise ratio (SNR) are significantly improved. Leveraging the flexible and modular characteristics of OPM-MEG, this study introduces an artifact recognition framework that integrates magnetic reference signals with an attention mechanism. This approach enables highly accurate automatic recognition and removal of OPM-MEG artifacts, paving the way for real-time, automated data analysis in both scientific research and clinical applications.

Optically pumped magnetometer magnetoencephalography (OPM-MEG) represents a novel method for recording neural signals in the brain, offering the potential to measure critical neuroimaging characteristics such as effective brain networks. Effective brain networks describe the causal relationships and information flow between brain regions. In constructing effective brain networks using Granger causality, the noise in the multivariate autoregressive model (MVAR) is typically assumed to follow a Gaussian distribution. However, in experimental measurements, the statistical characteristics of noise are difficult to ascertain. In this paper, a Granger causality method based on a cost-reference particle filter (CRPF) is proposed for constructing effective brain networks under unknown noise conditions. Simulation results show that the average estimation errors of the MVAR model coefficients using the CRPF method are reduced by 53.4% and 82.4% compared to the Kalman filter (KF) and maximum correntropy filter (MCF) under Gaussian noise, respectively. The CRPF method reduces the average estimation errors by 88.1% and 85.8% compared to the MCF under alpha-stable distribution noise and the KF method under pink noise conditions, respectively. In an experiment, the CRPF method recoversthe latent characteristics of effective connectivity of benchmark somatosensory stimulation data in rats, human finger movement, and auditory oddball paradigms measured using OPM-MEG, which is in excellent agreement with known physiology. The simulation and experimental results demonstrate the effectiveness of the proposed algorithm and OPM-MEG for measuring effective brain networks.