Stromboli volcano (Aeolian Arc, Italy) experiences many mass failures along the Sciara del Fuoco (SdF) scar, which frequently trigger tsunamis of various sizes. In this work, we simulate tsunami waves generated by landslides occurring in the SdF through numerical simulations carried out in two steps: (i) the tsunami triggering, wave propagation and the effects on Stromboli are simulated using the 3D non-hydrostatic model NHWAVE; (ii) generated train waves are then input into the 2D Boussinesq model FUNWAVE-TVD to simulate wave propagation in the Southern Tyrrhenian Sea (STS). We simulated the following scenarios: (i) the tsunami runup, inland inundation and wave propagation at Stromboli triggered by submarine landslides with volumes of 7.1, 11.8, 17.6 and 23.5 × 10⁶ m³ and subaerial landslides with volumes of 4.7, 7.1, 11.8 and 35.3 × 10⁶ m³; (ii) tsunami propagation in the STS triggered by submarine landslides with volumes of 11.8 and 17.6 × 10⁶ m³ and by subaerial landslides with volumes of 7.1 and 35.3 × 10⁶ m³. We estimate that the damages of the last relevant tsunami at Stromboli, which occurred in 2002, could have been generated either by a subaqueous failure of about 17.6-23.5 × 10⁶ m³ along the SdF or/and a subaerial failure of about 4.7-7.1 × 10⁶ m³. The coasts most affected by this phenomenon are not necessarily located near the failure, because the bathymetry and topography can dramatically increase the waves heights locally. Tsunami waves are able to reach the first Stromboli populated beaches in just over 1 minute and the harbour in less than 7 minutes. After about 30 minutes the whole Aeolian Arc would be impacted by maximum tsunami waves. After 1 hour and 20 minutes, waves would encompass the whole STS arriving at Capri.