Carina Sonia Neagu

Dr. Carina Sonia Neagu

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Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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4 April 2024 in Polymers
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Journal Article
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ANANDREEA CODRUTA NOVAC
ANDREEA CODRUTA NOVAC
ATAnca Tudor
Anca Tudor
DPDaniela Maria Pop
Daniela Maria Pop
CNCarina-Sonia Neagu
Carina-Sonia Neagu
Emanuela Lidia PetrescuEmanuela Lidia Petrescu
Emanuela Lidia Petrescu
Cosmin SinescuCosmin Sinescu
Cosmin Sinescu
The impression materials utilized today in dental medicine offer a good reproducibility and are easily accepted by patients. However, because they are polymer-based, they have issues regarding their dimensional stability. In this respect, the present work proposes a new type of dental impression, which is reinforced with rigid mouthguards. The aim of the study is to test the performances of such new impressions by comparing them to conventional ones—from this critical point of view, of the dimensional stability. Three types of polymeric materials were considered for both types of impressions: alginate, condensation silicone, and addition silicone. In order to obtain the new type of impressions, a manufacturing technique was developed, comprising the following phases: (i) conventional impressions were made; (ii) a plaster model was duplicated, and 15 rigid mouthguards were obtained; (iii) they were inserted in the impression technique, with each mouthguard positioned on the cast before the high-consistency material was inserted in the tray and the practitioner took the impression; (iv) the mouthguard remained in the tray and the low-viscosity material was inserted over the mouthguard; (v) the impression was positioned on the model, and after the material hardened, the mouthguard-reinforced impression was analyzed. In the evaluation of the dimensional stability, rigorous statistical analysis was essential to discern the performance differences between conventional and mouthguard-reinforced dental impressions. Statistical analyses employed non-parametric Mann–Whitney U tests because of the non-normal distribution of the data. They indicated a statistically significant improvement in the dimensional stability of addition silicone impressions when reinforced with mouthguards (p < 0.05), showcasing superior performance over conventional methods. Conversely, alginate and condensation silicone reinforced impressions did not exhibit the same level of stability improvement, suggesting the need for further optimization of these materials. In conclusion, from the three considered elastomers, addition silicone was found to be the prime candidate for high-precision dental impressions, with the potential to improve their quality from conventional impressions by utilizing the proposed reinforcing technique.

17 July 2025 in Medicina
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CNCarina-Sonia Neagu
Carina-Sonia Neagu
ANANDREEA CODRUTA NOVAC
ANDREEA CODRUTA NOVAC
CZCristian Zaharia
Cristian Zaharia
Meda-Lavinia NegrutiuMeda-Lavinia Negrutiu
Meda-Lavinia Negrutiu
Izabella CraciunescuIzabella Craciunescu
Izabella Craciunescu
Cosmin SinescuCosmin Sinescu
Cosmin Sinescu
Background and Objectives: Dental adhesives augmented with magnetic nanoparticles (MNPs) have been proposed to prevent microleakages. MNPs dispersed in a dental adhesive reduce the thickness of the adhesive layer applied in a magnetic field and enhance the bond strength by favoring the penetration of the adhesive into dentinal tubules. However, the restoration’s color has been found to be affected by the MNPs. This study tests the hypothesis that MNP coating can alleviate the esthetic impact of magnetic dental adhesives. Materials and Methods: We synthesized Fe3O4 MNPs with silica coating (MNPs-SiO2), calcium-based coating (MNPs-Ca), and no coating. Their morphology was studied using transmission electron microscopy (TEM) and scanning electron microscopy (SEM). Their chemical composition was assessed by energy-dispersive X-ray spectroscopy (EDX), and magnetic properties were measured using a vibrating sample magnetometer. FTIR spectroscopy was used to evaluate the polymerization of the MNP-laden adhesive. We prepared cavities in molar phantoms divided in four groups (n = 15 each) restored using the same adhesive with different MNP contents: Group 0 (G0)—no MNPs, G1—MNPs-SiO2, G2—MNPs-Ca, and G3—uncoated MNPs. The restoration’s color was quantified in the CIELAB color space using a dental spectrophotometer. Results: MNPs-SiO2 were globular, whereas MNPs-Ca had a cubic morphology. The SiO2 layer was 73.1 nm ± 9.9 nm thick; the Ca(OH)2 layer was 19.97 nm ± 2.27 nm thick. The saturation magnetization was 18.6 emu/g for MNPs-SiO2, 1.0 emu/g for MNPs-Ca, and 65.7 emu/g for uncoated MNPs. MNPs had a marginal effect on the adhesive’s photopolymerization. The mean color difference between G0 and G2 was close to the 50:50% acceptability threshold, whereas the other groups were far apart from G0. The mean whiteness index of G2 did not differ significantly from that of G0; G1 deviated marginally from G0, whereas G3 differed significantly from G0. Conclusions: These results suggest that MNP coating can mitigate the influence of MNP-laden dental adhesives on the color of restorations.

27 October 2025 in Proceedings
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CNCarina-Sonia Neagu
Carina-Sonia Neagu
RTRobert Angelo Tuce
Robert Angelo Tuce
Rodica TurcuRodica Turcu
Rodica Turcu
Izabella CraciunescuIzabella Craciunescu
Izabella Craciunescu
VSVlad Mircea Socoliuc
Vlad Mircea Socoliuc
Cosmin SinescuCosmin Sinescu
Cosmin Sinescu
Recent advancements in dental adhesive technology have demonstrated the significant benefits of incorporating magnetic nanoparticles (MNPs) into resin adhesives

29 August 2025 in Journal of Clinical Medicine
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RNRoxana Talpos Niculescu
Roxana Talpos Niculescu
Ioana VejaIoana Veja
Ioana Veja
CNCarina-Sonia Neagu
Carina-Sonia Neagu
Laura-Cristina RusuLaura-Cristina Rusu
Laura-Cristina Rusu
STSerban Talpos
Serban Talpos
LNLuminita Maria Nica
Luminita Maria Nica
Background: Large periapical cyst-like lesions pose challenges for nonsurgical management. This study evaluated the clinical and radiological outcomes of conventional endodontic therapy alone versus endodontic therapy with decompression in treating such lesions. Methods: Ten patients with CBCT-confirmed periapical lesions >5 mm were randomly assigned to two groups. Group 1 received standard root canal treatment with calcium hydroxide; Group 2 received the same protocol plus decompression. Lesion dimensions were measured in three planes using CBCT at baseline, 12 months, and 24 months. Results: Both groups showed significant lesion size reduction over time. At 12 months, Group 2 had a significantly greater mean reduction (8.49 ± 5.09 mm) compared to Group 1 (4.36 ± 1.46 mm) (p = 0.008). At 24 months, both groups had comparable outcomes (Group 1: 1.12 ± 0.98 mm; Group 2: 2.41 ± 5.15 mm; p = 0.356), with most lesions nearly or fully resolved. Histopathology confirmed radicular cysts in decompressed cases. Conclusions: Conservative endodontic therapy is effective for large periapical lesions. Adjunctive decompression accelerates early healing, particularly in extensive cases, potentially reducing the need for surgical intervention. CBCT is valuable for monitoring healing.

23 October 2025 in Dentistry Journal
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BDBianca Dragoș
Bianca Dragoș
DBDana Cristina Bratu
Dana Cristina Bratu
GPGeorge Popa
George Popa
MLMagda-Mihaela Luca
Magda-Mihaela Luca
RBRemus-Christian Bratu
Remus-Christian Bratu
Cosmin SinescuCosmin Sinescu
Cosmin Sinescu
Background and Objectives: Orthodontic auxiliaries create plaque-retentive niches that may amplify biofilm accumulation and inflame adjacent soft tissues. While cross-sectional comparisons suggest higher palatal burden beneath acrylic elements, less is known about real-world patterns accumulated across years of routine care. We retrospectively evaluated periodontal and palatal outcomes, and, in a microbiology sub-sample, site-specific colonization, across three device types: molar bands, Nance buttons, and removable acrylic plates. Methods: We reviewed 2022–2025 records from a university orthodontic service, including consecutive patients aged 18–30 years with documented pre-placement and 6-month follow-up indices. Groups were bands (n = 92), Nance (n = 78), acrylic (n = 76). Standardized charted measures were abstracted: Plaque Index (PI), Gingival Index (GI), bleeding on probing (BOP%), probing depth (PD), and palatal erythema grade (0–3). A laboratory sub-sample (n = 174 visits) had archived swabs cultured for total aerobic counts (log10 CFU/cm2) at the device, adjacent enamel, and palatal mucosa; Streptococcus mutans burden was available from qPCR (log10 copies/mL). Results: Baseline characteristics were similar, except for longer wear at follow-up in Nance (10.1 ± 4.0 months) vs. bands (8.7 ± 3.2) and acrylic (6.9 ± 3.0; p < 0.001). At 6 months, device type was associated with greater worsening of PI and GI (both p < 0.001) and with higher palatal erythema (bands 0.7 ± 0.5; Nance 1.6 ± 0.8; acrylic 1.9 ± 0.7; p < 0.001). Microbiologically, palatal mucosal colonization was lowest with bands (3.3 ± 0.5), higher with Nance (4.9 ± 0.6), and highest with acrylic (5.0 ± 0.7; p < 0.001); S. mutans mirrored this gradient (p < 0.001). Palatal CFU correlated with erythema (ρ = 0.6, p < 0.001) and ΔGI (ρ = 0.5, p < 0.001). In adjusted models, acrylic (OR 6.7, 95% CI 3.5–12.8) and Nance (OR 4.9, 2.5–9.3) independently predicted erythema ≥2; recent prophylaxis reduced odds (OR 0.6, 0.3–0.9). Conclusions: In this single-center cohort, palate-contacting designs were associated with higher palatal biomass and erythema than bands. These associations support device-tailored hygiene considerations and proactive palatal surveillance, particularly for acrylic components.

6 May 2022
Verified
Conference Paper
Closed access
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CNCarina-Sonia Neagu
Carina-Sonia Neagu
ACAndreea Codruta Cojocariu
Andreea Codruta Cojocariu
CZCristian Zaharia
Cristian Zaharia
Mihai RominuMihai Rominu
Mihai Rominu
Meda-Lavinia NegrutiuMeda-Lavinia Negrutiu
Meda-Lavinia Negrutiu
Cosmin SinescuCosmin Sinescu
Cosmin Sinescu
An important challenge in today’s dentistry is to create sturdy and aesthetic restorations. Dental research aims to create restorations with long-term durability and optical properties similar to healthy natural teeth. Recent works have shown that the magnetic handling of a dental adhesive doped with magnetic nanoparticles (MNPs) improves the adhesion between the composite and the dentin. This study presents the preparation of dental adhesives loaded with iron oxide (Fe3O4) NPs incorporated in SiO2 shells, and their applications in the creation of dental veneers. Extracted incisors were prepared for veneering and divided in two groups: Group A was bonded with normal adhesive and Group B was bonded with the augmented adhesive, in the presence of a permanent magnet. The samples were analyzed using stereomicroscopy, optical coherence tomography (OCT), and scanning electron microscopy (SEM), the latter combined with energy dispersive analysis of X-rays (EDAX). All techniques enabled the visualization of the veneer-adhesive and adhesive-dentin interfaces: (i) stereomicroscopy demonstrated that the adhesive layer was thinner for Group B and revealed conglomerates of MNPs in the adhesive layer; (ii) OCT enabled a visualization of the marginal closure, as well as of defects in the two interfaces; (iii) SEM provided a high-resolution image of the adhesive layer, whereas EDAX furnished an elemental analysis of the augmented adhesive. In conclusion, under the action of an external magnetic field, MNPs can penetrate deeper into the demineralized structure of the tooth, reducing the thickness of the adhesive layer and, thereby, decreasing the probability of microleakage.