Chronic diseases such as diabetes, heart disease, or asthma are one of the biggest health challenges of the modern world. Their management requires constant care and monitoring, which is a serious burden for healthcare systems. In the digital era, the development of telemedicine, health applications, and telemedicine platforms creates new opportunities in the treatment and monitoring of patients with chronic diseases. Telemedicine, including services such as remote consultations, telemonitoring, and remote rehabilitation, allows patients to access healthcare without having to physically visit the office. Mobile applications allow patients to monitor their health condition, receive medication reminders, or consult with doctors, which increases their involvement in the treatment process. The benefits of telemedicine include improving the availability of health services, especially in rural areas, and saving time and money. Remote monitoring of health parameters allows for a faster response in the event of a deterioration in the patient's condition, and integration with artificial intelligence technology and the Internet of Things (IoT) allows for even more accurate monitoring of health status. Health apps are particularly useful in managing chronic diseases such as diabetes or heart disease, improving control over therapy, and self-management of health. The future of telemedicine, supported by the development of technology, promises further improvements in the care of patients with chronic diseases. The introduction of more individualized medical services based on real-time data can significantly improve the quality of care and reduce the costs of treatment, constituting a key element of the future of healthcare systems.

Introduction and objective: Microplastics (MPLs) are described as synthetic polymer particles with dimensions below 5 mm. Within this group, particles measuring less than 1 µm are referred to as nanoplastics (NPLs). These particles are extensively distributed in the environment and have been...

Plastic surgery, encompassing both reconstructive and aesthetic procedures, is a field of medicine that not only enhances patients' external appearance but also significantly impacts their psychological well-being. The aim of this study is to evaluate the psychological consequences of plastic surgery, considering the effects of such interventions on self-esteem, self-worth, quality of life, and the potential risks associated with aesthetic procedures. Research indicates that procedures such as breast augmentation or rhinoplasty can lead to significant improvements in body image perception, increased self-confidence, and enhanced social and professional functioning. However, plastic surgery also carries potential risks, particularly for patients with psychological disorders such as body dysmorphic disorder or eating disorders, where the aesthetic outcomes may not meet expectations, potentially leading to a deterioration in mental health. A critical factor in preventing adverse effects is the careful selection of patients and the conduct of a thorough psychological assessment, which allows for the evaluation of realistic expectations and the identification of potential risks associated with surgery. This study emphasizes the necessity of a holistic approach to patient care, which considers both physical and psychological aspects, to ensure optimal and long-term therapeutic outcomes in plastic surgery.

Aim: This paper explores the relationship between obesity and oral diseases. Early detection and prevention of risk factors are essential for indispensable for promoting long-term health and elevating the quality of life in affected patients. Materials and methods: A search of PubMed and Google Scholar on November 10, 2024, retrieving 48 articles from 2016-2024. After screening criteria, 45 articles were included. All authors verified the final content. Conclusions: Evidence suggests a notable association between obesity and oral health issues, including periodontitis, peri-implantitis, and other gum diseases. Certain research point to the possibility that patients who undergo bariatric surgery could also experience worsening dental health. Inadequate oral hygiene and excessive sugar consumption, along with obesity, contribute to the worsening of dental problems in both children and adults. Further studies are required to better elucidate the underlying mechanisms of this association, which remains insufficiently explained in literature.

Across the world, the incidence of oral squamous cell carcinoma (OSCC) is increasing, establishing it as one of the most prevalent cancers originating in the oral cavity. Estrogen Receptor alpha (ERα) and Estrogen Receptor beta (ERβ) expression were identified and analyzed in normal oral mucosa as well as in squamous cell carcinoma. On a molecular level, estrogens and progestogens, as steroid hormones, influence various biological processes, including reproduction and behavior, by binding to their intracellular receptors. Hypotheses suggest that oral cavity malignancies could be hormonally induced. Periodontal inflammation, mediated by TREM-1, IL-1β, and reduced salivary antibacterial function during hormonal fluctuations, is important in evaluation of etiology of oral cancers and is correlated to hormonal levels. Focal adhesion kinase (FAK) signaling activates ERα through phosphorylation, increasing its transcriptional activity and promoting cell proliferation. Menopausal hormone therapy (MHT) offers both hormonal and non-hormonal treatments, with concerns about overprescription and potential off-label use. In this literature review we aimed to analyze whether there is a link between MHT which consists of estrogen or both estrogen and progesterone and oral cancer risk. A review of the scientific literature covering the years 2018–2025 was carried out, whether estrogens, identified as carcinogens, may be suggested as the potential therapeutic target for OSCC in the future, similar to their well grounded role in the standard management of estrogen receptor-positive breast cancer.

Wstęp: Pacjenci z nowotworami hematologicznymi należą do grupy szczególnego ryzyka ciężkiego przebiegu zakażenia SARS-CoV-2 ze względu na immunosupresję wynikającą z choroby podstawowej oraz stosowanego leczenia. Celem pracy była analiza przebiegu klinicznego i rokowania u dzieci z nowotworami hematologicznymi, u których wystąpiło zakażenie COVID-19. Materiał i metody: Analizie poddano troje pacjentów pediatrycznych z rozpoznanymi nowotworami hematologicznymi, hospitalizowanych w Klinice Hematologii i Onkologii Dziecięcej w Zabrzu w latach 2021–2023. Zakażenie SARS-CoV-2 potwierdzano testami antygenowymi lub metodą RT-PCR. Oceniono przebieg kliniczny, wyniki badań laboratoryjnych, zastosowane leczenie oraz dalsze losy pacjentów. Wyniki: U wszystkich pacjentów zakażenie COVID-19 powodowało konieczność czasowego przerwania leczenia przeciwnowotworowego. Dominowały objawy infekcji dróg oddechowych i zaburzenia hematologiczne (limfopenia, agranulocytoza). U dwóch chorych wystąpił zespół uwalniania cytokin wymagający podania tocilizumabu. Jeden pacjent przeżył, dwoje zmarło w wyniku progresji choroby nowotworowej po przebytym zakażeniu. Wnioski: Zakażenie SARS-CoV-2 u dzieci z nowotworami hematologicznymi może prowadzić do istotnych zaburzeń hematologicznych i przerw w terapii, mogących wpływać na rokowanie. Konieczne jest indywidualne podejście terapeutyczne oraz ścisła współpraca zespołów hematologiczno-zakaźnych w leczeniu tej grupy pacjentów.