The improvement of emergency department processes involves the need to take into considerationmultiple variables and objectives in a highly dynamic and unpredictable environment, which makes thedecision-making task extremely challenging. The use of different methodologies and tools to support thedecision-making process is therefore a key issue. This article presents a novel approach in healthcarein which Discrete Event Simulation, Simulation-Based Multi-Objective Optimization and Data Miningtechniques are used in combination. This methodology has been applied for a system improvementanalysis in a Swedish emergency department. As a result of the project, the decision makers were providedwith a range of nearly optimal solutions and design rules which reduce considerably the length of stayand waiting times for emergency department patients. These solutions include the optimal number ofresources and the required level of improvement in key processes. The article presents and discussesthe benefits achieved by applying this methodology, which has proven to be remarkably valuable fordecision-making support, with regard to complex healthcare system design and improvement

Optimizing production systems is urgent and indispensable if companies are to cope with global competition and a move from mass production to mass customization. The urgency of this need is more obvious in old production plants with a history of modifications, expansions, and adaptations in their production facilities. It is common to find complex, intricate and inefficient systems of material and product flows as a result of poor production facility layout. Several approaches can be used to support the design of optimal facility layouts. However, there is a lack of a suitable generic methodology for designing such layouts. Additionally, there has been little focus on the data and resources required, or on how simulation and optimization can support the design of optimal facilities. To overcome these deficiencies, this paper studies the integration of simulation and optimization for the design and improvement of facility layouts taking into account production and logistics constraints. The paper includes a generic perspective and a detailed implementation. The proposed methodology is evaluated in two case studies and by drawing on the principles and tools of the functional resonance analysis method. This method analyzes the implementation order and variability of a group of processes that can lead to unwanted outcomes. The results can provide managers and other stakeholders with a methodology that adequately considers production and logistics constraints when seeking an optimized facility layout design.

Facility layout design is becoming more challenging as manufacturing moves from traditionally emphasised mass production to mass customisation. The increasing demand for customised products and services is driving the need to increase flexibility and adaptability of both production processes and their material handling systems. A holistic approach for designing facility layouts with optimised flows considering production and logistics systems constraints seems to be missing in the literature. Several tools, including traditional methods, analytic hierarchy process, multiple-attribute decision making, simulation, and optimisation methods, can support such a process. Among these, simulation-based optimisation is the most promising. This paper aims to develop a facility layout design methodology supported by simulation-based optimisation while considering both production and logistics constraints. A literature review of facility layout design with simulation and optimisation and the theoretical and empirical challenges are presented. The integration of simulation-based optimisation in the proposed methodology serves to overcome the identified challenges, providing managers and stakeholders with a decision support system that handles the complex task of facility layout design.

The increasing complexity of modern automotive lighting systems requires advanced validation strategies that ensure both functional performance and regulatory compliance. This study presents a structured integration of Software-in-the-Loop (SiL) and Hardware-in-the-Loop (HiL) testing within a digital twin (DT) framework for validating headlamp systems. A gated validation process (G10–G120) is proposed, aligning each development phase with corresponding simulation stages from early requirements and concept validation to real-world scenario testing and continuous integration. A key principle of this approach is the adoption of a framework built upon the V-Cycle, adapted to integrate DT technology with SiL and HiL workflows. This architectural configuration ensures a continuous data flow between the physical system, the digital twin, and embedded software components, enabling real-time feedback, iterative model refinement, and traceable system verification throughout the development lifecycle. The paper also explores strategies for effective DT integration, such as digital twin-as-a-service, which combines virtual testing with physical validation to support earlier fault detection, streamlined simulation workflows, and reduced dependency on physical prototypes during lighting system development. Unlike the existing literature, which often treats SiL, HiL, and DTs in isolation, this work proposes a unified, domain-specific validation framework. The methodology addresses a critical gap by aligning simulation-based testing with development milestones and regulatory standards, offering a foundation for industrial adoption.

Extended reality (XR) technologies are gaining traction in technical education due to their potential for creating immersive and interactive training environments. This study presents the development and empirical evaluation of X-RAPT, a collaborative VR-based platform designed to train students in industrial robotics programming. The system enables multi-user interaction, cross-platform compatibility (VR and PC), and real-time data logging through a modular simulation framework. A pilot evaluation was conducted in a vocational training institute with 15 students performing progressively complex tasks in alternating roles using both VR and PC interfaces. Performance metrics were captured automatically from system logs, while post-task questionnaires assessed usability, comfort, and interaction quality. The findings indicate high user engagement and a distinct learning curve, evidenced by progressively shorter task completion times across levels of increasing complexity. Role-based differences were observed, with main users showing greater interaction frequency but both roles contributing meaningfully. Although hardware demands and institutional constraints limited the scale of the pilot, the findings support the platform’s potential for enhancing robotics education.