The aim of this study was to conduct a bibliometric analysis of the scientific articles on advanced glycation end products (AGEs) and obesity. English-language journal articles about AGEs and obesity were retrieved from the Scopus database. The OpenRefine application was used for data cleaning, the VOSviewer software program for analysis of the trends of year of publication, country, institution, journal, authors, references, and keywords. Microsoft Excel and Tableau Public were applied for the visualizing of the publication trends. Data collection was performed on 3 February 2022, from a total of 1170 documents. The Mann–Whitney test and Spearman test with software SPSS ver.28.0.1.1. were used to assess the relation between open access journal statuses, years of publications, and CiteScore. The results of the study showed that there was an increase in studies on processed foods, including AGEs and obesity. The United States was the country with the largest contribution in this field, with the highest number of citations. The Nutrients journal published the largest number of articles on this topic, particularly in the last two years. The present focus of the studies is on ultra-processed foods. The open access journals have younger medians of the year of publication and higher medians for number of citations than do closed access journals (p < 0.001 and p < 0.05, respectively). A strong negative association was seen between CiteScore and the year of publication (r = −0.64 [95% CI: −0.67, −0.60]), p < 0.001. We present this bibliometric analysis to furnish the most recent data on the description, visualization, and analysis of AGEs and obesity.

Dietary and plasma carboxymethyl lysine (dCML, pCML) and plasma tumor necrosis factor-α (pTNF-α) may be associated with obesity in affluent society. However, evidence in women from low-middle income countries with predominantly traditional diets is lacking. We investigated the mediator effects of dCML, pCML and pTNF-α on body mass index (BMI) and waist circumference (WC) among Indonesian women. A cross-sectional study was conducted among 235 non-diabetic, non-anemic and non-smoking women aged 19–50 years from selected mountainous and coastal areas of West Sumatra and West Java. Dietary CML, pCML, pTNF-α were obtained from 2 × 24-h recalls, ultra-performance liquid chromatography-tandem mass spectrometry and enzyme-linked immunosorbent assay, respectively. Between-group differences were analyzed by the Chi-square or Mann-Whitney test and mediator effects by Structural Equation Modeling. The medians and interquartile-ranges of dCML, pCML and pTNF-α were 2.2 (1.7–3.0) mg/day, 22.2 (17.2–28.2) ng/mL and 0.68 (0.52–1.00) IU/mL, respectively, and significantly higher in the WC ≥ 80 cm than in the WC < 80 cm group, but not in BMI ≥ 25 kg/m² compared to BMI < 25 kg/m² group. Plasma CML and pTNF-α were positively and directly related to WC (β = 0.21 [95% CI: 0.09, 0.33] and β = 0.23 [95% CI: 0.11, 0.35], respectively). Dietary CML that correlated with dry-heat processing and cereals as the highest contributions was positively related to WC (β = 0.33 [95% CI: 0.12, 0.83]). Ethnicity, level of education, intake of fat, and intake of energy contributed to dCML, pCML and pTNF-α, and subsequently affected WC, while only ethnicity contributed to BMI through dCML, pCML and pTNF-α (β = 0.07 [95% CI: 0.01, 0.14]). A positive direct effect of dCML on pCML and of pCML and pTNF-α on WC was seen among Indonesian women. Dietary CML seems to have several paths that indirectly influence the increases in WC if compared to BMI. Thus, intake of CML-rich foods should be reduced, or the foods consumed in moderate amounts to avoid the risk of central obesity in this population.

There is little data on directly measured carboxymethyl lysine (CML) content in Indonesian foods. This study aimed to generate a database of CML values in foods commonly consumed in West Java and West Sumatra. The results were to be used to update our previous estimated CML values. CML values in food samples were measured using high-pressure liquid chromatography with tandem mass spectrometry (HPLC-MS/MS). Food protein content was analyzed by Kjeldahl’s method or inferred from the nutrition facts’ label. A total of 210 food samples were examined, with the food groups of meat and poultry (1.06 mg CML/100 g edible food), and starchy foods (0.21 mg/100 g edible food) having the highest and lowest mean CML levels, respectively. We found that the foods with the top three highest CML content were fried starch dough (cimol), fried fish crackers, and chicken gulai. The mean of the estimated values (0.80 mg CML/100 g edible food) was higher than the directly measured values (0.66 mg CML/100 g edible food), [p < 0.035]. Conclusion: This database provides information on CML values in Indonesian foods, and can be further used to make a guide policy for the selection of foods to reduce non-communicable diseases. Further measurements are needed on Indonesian dishes to complete the database.

Octavia L, et al. Pediatr Gastroenterol Hepatol Nutr. 2025 Mar;28(2):135-140. https://doi.org/10.5223/pghn.2025.28.2.135

Stunting and obesity in Indonesia are still unresolved problems This may be caused by a lack of parental knowledge. StResearch regarding increasing parental knowledge about stunting and the use of growth charts is still controversial. This research aims to determine the effectiveness of health education on parental knowledge. This was a one-group experimental pre- and post-test study involving 61 parents of children aged 3-18 years. A modified structured questionnaire was used to assess stunting knowledge scores through seminars and growth chart knowledge scores through mentoring. Data were analyzed using SPSS ver. 29.0.2.0. The Mann-Whitney test was used to compare changes in scores after the seminar and mentoring training. Post-test knowledge score of seminars and mentoring method improved significantly compared with pretest scores (p < 0.001 for both analyses). The increase in scores for the mentoring method was three times compared to the seminar method (p=0.016). The implication of these findings is that mentoring methods can be considered further on a larger community scale for parent capacity building programs to achieve reduction of malnutrition in Indonesia.

Pemantauan pertumbuhan sangat penting dalam deteksi dini gangguan pertumbuhan anak, termasuk stunting. Salah satu penilaian pertumbuhan anak adalah dengan menggunakan kurva pertumbuhan, yang sebaiknya diketahui juga oleh masyarakat, selain para kader, tenaga kesehatan, dan guru. Sebelumnya hampir tidak pernah dilaksanakan pelatihan penggunaan kurva kepada ibu hamil dan ibu dengan anak di bawah dua tahun di Desa Nagrak dan Desa Ciangsana. Karena itu tim pengabdian masyarakat melakukan pelatihan peningkatan keterampilan dan keberdayaan masyarakat dengan metode kegiatan yaitu pelatihan penggunaan kurva pertumbuhan anak untuk menilai status berat dan tinggi badan menurut usia anak. Kegiatan diadakan hari Sabtu, 9 November 2024, pk.08.00–12.00 WIB di Lahan kampus Trisakti, Nagrak, Bogor, Jawa Barat. Terdapat 31 responden yaitu 16 warga Desa Nagrak dan 15 warga Desa Ciangsana. Median (p25–p75) usia responden adalah 29 (25–32) tahun. Hasil PkM menunjukkan mayoritas responden belum mengetahui penggunaan kurva pertumbuhan, sesuai median (p25–p75) skor pengetahuan sebelum pelatihan sebesar 20 (0–50), dan skor meningkat secara sinifikan sebesar lima kali setelah dilakukan pelatihan. Luaran lainnya adalah publikasi media masa dan HKI. Kesimpulan: Kegiatan pengabdian masyarakat ini berhasil meningkatkan pengetahuan masyakarat mengenai penggunaan kurva pertumbuhan. Pelatihan bercakupan lebih luas diperlukan untuk meningkatkan pengetahuan masyakarakat Indonesia, khususnya keluarga risiko stunting.