L.W.D. van Raamsdonk

L.W.D. van Raamsdonk


Research Focus & Metrics

Academic Career Length

35Years (1992-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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9 January 2020 in Foods
Verified
Journal Article
Open access
PDF file
LRL.W.D. van Raamsdonk
L.W.D. van Raamsdonk
MZMeike van der Zande
Meike van der Zande
AKAlbert Koelmans
Albert Koelmans
RHRon Hoogenboom
Ron Hoogenboom
RPRuud Peters
Ruud Peters
YWYannick Weesepoel
Yannick Weesepoel
Microplastics (MPs) are considered an emerging issue as environmental pollutants and a potential health threat. This review will focus on recently published data on concentrations in food, possible effects, and monitoring methods. Some data are available on concentrations in seafood (fish, bivalves, and shrimps), water, sugar, salt, and honey, but are lacking for other foods. Bottled water is a considerable source with numbers varying between 2600 and 6300 MPs per liter. Particle size distributions have revealed an abundance of particles smaller than 25 µm, which are considered to have the highest probability to pass the intestinal border and to enter the systemic circulation of mammals. Some studies with mice and zebrafish with short- or medium-term exposure (up to 42 days) have revealed diverse results with respect to both the type and extent of effects. Most notable modifications have been observed in gut microbiota, lipid metabolism, and oxidative stress. The principal elements of MP monitoring in food are sample preparation, detection, and identification. Identified data gaps include a lack of occurrence data in plant- and animal-derived food, a need for more data on possible effects of different types of microplastics, a lack of in silico models, a lack of harmonized monitoring methods, and a further development of quality assurance.

1 December 2008 in Journal of Food Protection
Verified
Journal Article
Closed access
EFEelco Franz
Eelco Franz
PRPaul Römkens
Paul Römkens
LRL.W.D. van Raamsdonk
L.W.D. van Raamsdonk
Ine Van Der Fels-KlerxIne Van Der Fels-Klerx
Ine Van Der Fels-Klerx
Cadmium in soil poses a risk for human health, due to its accumulation in food and feed crops. The extent of accumulation depends strongly on soil type and the degree of pollution. The objective of...


1 February 2007 in Animal Feed Science and Technology
Verified
Journal Article
Closed access
LRL.W.D. van Raamsdonk
L.W.D. van Raamsdonk
CHChristoph Von Holst
Christoph Von Holst
VBV. Baeten
V. Baeten
GBGilbert Berben
Gilbert Berben
ABA. Boix
A. Boix
JJJ. de Jong
J. de Jong

1 May 2016 in Journal of Veterinary Internal Medicine
Verified
Journal Article
Open access
PDF file
CWCornelie Martine Westermann
Cornelie Martine Westermann
RLR. van Leeuwen
R. van Leeuwen
LRL.W.D. van Raamsdonk
L.W.D. van Raamsdonk
HMHans Mol
Hans Mol
Background: Atypical myopathy (AM) in horses is caused by the plant toxin hypoglycin A, which in Europe typically is found in the sycamore maple tree (Acer pseudoplatanus). Owners are concerned about whether their horses are in danger if they graze near maple trees. Hypothesis/Objectives: To measure hypoglycin A in the most common maple tree species in the Netherlands, and to determine whether concentration of toxin is a predictor of AM in horses. Methods: A total of 278 samples of maple tree leaves, sprouts, and seeds were classified by species. Mean concentrations of hypoglycin A were compared for the type of sample, the season and the occurrence of AM in the pasture (non-AM versus AM). Statistical analysis was performed using generalized a linear model (SPPS22). Results: Almost all Acer pseudoplatanus samples contained hypoglycin A, with concentrations differing significantly among sources (P < .001). Concentrations were significantly higher in seeds from the AM group than in seeds from the non-AM group (856 ± 677 and 456 ± 358 mg/kg, respectively; P = .039). In sprouts and leaves this was not the case. Acer platanoides and Acer campestre samples did not contain detectable concentrations of hypoglycin A. Conclusions and clinical importance: Acer platanoides and campestre seem to be safe around paddocks and pastures, whereas almost all Acer pseudoplatanus samples contained hypoglycin A. In all AM cases, Acer pseudoplatanus was found. Despite significantly higher concentration of hypoglycin A in seeds of pastures where AM has occurred, individual prediction of AM cannot be made by measuring these concentrations because of the high standard deviation.

25 June 2003 in Theoretical and Applied Genetics
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Journal Article
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LRL.W.D. van Raamsdonk
L.W.D. van Raamsdonk
WEW. Ensink
W. Ensink
AHA. W. van Heusden
A. W. van Heusden
MGM. Vrielink-Van Ginkel
M. Vrielink-Van Ginkel
CKC. Kik
C. Kik