This page has only limited features, please log in for full access.

Unclaimed
Vanessa Morais
Departamento de Moléstias Infecciosas e Parasitárias and Instituto de Medicina Tropical da Faculdade de Medicina da Universidade de São Paulo, São Paulo 05403-000, SP, Brazil

Honors and Awards

The user has no records in this section


Career Timeline

The user has no records in this section.


Short Biography

The user biography is not available.
Following
Followers
Co Authors
The list of users this user is following is empty.
Following: 0 users

Feed

Communication
Published: 22 June 2021 in Microorganisms
Reads 0
Downloads 0

Squash mosaic virus (SqMV) is a phytovirus that infects great diversity of plants worldwide. In Brazil, the SqMV has been identified in the states of Ceará, Maranhão, Piauí, Rio Grande do Norte, and Tocantins. The presence of non-pathogenic viruses in animals, such as phytoviruses, may not be completely risk-free. Similarities in gene repertories between these viruses and viruses that affect animal species have been reported. The present study describes the fully sequenced genomes of SqMV found in human feces, collected in Tocantins, and analyzes the viral profile by metagenomics in the context of diarrhea symptomatology. The complete SqMV genome was obtained in 39 of 253 analyzed samples (15.5%); 97.4% of them belonged to children under 5 years old. There was no evidence that the observed symptoms were related to the presence of SqMV. Of the different virus species detected in these fecal samples, at least 4 (rotavirus, sapovirus, norovirus, parechovirus) are widely known to cause gastrointestinal symptoms. The presence of SqMV nucleic acid in fecal samples is likely due to recent dietary consumption and it is not evidence of viral replication in the human intestinal cells. Identifying the presence of SqMV in human feces and characterization of its genome is a relevant precursor to determining whether and how plant viruses interact with host cells or microorganisms in the human gastrointestinal tract.

ACS Style

Fabiola Villanova; Roberta Marcatti; Mayara Bertanhe; Vanessa Morais; Flavio Milagres; Rafael Brustulin; Emerson Araújo; Roozbeh Tahmasebi; Steven Witkin; Xutao Deng; Eric Delwart; Ester Sabino; Cassio Abreu-Junior; Élcio Leal; Antonio Costa. New Variants of Squash Mosaic Viruses Detected in Human Fecal Samples. Microorganisms 2021, 9, 1349 .

AMA Style

Fabiola Villanova, Roberta Marcatti, Mayara Bertanhe, Vanessa Morais, Flavio Milagres, Rafael Brustulin, Emerson Araújo, Roozbeh Tahmasebi, Steven Witkin, Xutao Deng, Eric Delwart, Ester Sabino, Cassio Abreu-Junior, Élcio Leal, Antonio Costa. New Variants of Squash Mosaic Viruses Detected in Human Fecal Samples. Microorganisms. 2021; 9 (7):1349.

Chicago/Turabian Style

Fabiola Villanova; Roberta Marcatti; Mayara Bertanhe; Vanessa Morais; Flavio Milagres; Rafael Brustulin; Emerson Araújo; Roozbeh Tahmasebi; Steven Witkin; Xutao Deng; Eric Delwart; Ester Sabino; Cassio Abreu-Junior; Élcio Leal; Antonio Costa. 2021. "New Variants of Squash Mosaic Viruses Detected in Human Fecal Samples." Microorganisms 9, no. 7: 1349.

Journal article
Published: 16 April 2021 in Viruses
Reads 0
Downloads 0

Dengue virus (DENV) is a mosquito-borne viral pathogen that plagues many tropical-climate nations around the world, including Brazil. Molecular epidemiology is a growing and increasingly invaluable tool for understanding the dispersal, persistence, and diversity of this impactful virus. In this study, plasma samples (n = 824) from individuals with symptoms consistent with an arboviral febrile illness were analyzed to identity the molecular epidemiological dynamics of DENV circulating in the Brazilian state of Amapá. Twelve DENV type 1 (DENV-1) genomes were identified, which were phylogenetically related to the BR4 lineage of genotype V. Phylodynamics analysis suggested that DENV-1 BR-4 was introduced into Amapá around early 2010, possibly from other states in northern Brazil. We also found unique amino acids substitutions in the DENV-1 envelope and NS5 protein sequences in the Amapá isolates. Characterization of the DENV-1 BR-4 sequences highlights the potential of this new lineage to drive outbreaks of dengue in the Amazon region.

ACS Style

Geovani Ribeiro; Danielle Gill; Edcelha Ribeiro; Fred Monteiro; Vanessa Morais; Roberta Marcatti; Marlisson Rego; Emerson Araújo; Steven Witkin; Fabiola Villanova; Xutao Deng; Ester Sabino; Eric Delwart; Élcio Leal; Antonio da Costa. Adaptive Evolution of New Variants of Dengue Virus Serotype 1 Genotype V Circulating in the Brazilian Amazon. Viruses 2021, 13, 689 .

AMA Style

Geovani Ribeiro, Danielle Gill, Edcelha Ribeiro, Fred Monteiro, Vanessa Morais, Roberta Marcatti, Marlisson Rego, Emerson Araújo, Steven Witkin, Fabiola Villanova, Xutao Deng, Ester Sabino, Eric Delwart, Élcio Leal, Antonio da Costa. Adaptive Evolution of New Variants of Dengue Virus Serotype 1 Genotype V Circulating in the Brazilian Amazon. Viruses. 2021; 13 (4):689.

Chicago/Turabian Style

Geovani Ribeiro; Danielle Gill; Edcelha Ribeiro; Fred Monteiro; Vanessa Morais; Roberta Marcatti; Marlisson Rego; Emerson Araújo; Steven Witkin; Fabiola Villanova; Xutao Deng; Ester Sabino; Eric Delwart; Élcio Leal; Antonio da Costa. 2021. "Adaptive Evolution of New Variants of Dengue Virus Serotype 1 Genotype V Circulating in the Brazilian Amazon." Viruses 13, no. 4: 689.

Journal article
Published: 31 March 2021 in Viruses
Reads 0
Downloads 0

Echoviruses (E) are a diverse group of viruses responsible for various pathological conditions in humans including aseptic meningitis, myocarditis, and acute flaccid paralysis. The detection and identification of echovirus genotypes in clinical samples is challenging due to its high genetic diversity. Here, we report the complete genome sequences of nine echoviruses, obtained by next-generation sequencing of 238 fecal samples from individuals with gastroenteritis in regions of Brazil. Detected viruses were classified into six genotypes: Three E1 sequences (BRA/TO-028, BRA/TO-069 and BRA/TO-236), one E3 (BRA/TO-018), one E11 (BRA/TO-086), one E20 (BRA/TO-016), two E29 (BRA/TO-030 and BRA/TO-193), and one E30 sequence (BRA/TO-032). Phylogenetic analysis indicated that the echoviruses E1 and E29 circulating in Brazil are divergent from strains circulating worldwide. The genotype diversity identified in our study may under-represent the total echovirus diversity in Brazil because of the small sample size and the restricted geographical distribution covered by the survey.

ACS Style

Endrya Do Socorro Fôro Ramos; Ulisses Rosa; Geovani De Oliveira Ribeiro; Fabiola Villanova; Flávio de Pádua Milagres; Rafael Brustulin; Vanessa Dos Santos Morais; Mayara Bertanhe; Roberta Marcatti; Emerson Araújo; Steven Witkin; Eric Delwart; Adriana Luchs; Antonio da Costa; Élcio Leal. High Heterogeneity of Echoviruses in Brazilian Children with Acute Gastroenteritis. Viruses 2021, 13, 595 .

AMA Style

Endrya Do Socorro Fôro Ramos, Ulisses Rosa, Geovani De Oliveira Ribeiro, Fabiola Villanova, Flávio de Pádua Milagres, Rafael Brustulin, Vanessa Dos Santos Morais, Mayara Bertanhe, Roberta Marcatti, Emerson Araújo, Steven Witkin, Eric Delwart, Adriana Luchs, Antonio da Costa, Élcio Leal. High Heterogeneity of Echoviruses in Brazilian Children with Acute Gastroenteritis. Viruses. 2021; 13 (4):595.

Chicago/Turabian Style

Endrya Do Socorro Fôro Ramos; Ulisses Rosa; Geovani De Oliveira Ribeiro; Fabiola Villanova; Flávio de Pádua Milagres; Rafael Brustulin; Vanessa Dos Santos Morais; Mayara Bertanhe; Roberta Marcatti; Emerson Araújo; Steven Witkin; Eric Delwart; Adriana Luchs; Antonio da Costa; Élcio Leal. 2021. "High Heterogeneity of Echoviruses in Brazilian Children with Acute Gastroenteritis." Viruses 13, no. 4: 595.

Journal article
Published: 01 December 2020 in Journal of General Virology
Reads 0
Downloads 0

Human enteric adenovirus species F (HAdV-F) is one of the most common pathogens responsible for acute gastroenteritis worldwide. Brazil is a country with continental dimensions where continuous multiregional surveillance is vital to establish a more complete picture of the epidemiology of HAdV-F. The aim of the current study was to investigate the molecular epidemiology of HAdV-F using full-genome data in rural and low-income urban areas in northern Brazil. This will allow a genetic comparison between Brazilian and global HAdV-F strains. The frequency of HAdV-F infections in patients with gastroenteritis and molecular typing of positive samples within this period was also analysed. A total of 251 stool samples collected between 2010 and 2016 from patients with acute gastroenteritis were screened for HAdV-F using next-generation sequencing techniques. HAdV-F infection was detected in 57.8 % (145/251) of samples. A total of 137 positive samples belonged to HAdV-F41 and 7 to HAdV-F40. HAdV-F40/41 dual infection was found in one sample. Detection rates did not vary significantly according to the year. Single HAdV-F infections were detected in 21.9 % (55/251) of samples and mixed infections in 37.4 % (94/251), with RVA/HAdV-F being the most frequent association (21.5 %; 54/251). Genetic analysis indicated that the HAdV-F strains circulating in Brazil were closely related to worldwide strains, and the existence of some temporal order was not observed. This is the first large-scale HAdV-F study in Brazil in which whole-genome data and DNA sequence analyses were used to characterize HAdV-F strains. Expanding the viral genome database could improve overall genotyping success and assist the National Center for Biotechnology Information (NCBI)/GenBank in standardizing the HAdV genome records by providing a large set of annotated HAdV-F genomes.

ACS Style

Roozbeh Tahmasebi; Adriana Luchs; Kaelan Tardy; Philip Michael Hefford; Rory J. Tinker; Owrang Eilami; Flavio Augusto De Padua Milagres; Rafael Brustulin; Maria Da Aparecida Rodrigues Teles; Vanessa Dos Santos Morais; Carlos Henrique Valente Moreira; Renata Buccheri; Emerson Luiz Lima Araújo; Fabiola Villanova; Xutao Deng; Ester Cerdeira Sabino; Eric Delwart; Élcio Leal; Antonio Charlys Da Costa. Viral gastroenteritis in Tocantins, Brazil: characterizing the diversity of human adenovirus F through next-generation sequencing and bioinformatics. Journal of General Virology 2020, 101, 1280 -1288.

AMA Style

Roozbeh Tahmasebi, Adriana Luchs, Kaelan Tardy, Philip Michael Hefford, Rory J. Tinker, Owrang Eilami, Flavio Augusto De Padua Milagres, Rafael Brustulin, Maria Da Aparecida Rodrigues Teles, Vanessa Dos Santos Morais, Carlos Henrique Valente Moreira, Renata Buccheri, Emerson Luiz Lima Araújo, Fabiola Villanova, Xutao Deng, Ester Cerdeira Sabino, Eric Delwart, Élcio Leal, Antonio Charlys Da Costa. Viral gastroenteritis in Tocantins, Brazil: characterizing the diversity of human adenovirus F through next-generation sequencing and bioinformatics. Journal of General Virology. 2020; 101 (12):1280-1288.

Chicago/Turabian Style

Roozbeh Tahmasebi; Adriana Luchs; Kaelan Tardy; Philip Michael Hefford; Rory J. Tinker; Owrang Eilami; Flavio Augusto De Padua Milagres; Rafael Brustulin; Maria Da Aparecida Rodrigues Teles; Vanessa Dos Santos Morais; Carlos Henrique Valente Moreira; Renata Buccheri; Emerson Luiz Lima Araújo; Fabiola Villanova; Xutao Deng; Ester Cerdeira Sabino; Eric Delwart; Élcio Leal; Antonio Charlys Da Costa. 2020. "Viral gastroenteritis in Tocantins, Brazil: characterizing the diversity of human adenovirus F through next-generation sequencing and bioinformatics." Journal of General Virology 101, no. 12: 1280-1288.

Journal article
Published: 08 August 2020 in Viruses
Reads 0
Downloads 0

Viruses are the most diverse and abundant microorganisms on earth, highly adaptive to a wide range of hosts. Viral diversity within invertebrate hosts has gained notoriety in recent years in public health as several such viruses have been of medical importance. Aedes aegypti serves as a vector for several viruses that have caused epidemics within the last year throughout Brazil; including Dengue, Zika and Chikungunya. This study aimed to identify new viral agents within Aedes aegypti mosquito in a city of the Amazonian region, where it is highly endemic. Metagenomic investigation was performed on 60 mosquito pools and viral RNA sequences present in their microbiota were characterized using genomic and phylogenetic tools. In total, we identified five putative novel virus species related to the Sobemovirus genus, Iflavirus genus and Permutatetraviridae family. These findings indicate a diverse taxonomy of viruses present in the mosquito microbiota of the Amazon, the region with the greatest invertebrate diversity in the world.

ACS Style

Geovani De Oliveira Ribeiro; Vanessa S. Morais; Fred Julio Costa Monteiro; Edcelha Soares D’Athaide Ribeiro; Marlisson Octavio Da S Rego; Raimundo Nonato Picanço Souto; Fabiola Villanova; Roozbeh Tahmasebi; Philip Michael Hefford; Xutao Deng; Eric Delwart; Ester Cerdeira Sabino; Licia Natal Fernandes; Antonio Charlys Da Costa; Élcio Leal. Aedes aegypti from Amazon Basin Harbor High Diversity of Novel Viral Species. Viruses 2020, 12, 866 .

AMA Style

Geovani De Oliveira Ribeiro, Vanessa S. Morais, Fred Julio Costa Monteiro, Edcelha Soares D’Athaide Ribeiro, Marlisson Octavio Da S Rego, Raimundo Nonato Picanço Souto, Fabiola Villanova, Roozbeh Tahmasebi, Philip Michael Hefford, Xutao Deng, Eric Delwart, Ester Cerdeira Sabino, Licia Natal Fernandes, Antonio Charlys Da Costa, Élcio Leal. Aedes aegypti from Amazon Basin Harbor High Diversity of Novel Viral Species. Viruses. 2020; 12 (8):866.

Chicago/Turabian Style

Geovani De Oliveira Ribeiro; Vanessa S. Morais; Fred Julio Costa Monteiro; Edcelha Soares D’Athaide Ribeiro; Marlisson Octavio Da S Rego; Raimundo Nonato Picanço Souto; Fabiola Villanova; Roozbeh Tahmasebi; Philip Michael Hefford; Xutao Deng; Eric Delwart; Ester Cerdeira Sabino; Licia Natal Fernandes; Antonio Charlys Da Costa; Élcio Leal. 2020. "Aedes aegypti from Amazon Basin Harbor High Diversity of Novel Viral Species." Viruses 12, no. 8: 866.

Case reports
Published: 04 April 2018 in The American Journal of Tropical Medicine and Hygiene
Reads 0
Downloads 0

Negative results in serological routine screening of patients with microbiologically proven PCM are occasionally reported. Failure in detecting anti-Paracoccidioides antibodies has been ascribed to factors either related to serological techniques or to the status of the host immune reactivity. Recently, this issue has been renewed by the recognition that the Paracoccidioides genera comprises two species, lutzii and brasiliensis, which have distinct antigenic profiles and, therefore, may elicit different host antibody responses. We describe a patient with the acute form PCM due to Paracoccidioides brasiliensis with negative results on two reference centers’ routine screening for P. brasiliensis antibodies, but positive results with Paracoccidioides lutzii antigens. The present case report suggests that antibodies elicited during P. brasiliensis infection recognize antigenic fractions shared by both species, highlighting the difficulties in distinguishing the two infections by means of the currently available routine serological assays.

ACS Style

Renata Buccheri; Mónica Scarpelli Martinelli Vidal; Vanessa Dos Santos Moraes; Gabriel Naves; Camila Mika Kamikawa; Adriana Pardini Vicentini; Gil Benard; Gilda Maria Barbaro Del Negro. Case Report: Misleading Serological Diagnosis of Paracoccidioidomycosis in a Young Patient with the Acute Form Disease: Paracoccidioides brasiliensis or Paracoccidioides lutzii? The American Journal of Tropical Medicine and Hygiene 2018, 98, 1082 -1085.

AMA Style

Renata Buccheri, Mónica Scarpelli Martinelli Vidal, Vanessa Dos Santos Moraes, Gabriel Naves, Camila Mika Kamikawa, Adriana Pardini Vicentini, Gil Benard, Gilda Maria Barbaro Del Negro. Case Report: Misleading Serological Diagnosis of Paracoccidioidomycosis in a Young Patient with the Acute Form Disease: Paracoccidioides brasiliensis or Paracoccidioides lutzii? The American Journal of Tropical Medicine and Hygiene. 2018; 98 (4):1082-1085.

Chicago/Turabian Style

Renata Buccheri; Mónica Scarpelli Martinelli Vidal; Vanessa Dos Santos Moraes; Gabriel Naves; Camila Mika Kamikawa; Adriana Pardini Vicentini; Gil Benard; Gilda Maria Barbaro Del Negro. 2018. "Case Report: Misleading Serological Diagnosis of Paracoccidioidomycosis in a Young Patient with the Acute Form Disease: Paracoccidioides brasiliensis or Paracoccidioides lutzii?" The American Journal of Tropical Medicine and Hygiene 98, no. 4: 1082-1085.