Augustin Semenescu

Prof. Augustin Semenescu


Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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28 August 2020 in Sensors
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Dumitrescu CatalinDumitrescu Catalin
Dumitrescu Catalin
Marius MINEAMarius MINEA
Marius MINEA
ICIlona Mădălina COSTEA
Ilona Mădălina COSTEA
ICIonut Cosmin Chiva
Ionut Cosmin Chiva
ASAugustin Semenescu
Augustin Semenescu
The purpose of this paper is to investigate the possibility of developing and using an intelligent, flexible, and reliable acoustic system, designed to discover, locate, and transmit the position of unmanned aerial vehicles (UAVs). Such an application is very useful for monitoring sensitive areas and land territories subject to privacy. The software functional components of the proposed detection and location algorithm were developed employing acoustic signal analysis and concurrent neural networks (CoNNs). An analysis of the detection and tracking performance for remotely piloted aircraft systems (RPASs), measured with a dedicated spiral microphone array with MEMS microphones, was also performed. The detection and tracking algorithms were implemented based on spectrograms decomposition and adaptive filters. In this research, spectrograms with Cohen class decomposition, log-Mel spectrograms, harmonic-percussive source separation and raw audio waveforms of the audio sample, collected from the spiral microphone array—as an input to the Concurrent Neural Networks were used, in order to determine and classify the number of detected drones in the perimeter of interest.

26 February 2023 in Nanomaterials
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Angela SpoialăAngela Spoială
Angela Spoială
Cornelia-Ioana IlieCornelia-Ioana Ilie
Cornelia-Ioana Ilie
Ludmila MotelicaLudmila Motelica
Ludmila Motelica
Denisa FicaiDenisa Ficai
Denisa Ficai
ASAugustin Semenescu
Augustin Semenescu
Anton FICAIAnton FICAI
Anton FICAI
Cancer remains the most devastating disease, being one of the main factors of death and morbidity worldwide since ancient times. Although early diagnosis and treatment represent the correct approach in the fight against cancer, traditional therapies, such as chemotherapy, radiotherapy, targeted therapy, and immunotherapy, have some limitations (lack of specificity, cytotoxicity, and multidrug resistance). These limitations represent a continuous challenge for determining optimal therapies for the diagnosis and treatment of cancer. Cancer diagnosis and treatment have seen significant achievements with the advent of nanotechnology and a wide range of nanoparticles. Due to their special advantages, such as low toxicity, high stability, good permeability, biocompatibility, improved retention effect, and precise targeting, nanoparticles with sizes ranging from 1 nm to 100 nm have been successfully used in cancer diagnosis and treatment by solving the limitations of conventional cancer treatment, but also overcoming multidrug resistance. Additionally, choosing the best cancer diagnosis, treatment, and management is extremely important. The use of nanotechnology and magnetic nanoparticles (MNPs) represents an effective alternative in the simultaneous diagnosis and treatment of cancer using nano-theranostic particles that facilitate early-stage detection and selective destruction of cancer cells. The specific properties, such as the control of the dimensions and the specific surface through the judicious choice of synthesis methods, and the possibility of targeting the target organ by applying an internal magnetic field, make these nanoparticles effective alternatives for the diagnosis and treatment of cancer. This review discusses the use of MNPs in cancer diagnosis and treatment and provides future perspectives in the field.

1 December 2022 in Polymers
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ERElena Ruxandra Radu
Elena Ruxandra Radu
ASAugustin Semenescu
Augustin Semenescu
Stefan Ioan VoicuStefan Ioan Voicu
Stefan Ioan Voicu
Doxorubicin (DOX) is one of the most commonly used drugs in liver cancer. Unfortunately, the traditional chemotherapy with DOX presents many limitations, such as a systematic release of DOX, affecting both tumor tissue and healthy tissue, leading to the apparition of many side effects, multidrug resistance (MDR), and poor water solubility. Furthermore, drug delivery systems’ responsiveness has been intensively studied according to the influence of different internal and external stimuli on the efficiency of therapeutic drugs. In this review, we discuss both internal stimuli-responsive drug-delivery systems, such as redox, pH and temperature variation, and external stimuli-responsive drug-delivery systems, such as the application of magnetic, photo-thermal, and electrical stimuli, for the controlled release of Doxorubicin in liver cancer therapy, along with the future perspectives of these smart delivery systems in liver cancer therapy.

18 July 2024 in Polymers
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Raluca SomoghiRaluca Somoghi
Raluca Somoghi
ASAugustin Semenescu
Augustin Semenescu
VPVili Pasare
Vili Pasare
COChivu Oana
Chivu Oana
NDNițoi Dan
Nițoi Dan
BFBogdan Florea
Bogdan Florea
Epoxy resins were reinforced with different ZnO nanofillers (commercial ZnO nanoparticles (ZnO NPs), recycled ZnO and functionalized ZnO NPs) in order to obtain ZnO–epoxy composites with suitable mechanical properties, high adhesion strength, and good resistance to corrosion. The final properties of ZnO–epoxy composites depend on several factors, such as the type and contents of nanofillers, the epoxy resin type, curing agent, and preparation methods. This paper aims to review the preparation methods, mechanical and anti-corrosion performance, and applications of ZnO–epoxy composites. The epoxy–ZnO composites are demonstrated to be valuable materials for a wide range of applications, including the development of anti-corrosion and UV-protective coatings, for adhesives and the chemical industry, or for use in building materials or electronics.

28 October 2022 in Materials
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NMNurul Aida Mohd Mortar
Nurul Aida Mohd Mortar
Mohd Mustafa Al Bakri AbdullahMohd Mustafa Al Bakri Abdullah
Mohd Mustafa Al Bakri Abdullah
RRRafiza Abdul Razak
Rafiza Abdul Razak
SRShayfull Zamree Abd Rahim
Shayfull Zamree Abd Rahim
IAIkmal Hakem Aziz
Ikmal Hakem Aziz
Mohd Fathullah GhazliMohd Fathullah Ghazli
Mohd Fathullah Ghazli
Geopolymers have been intensively explored over the past several decades and considered as green materials and may be synthesised from natural sources and wastes. Global attention has been generated by the use of kaolin and calcined kaolin in the production of ceramics, green cement, and concrete for the construction industry and composite materials. The previous findings on ceramic geopolymer mix design and factors affecting their suitability as green ceramics are reviewed. It has been found that kaolin offers significant benefit for ceramic geopolymer applications, including excellent chemical resistance, good mechanical properties, and good thermal properties that allow it to sinter at a low temperature, 200 °C. The review showed that ceramic geopolymers can be made from kaolin with a low calcination temperature that have similar properties to those made from high calcined temperature. However, the choice of alkali activator and chemical composition should be carefully investigated, especially under normal curing conditions, 27 °C. A comprehensive review of the properties of kaolin ceramic geopolymers is also presented, including compressive strength, chemical composition, morphological, and phase analysis. This review also highlights recent findings on the range of sintering temperature in the ceramic geopolymer field which should be performed between 600 °C and 1200 °C. A brief understanding of kaolin geopolymers with a few types of reinforcement towards property enhancement were covered. To improve toughness, the role of zirconia was highlighted. The addition of zirconia between 10% and 40% in geopolymer materials promises better properties and the mechanism reaction is presented. Findings from the review should be used to identify potential strategies that could develop the performance of the kaolin ceramic geopolymers industry in the electronics industry, cement, and biomedical materials.

27 November 2020 in Materials
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SIMONA CAVALUSIMONA CAVALU
SIMONA CAVALU
Antoniac IulianAntoniac Iulian
Antoniac Iulian
AMAurel Mohan
Aurel Mohan
FBFlorian Bodog
Florian Bodog
CDCristian DOICIN
Cristian DOICIN
ASAugustin Semenescu
Augustin Semenescu
A novel strategy to improve the success of soft and hard tissue integration of titanium implants is the use of nanoparticles coatings made from basically any type of biocompatible substance, which can advantageously enhance the properties of the material, as compared to its similar bulk material. So, most of the physical methods approaches involve the compaction of nanoparticles versus micron-level particles to yield surfaces with nanoscale grain boundaries, simultaneously preserving the chemistry of the surface among different topographies. At the same time, nanoparticles have been known as one of the most effective antibacterial agents and can be used as effective growth inhibitors of various microorganisms as an alternative to antibiotics. In this paper, based on literature research, we present a comprehensive review of the mechanical, physical, and chemical methods for creating nano-structured titanium surfaces along with the main nanoparticles used for the surface modification of titanium implants, the fabrication methods, their main features, and the purpose of use. We also present two patented solutions which involve nanoparticles to be used in cranioplasty, i.e., a cranial endoprosthesis with a sliding system to repair the traumatic defects of the skull, and a cranial implant based on titanium mesh with osteointegrating structures and functional nanoparticles. The main outcomes of the patented solutions are: (a) a novel geometry of the implant that allow both flexible adaptation of the implant to the specific anatomy of the patient and the promotion of regeneration of the bone tissue; (b) porous structure and favorable geometry for the absorption of impregnated active substances and cells proliferation; (c) the new implant model fit 100% on the structure of the cranial defect without inducing mechanical stress; (d) allows all kinds of radiological examinations and rapid osteointegration, along with the patient recover in a shorter time.